GRAPE - A Balloon-Borne Gamma-Ray Polarimeter Experiment

This paper reviews the development status of GRAPE (the Gamma-Ray Polarimeter Experiment), a hard X-ray Compton Polarimeter. The purpose of GRAPE is to measure the polarization of hard X-rays in the 50-300 keV energy range. We are particularly interested in X-rays that are emitted from solar flares and gamma-ray bursts (GRBs), although GRAPE could also be employed in the study of other astrophysical sources. Accurately measuring the polarization of the emitted radiation will lead to a better understating of both emission mechanisms and source geometries. The GRAPE design consists of an array of plastic scintillators surrounding a central high-Z crystal scintillator. The azimuthal distribution of photon scatters from the plastic array into the central calorimeter provides a measure of the polarization fraction and polarization angle of the incident radiation. The design of the detector provides sensitivity over a large field-of-view (>pi steradian). The design facilitates the fabrication of large area arrays with minimal deadspace. This paper presents the latest design concept and the most recent results from laboratory tests of a GRAPE science model.Comment: 6 pages; paper presented at the FRASCATI Workshop 2005 on Multifrequency Behaviour of High Energy Cosmic Sources; submitted to Chinese Journal of Astronomy and Astrophysic

Using LaX scintillator in a new low-background Compton telescope

The ability of Compton telescopes to perform imaging and spectroscopy in space depends directly on the speed and energy resolution of the calorimeter detectors in the telescope. The calorimeter detectors flown on space-borne or balloon-borne Compton telescopes have included NaI(Tl), CsI(Na), HPGe and liquid organic scintillator. By employing LaX scintillators for the calorimeter, one can take advantage of the unique speed and resolving power of the material to improve the instrument sensitivity and simultaneously enhance its spectroscopic performance and thus its imaging performance. We present a concept for a space-borne Compton telescope that employs LaX as a calorimeter and estimate the improvement in sensitivity over past realizations of Compton telescopes. With some preliminary laboratory measurements, we estimate that in key energy bands, typically corrupted with neutron-induced internal nuclear emissions, this design enjoys a twenty-fold improvement in background rejection

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation

We have constructed a soluble chimeric fusion protein between the mouse CD8 alpha chain and the mouse CD40 T cell ligand. This protein binds to both human and mouse B cells. By itself it induced a modest degree of B cell proliferation, but together with anti-immunoglobulin (anti-Ig) antibody it greatly stimulated B cell proliferation, as determined by both [3H]thymidine uptake and increase in cell numbers. These data are evidence that the CD40 ligand on T cells provides a signal that drives B cell proliferation. This signal is synergistic with that delivered by anti-Ig antibody

Gas micro-well track imaging detectors for gamma-ray astronomy

We describe our program to develop gas micro-well detectors (MWDs) as three-dimensional charged particle trackers for use in advanced gamma-ray telescope concepts. A micro-well detector consists of an array of individual micro-patterned gas proportional counters opposite a planar drift electrode. The well anodes and cathodes may be connected in X and Y strips, respectively, to provide two-dimensional imaging. When combined with transient digitizer electronics, which record the time signature of the charge collected in the wells of each strip, full three-dimensional reconstruction of charged-particle tracks in large gas volumes is possible. Such detectors hold great promise for advanced Compton telescope (ACT) and advanced pair telescope (APT) concepts due to the very precise measurement of charged particle momenta that is possible (Compton recoil electrons and electron-positron pairs, respectively). We present preliminary lab results, including detector fabrication, prototype electronics, and initial detector testing. We also discuss applications to the ACT and APT mission concepts, based on GEANT3 and GEANT4 simulations

Position Resolution in LaBr3 and LaCl3 Scintillators Using Position-Sensitive Photomultiplier Tubes

Advanced scintillator materials such as LaBr3:Ce and LaCl3:Ce hold great promise for future hard X-ray and gamma-ray astrophysics missions due to their high density, high light output, good linearity, and fast decay times. Of particular importance for future space-based imaging instruments, such as coded-aperture telescopes, is the precise spatial location of individual gamma-ray interactions. We have investigated the position and energy resolution achievable within monolithic (5 cm × 5 cm × 1 cm) LaBr3:Ce and LaCl3:Ce crystals using position-sensitive light readout devices, including a position-sensitive photomultiplier tube and a multi-anode photomultiplier tube. We present the results of these tests and discuss the applicability of such advanced scintillators to future high-energy imaging astrophysics missions

Scintillator gamma-ray detectors with silicon photomultiplier readouts for high-energy astronomy

