228 research outputs found
High resolution measurements of the switching current in a Josephson tunnel junction: Thermal activation and macroscopic quantum tunneling
We have developed a scheme for a high resolution measurement of the switching
current distribution of a current biased Josephson tunnel junction using a
timing technique. The measurement setup is implemented such that the digital
control and read-out electronics are optically decoupled from the analog bias
electronics attached to the sample. We have successfully used this technique to
measure the thermal activation and the macroscopic quantum tunneling of the
phase in a small Josephson tunnel junction with a high experimental resolution.
This technique may be employed to characterize current-biased Josephson tunnel
junctions for applications in quantum information processing.Comment: 10 pages, 8 figures, 1 tabl
Dilation of the Giant Vortex State in a Mesoscopic Superconducting Loop
We have experimentally investigated the magnetisation of a mesoscopic
aluminum loop at temperatures well below the superconducting transition
temperature . The flux quantisation of the superconducting loop was
investigated with a -Hall magnetometer in magnetic field intensities
between . The magnetic field intensity periodicity observed in
the magnetization measurements is expected to take integer values of the
superconducting flux quanta . A closer inspection of the
periodicity, however, reveal a sub flux quantum shift. This fine structure we
interpret as a consequence of a so called giant vortex state nucleating towards
either the inner or the outer side of the loop. These findings are in agreement
with recent theoretical reports.Comment: 12 pages, 5 figures. Accepted for publication in Phys. Rev.
In the light of directed evolution: Pathways of adaptive protein evolution
Directed evolution is a widely-used engineering strategy for improving the stabilities or biochemical functions of proteins by repeated rounds of mutation and selection. These experiments offer empirical lessons about how proteins evolve in the face of clearly-defined laboratory selection pressures. Directed evolution has revealed that single amino acid mutations can enhance properties such as catalytic activity or stability and that adaptation can often occur through pathways consisting of sequential beneficial mutations. When there are no single mutations that improve a particular protein property experiments always find a wealth of mutations that are neutral with respect to the laboratory-defined measure of fitness. These neutral mutations can open new adaptive pathways by at least 2 different mechanisms. Functionally-neutral mutations can enhance a protein's stability, thereby increasing its tolerance for subsequent functionally beneficial but destabilizing mutations. They can also lead to changes in “promiscuous” functions that are not currently under selective pressure, but can subsequently become the starting points for the adaptive evolution of new functions. These lessons about the coupling between adaptive and neutral protein evolution in the laboratory offer insight into the evolution of proteins in nature
An Evening Sector Ps 6 - Omega Band Event
Article draft. Author list indicative and roughly corresponds to amount of contribution to the article to date.Abstract. Ps 6 magnetic disturbances and associated optical
forms known as omega bands are usually associated
with the morning sector. Some evidence for similar phenomenology
in the evening sector has been presented by
Solovyev et al. (1999). We confirm and extend those results
with high time resolution magnetic and imaging observations
from Athabasca University Geophysical Observatory
for an event that took place on July 27, 2003, along with conjugate
hemisphere imaging from the Polar spacecraft. The
observed signatures indicate sunward drift (westward in the
evening sector). Magnetic perturbations feature negative Y
and transitional Z indicating westward passage of poleward
equivalent currents overhead. As has been suggested by Connors
et al. (2003) to be often the case for morning sector Ps
6/omega bands, initiation of the evening sector event coincided
with substorm onset. From optical and magnetic data
we obtain consistent results for the drift rate of the forms,
which changed during the event. An inner magnetospheric
source is suggested, with triggering of the onset by an increase
in solar wind speed
Thermal effects on atomic friction
We model friction acting on the tip of an atomic force microscope as it is
dragged across a surface at non-zero temperatures. We find that stick-slip
motion occurs and that the average frictional force follows ,
where is the tip velocity. This compares well to recent experimental work
(Gnecco et al, PRL 84, 1172), permitting the quantitative extraction of all
microscopic parameters. We calculate the scaled form of the average frictional
force's dependence on both temperature and tip speed as well as the form of the
friction-force distribution function.Comment: Accepted for publication, Physical Review Letter
Metastability in Josephson transmission lines
Thermal activation and macroscopic quantum tunneling in current-biased
discrete Josephson transmission lines are studied theoretically. The degrees of
freedom under consideration are the phases across the junctions which are
coupled to each other via the inductances of the system. The resistively
shunted junctions that we investigate constitute a system of N interacting
degrees of freedom with an overdamped dynamics. We calculate the decay rate
within exponential accuracy as a function of temperature and current. Slightly
below the critical current, the decay from the metastable state occurs via a
unique ("rigid") saddlepoint solution of the Euclidean action describing the
simultaneous decay of the phases in all the junctions. When the current is
reduced, a crossover to a regime takes place, where the decay occurs via an
"elastic" saddlepoint solution and the phases across the junctions leave the
metastable state one after another. This leads to an increased decay rate
compared with the rigid case both in the thermal and the quantum regime. The
rigid-to-elastic crossover can be sharp or smooth analogous to first- or
second- order phase transitions, respectively. The various regimes are
summarized in a current-temperature decay diagram.Comment: 11 pages, RevTeX, 3 PS-figures, revised versio
Near-field optical power transmission of dipole nano-antennas
Nano-antennas in functional plasmonic applications require high near-field optical power transmission. In this study, a model is developed to compute the near-field optical power transmission in the vicinity of a nano-antenna.
