49 research outputs found
Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1
The European Integrated Tokamak Modelling Effort:Achievements and First Physics Results
This article compares both new and commonly used boundary conditions for generating pressure-driven water flows through carbon nanotubes in molecular dynamics simulations. Three systems are considered: (1) a finite carbon nanotube membrane with streamwise periodicity and ‘gravity’-type Gaussian forcing, (2) a non-periodic finite carbon nanotube membrane with reservoir pressure control, and (3) an infinite carbon nanotube with periodicity and ‘gravity’-type uniform forcing. Comparison between these focuses on the flow behaviour, in particular the mass flow rate and pressure gradient along the carbon nanotube, as well as the radial distribution of water density inside the carbon nanotube. Similar flow behaviour is observed in both membrane systems, with the level of user input required for such simulations found to be largely dependent on the state controllers selected for use in the reservoirs. While System 1 is simple to implement in common molecular dynamics codes, System 2 is more complicated, and the selection of control parameters is less straightforward. A large pressure difference is required between the water reservoirs in these systems to compensate for large pressure losses sustained at the entrance and exit of the nanotube. Despite a simple set-up and a dramatic increase in computational efficiency, the infinite length carbon nanotube in System 3 does not account for these significant inlet and outlet effects, meaning that a much smaller pressure gradient is required to achieve a specified mass flow rate. The infinite tube set-up also restricts natural flow development along the carbon nanotube due to the explicit control of the fluid. Observation of radial density profiles suggests that this results in over-constraint of the water molecules in the tube
Un instrument de court terme pour stimuler la concurrence le gas release
This paper develops a simple model for examining the gas-release programs as the unique tool to improve the performance of imperfectly competitive natural gas markets. We study the «artificial» duopoly effect created by first the incumbent and then by a regulator who introduces a gas-release program under both a partial and a global budget-balance constraint imposed on the incumbent. Calibration and simulation techniques are used to compare these scenarios under different assumptions on the way regulation is conducted. © Presses de Sciences Po
Gateway: New high performance computing facility for EFDA task force on integrated Tokamak modelling
The EFDA task force on Integrated Tokamak Modelling (ITM-TF) is providing the EU fusion community with a complete and flexible suite of reliable software tools and codes able to simulate the next ITER and DEMO plasma discharges. EFDA has launched the Gateway project as the first computing facility to be jointly used by EU fusion associations.
The Gateway has been designed to allow the ITM-TF members to work together on a common platform and share their codes, developments tools and technologies as well as to make able the inter-operation with tera-scale supercomputer facilities. Technically the Gateway is a rather small high computing facility in operation since 2008, with 1 Teraflops of theoretical peak and 100 Terabytes shared storage area for experimental and simulation data.
This paper describes the information technologies involved in the Gateway facility, particularly as regards the low latency interconnect network for multi-core platform as well as fast I/O solutions implemented with storage over Infiniband and high performance parallel file systems. The solutions adopted on the Gateway facility had undergone to specific benchmarks showing excellent performances in typical fusion data handling issues. Finally the interoperability between Gateway and ENEA CRESCO supercomputer will be described showing the access solutions that allow the exploitation of tera-scale supercomputer facilities
Un instrument de court terme pour stimuler la concurrence le gas release
This paper develops a simple model for examining the gas-release programs as the unique tool to improve the performance of imperfectly competitive natural gas markets. We study the «artificial» duopoly effect created by first the incumbent and then by a regulator who introduces a gas-release program under both a partial and a global budget-balance constraint imposed on the incumbent. Calibration and simulation techniques are used to compare these scenarios under different assumptions on the way regulation is conducted. © Presses de Sciences Po