Space-based gamma-ray detectors for high-energy astronomy face strict constraints of mass, volume, and power, and must endure harsh operating environments. Scintillator materials have a long history of successful operation under these conditions, and new materials offer greatly improved performance in terms of efficiency, time response, and energy resolution. The use of scintillators in space remains constrained, however, by the mass, volume, and fragility of the associated light readout device, typically a vacuum photomultiplier tube (PMT). Recently developed silicon photomultipliers (SiPMs) offer gains and efficiencies similar to those of PMTs, but with greatly reduced mass and volume, high ruggedness, and no high-voltage requirements. We have therefore been investigating the use of SiPM readouts for scintillator gamma-ray detectors, with an emphasis on their suitability for space- and balloonbased instruments for high-energy astronomy. We present our most recent results, including spectroscopy measurements for lanthanum bromide scintillators with SiPM readouts, and pulse-shape discrimination using organic scintillators with SiPM readouts. We also describe potential applications of SiPM readouts to specific highenergy astronomy instrument concepts

Parental stress increases body mass index trajectory in pre-adolescents.

What is already known about this subjectRates of childhood obesity have increased since the mid-1970s. Research into behavioural determinants has focused on physical inactivity and unhealthy diets. Cross-sectional studies indicate an association between psychological stress experienced by parents and obesity in pre-adolescents.What this study addsWe provide evidence of a prospective association between parental psychological stress and increased weight gain in pre-adolescents. Family-level support for those experiencing chronic stress might help promote healthy diet and exercise behaviours in children.ObjectiveWe examined the impact of parental psychological stress on body mass index (BMI) in pre-adolescent children over 4 years of follow-up.MethodsWe included 4078 children aged 5-10 years (90% were between 5.5 and 7.5 years) at study entry (2002-2003) in the Children's Health Study, a prospective cohort study in southern California. A multi-level linear model simultaneously examined the effect of parental stress at study entry on the attained BMI at age 10 and the slope of change across annual measures of BMI during follow-up, controlled for the child's age and sex. BMI was calculated based on objective measurements of height and weight by trained technicians following a standardized procedure.ResultsA two standard deviation increase in parental stress at study entry was associated with an increase in predicted BMI attained by age 10 of 0.287 kg m(-2) (95% confidence interval 0.016-0.558; a 2% increase at this age for a participant of average attained BMI). The same increase in parental stress was also associated with an increased trajectory of weight gain over follow-up, with the slope of change in BMI increased by 0.054 kg m(-2) (95% confidence interval 0.007-0.100; a 7% increase in the slope of change for a participant of average BMI trajectory).ConclusionsWe prospectively demonstrated a small effect of parental stress on BMI at age 10 and weight gain earlier in life than reported previously. Interventions to address the burden of childhood obesity should address the role of parental stress in children

Prospects for GRB Polarimetry with GRAPE

This paper discusses the latest progress in the development of GRAPE (Gamma‐Ray Polarimeter Experiment), a hard X‐ray Compton Polarimeter. The purpose of GRAPE is to measure the polarization of hard X‐rays in the 50–300 keV energy range. We are particularly interested in X‐rays that are emitted from solar flares and gamma‐ray bursts (GRBs). Accurately measuring the polarization of the emitted radiation from these sources will lead to a better understating of both the emission mechanisms and source geometries. The GRAPE design consists of an array of plastic scintillators surrounding a central high‐Z crystal scintillator. We can monitor individual Compton scatters that occur in the plastics and determine whether the photon is photo absorbed by the high‐Z crystal or not. A Compton scattered photon that is immediately photo absorbed by the high‐Z crystal constitutes a valid event. These valid events provide us with the interaction locations of each incident photon and ultimately produces a modulation pattern for the Compton scattering of the polarized radiation. Comparing with Monte Carlo simulations of a 100% polarized beam, the level of polarization of the measured beam can then be determined. The complete array is mounted on a flat‐panel multi‐anode photomultiplier tube (MAPMT) that can measure the deposited energies resulting from the photon interactions. The design of the detector allows for a large field‐of‐view (\u3e π steradian), at the same time offering the ability to be close‐packed with multiple modules in order to reduce deadspace. We present in this paper the latest laboratory results obtained from GRAPE using partially polarized radiation sources along with a brief description of our future plans for the GRAPE design

Simulations of a monolithic lanthanum bromide gamma-ray detector

We have been working on the development of a detector design for a large area coded aperture imaging system operating in the 10-600 keV energy range. The detector design is based on an array of Lanthanum Bromide (LaBr3) scintillators, each directly coupled to a Hamamatsu 64-channel multi-anode photomultiplier tube (MAPMT). This paper focuses on the development of the GEANT4-based simulations as an aid in the optimization of the detector design. The simulations have been validated by comparisons with various laboratory data sets. We will summarize the current status and latest findings from this study