To increase the near-field optical power transmission from a nano-antenna, a tightly focused beam of light is utilized to illuminate a metallic nano-antenna. The modeling and simulation of these structures is performed using 3-D finite element method based full-wave solutions of Maxwell’s equations. Using the optical power transmission model, the interaction of a focused beam of light with plasmonic nanoantennas is investigated. In addition, the tightly focused beam of light is passed through a band-pass filter to identify the effect of various regions of the angular spectrum to the near-field radiation of a dipole nano-antenna. An extensive parametric study is performed to quantify the effects of various parameters on the transmission efficiency of dipole nano-antennas, including length, thickness, width, and the composition of the antenna, as well as the wavelength and half-beam angle of incident light. An optimal dipole nanoantenna geometry is identified based on the parameter studies in this work. In addition, the results of this study show the interaction of the optimized dipole nano-antenna with a magnetic recording medium when it is illuminated with a focused beam of light
Crossover from thermal hopping to quantum tunneling in Mn_{12}Ac
The crossover from thermal hopping to quantum tunneling is studied. We show
that the decay rate with dissipation can accurately be determined near
the crossover temperature. Besides considering the Wentzel-Kramers-Brillouin
(WKB) exponent, we also calculate contribution of the fluctuation modes around
the saddle point and give an extended account of a previous study of crossover
region. We deal with two dangerous fluctuation modes whose contribution can't
be calculated by the steepest descent method and show that higher order
couplings between the two dangerous modes need to be taken into considerations.
At last the crossover from thermal hopping to quantum tunneling in the
molecular magnet Mn_{12}Ac is studied.Comment: 10 pages, 3 figure
Sonoluminescence as a QED vacuum effect. I: The Physical Scenario
Several years ago Schwinger proposed a physical mechanism for
sonoluminescence in terms of changes in the properties of the
quantum-electrodynamic (QED) vacuum state. This mechanism is most often phrased
in terms of changes in the Casimir Energy: changes in the distribution of
zero-point energies and has recently been the subject of considerable
controversy. The present paper further develops this quantum-vacuum approach to
sonoluminescence: We calculate Bogolubov coefficients relating the QED vacuum
states in the presence of a homogeneous medium of changing dielectric constant.
In this way we derive an estimate for the spectrum, number of photons, and
total energy emitted. We emphasize the importance of rapid spatio-temporal
changes in refractive indices, and the delicate sensitivity of the emitted
radiation to the precise dependence of the refractive index as a function of
wavenumber, pressure, temperature, and noble gas admixture. Although the
physics of the dynamical Casimir effect is a universal phenomenon of QED,
specific experimental features are encoded in the condensed matter physics
controlling the details of the refractive index. This calculation places rather
tight constraints on the possibility of using the dynamical Casimir effect as
an explanation for sonoluminescence, and we are hopeful that this scenario will
soon be amenable to direct experimental probes. In a companion paper we discuss
the technical complications due to finite-size effects, but for reasons of
clarity in this paper we confine attention to bulk effects.Comment: 25 pages, LaTeX 209, ReV-TeX 3.2, eight figures. Minor revisions:
Typos fixed, references updated, minor changes in numerical estimates, minor
changes in some figure
Bidirectional lipid droplet velocities are controlled by differential binding strengths of HCV Core DII protein
Host cell lipid droplets (LD) are essential in the hepatitis C virus (HCV) life cycle and are targeted by the viral capsid core protein. Core-coated LDs accumulate in the perinuclear region and facilitate viral particle assembly, but it is unclear how mobility of these LDs is directed by core. Herein we used two-photon fluorescence, differential interference contrast imaging, and coherent anti-Stokes Raman scattering microscopies, to reveal novel core-mediated changes to LD dynamics. Expression of core protein’s lipid binding domain II (DII-core) induced slower LD speeds, but did not affect directionality of movement on microtubules. Modulating the LD binding strength of DII-core further impacted LD mobility, revealing the temporal effects of LD-bound DII-core. These results for DII-core coated LDs support a model for core-mediated LD localization that involves core slowing down the rate of movement of LDs until localization at the perinuclear region is accomplished where LD movement ceases. The guided localization of LDs by HCV core protein not only is essential to the viral life cycle but also poses an interesting target for the development of antiviral strategies against HCV
- …