3,883 research outputs found
On the spectroscopy of quantum dots in microcavities
At the occasion of the OECS conference in Madrid, we give a succinct account
of some recent predictions in the spectroscopy of a quantum dot in a
microcavity that remain to be observed experimentally, sometimes within the
reach of the current state of the art.Comment: OECS11 Conference proceedings, in editor style. 4 pages, 1 figure.
Animations provided separatel
Voltage-controlled Group Velocity of Edge Magnetoplasmon in the Quantum Hall Regime
We investigate the group velocity of edge magnetoplasmons (EMPs) in the
quantum Hall regime by means of time-of-flight measurement. The EMPs are
injected from an Ohmic contact by applying a voltage pulse, and detected at a
quantum point contact by applying another voltage pulse to its gate. We find
that the group velocity of the EMPs traveling along the edge channel defined by
a metallic gate electrode strongly depends on the voltage applied to the gate.
The observed variation of the velocity can be understood to reflect the degree
of screening caused by the metallic gate, which damps the in-plane electric
field and hence reduces the velocity. The degree of screening can be controlled
by changing the distance between the gate and the edge channel with the gate
voltage.Comment: 5 pages, 6 figures, to be published in Physical Review
IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.
We recently reported that the PPM1l gene encodes an endoplasmic reticulum (ER) membrane targeted protein phosphatase (named PP2Ce) with highly specific activity towards Inositol-requiring protein-1 (IRE1) and regulates the functional outcome of ER stress. In the present report, we found that the PP2Ce protein is highly expressed in lactating epithelium of the mammary gland. Loss of PP2Ce in vivo impairs physiological unfolded protein response (UPR) and induces stress kinase activation, resulting in loss of milk production and induction of epithelial apoptosis in the lactating mammary gland. This study provides the first in vivo evidence that PP2Ce is an essential regulator of normal lactation, possibly involving IRE1 signaling and ER stress regulation in mammary epithelium
PhyloCSF: a comparative genomics method to distinguish protein-coding and non-coding regions
As high-throughput transcriptome sequencing provides evidence for novel transcripts in many species, there is a renewed need for accurate methods to classify small genomic regions as protein-coding or non-coding. We present PhyloCSF, a novel comparative genomics method that analyzes a multi-species nucleotide sequence alignment to determine whether it is likely to represent a conserved protein-coding region, based on a formal statistical comparison of phylogenetic codon models. We show that PhyloCSF's classification performance in 12-species _Drosophila_ genome alignments exceeds all other methods we compared in a previous study, and we provide a software implementation for use by the community. We anticipate that this method will be widely applicable as the transcriptomes of many additional species, tissues, and subcellular compartments are sequenced, particularly in the context of ENCODE and modENCODE
Morphological Diversity between Culture Strains of a Chlorarachniophyte, Lotharella globosa
Chlorarachniophytes are marine unicellular algae that possess secondary plastids of green algal origin. Although chlorarachniophytes are a small group (the phylum of Chlorarachniophyta contains 14 species in 8 genera), they have variable and complex life cycles that include amoeboid, coccoid, and/or flagellate cells. The majority of chlorarachniophytes possess two or more cell types in their life cycles, and which cell types are found is one of the principle morphological criteria used for species descriptions. Here we describe an unidentified chlorarachniophyte that was isolated from an artificial coral reef that calls this criterion into question. The life cycle of the new strain includes all three major cell types, but DNA barcoding based on the established nucleomorph ITS sequences showed it to share 100% sequence identity with Lotharella globosa. The type strain of L. globosa was also isolated from a coral reef, but is defined as completely lacking an amoeboid stage throughout its life cycle. We conclude that L. globosa possesses morphological diversity between culture strains, and that the new strain is a variety of L. globosa, which we describe as Lotharella globosa var. fortis var. nov. to include the amoeboid stage in the formal description of L. globosa. This intraspecies variation suggest that gross morphological stages maybe lost rather rapidly, and specifically that the type strain of L. globosa has lost the ability to form the amoeboid stage, perhaps recently. This in turn suggests that even major morphological characters used for taxonomy of this group may be variable in natural populations, and therefore misleading
P-shell carriers assisted dynamic nuclear spin polarization in single quantum dots at zero external magnetic field
Repeated injection of spin polarized carriers in a quantum dot leads to the
polarization of nuclear spins, a process known as dynamic nuclear spin
polarization (DNP). Here, we report the first observation of p-shell carrier
assisted DNP in single QDs at zero external magnetic field. The nuclear field -
measured by using the Overhauser shift of the singly charged exciton state of
the QDs - continues to increase, even after the carrier population in the
s-shell saturates. This is also accompanied by an abrupt increase in nuclear
spin buildup time as p-shell emission overtakes that of the s-shell. We
attribute the observation to p-shell electrons strongly altering the nuclear
spin dynamics in the QD, supported by numerical simulation results based on a
rate equation model of coupling between electron and nuclear spin system. DNP
with p-shell carriers could open up avenues for further control to increase the
degree of nuclear spin polarization in QDs.Comment: 23 pages, 6 figure
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