3,657 research outputs found

    Growing up with Robots

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    Piaget’stheoryofcognitivedevelopment[1] isconsideredafundamentalpedagogicaltoolthat indifferentapproaches,educatorsatdifferent levelsandsituationwidelyuse.Thevastmajorityofstudentshavetendency tolearninaconcretemannerbyexperiencingor feeling,andprocesstheinformationactivelyby experimentingdoingoractingupon[2].Hands-onexperimentalactivitieshavelong timeprovedtobeoneofthemosteffectiveways todrivethestudentstoasuccessfullearningof scienceandtechnology[3].Constructivismisapedagogicalapproach whereinastructuredwaythelearningprocessis centredintheprocessofbuildingorconstructing something

    Influence of Lu content on (LuxGd1-x)2SiO5 oxyorthosilicates grown by Laser Floating Zone: structural studies and transparency

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    Lutetium gadolinium oxyorthosilicates (LGSO, (LuxGd1-x)2SiO5, x = 0.1, 0.3 and 0.5)) were obtained by the Laser Floating Zone (LFZ) in air at 10 mm/h, much faster than those produced by the standard Czochralski method. The LGSO fibres were structural and optically characterized. Scanning electron microscopy (SEM/EDS) allowed observing homogeneous monophasic crystalline fibres that obey the expected phase transition from P21/c to C2/c monoclinic structures, as revealed by X-Ray diffraction and Raman spectroscopy. Finally, transmission studies in the near UV to visible range allowed to quantify the transmission and to appraise the presence of energy transfer bands that favor their use as host materials in photonic applications.publishe

    Downstream processing of co-amorphous olanzapine

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    Abstract of poster presented at the 12th PBP World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Wien, Austria, 11-14 May 2021 (virtual meeting)N/

    Prescribed Fire Plus Grazing Horses: A Sustainable Model to Decrease Fire Hazard in a Mountain Landscape

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    The mountain landscapes of northern Portugal have been modified through rural depopulation and the absence of rangeland management. As such, increased above-ground biomass and higher fire hazard resulted, as well as decreased ecosystem biodiversity. The objectives of the OpentoPreserve Interreg SUDOE project are to evaluate the effects of the combined use of prescribed fire with grazing horses, and also to develop strategies of socio-economic valorization of this model. Concerning the evaluation of prescribed fire and grazing effects, the experimental design consisted of three plots in the Natura 2000 Alvão/Marão Site, respectively Control, Fire x Grazing, and Fire. The Fire plots were burned in early spring and vegetation percent cover and height were measured in all plots in late spring. We have implemented four transects in the three different plots, used the line intercept method and subsequently estimated vegetation volume. This methodology is also applied on Forestation of Agricultural Land with More Silviculture, Silvopasture, Innovation and Value project. Concerning socio-economic valorization, the stakeholders related to the native horse breed, were interviewed and a focus-group was held. The study intends to identify both the benefits resulting from the adoption of a management system that includes the native horse breed, named Garrano, and the main weaknesses related to environmental, economic and social sustainability. Initial results for total vegetation in each plot show a high reduction in vegetation percent cover and its volume in the burned plots (33.5% and 268.3 m3 ha-1) in comparison to the control plot (183.7% and 12862.5 m3 ha-1). Furthermore, a fast recovery was observed in July, mainly of the Pterospartum tridentatum shrub species. Interviews and focus-group results shows the important role of these grazing animals in vegetation control as well as in other ecosystems services, involving an environmental and a socio-economic dimension. A strategy to value contribution to the economy of agricultural holdings has been proposed

    Addressing drug solubility problems : a case-study

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    Poster presented at the 10th iMed.ULisboa Postgraduate Students Meeting & 3rd i3DU Meeting. 24-25 Julho 2018, LisboaN/

    Development of an at-line method to monitor the conversion of amorphous into crystalline Olanzapine, in dry blends of wet masses

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    Abstract of the poster presented at the 3rd European Conference on Pharmaceutics. 25-26 march 2019, Bologne, ItalyN/

    Co-amorphization of olanzapine and saccharin : a pathway to increase solubility in water

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    Communication presented at the 12th Annual Symposium, Pharmaceutical Solid State Research Cluster (PSSRC). 12-14 September 2018, Leuven, BelgiumN/

    Cohesiveness of powdered co-amorphous Olanzapine and impact on tablet production

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    Communication abstract: Proceedings of the 5th International Congress of CiiEM - Reducing inequalities in Health and Society, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from June 16th to 18th, 2021.This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The evaluation of the processability of co-amorphous mixtures is of paramount importance since these systems are increasingly used to address the poor solubility presented by most of the drugs in research and development. This work shows that co-amorphous olanzapine powders present higher cohesiveness than their crystalline counterpart and resulted in the production of tablets with a higher tensile strength and a slower release of the drug. As a result, this work demonstrates that despite the solubility advantages of co-amorphous mixtures, consideration should be given to the downstream processing of formulations containing such materials.info:eu-repo/semantics/publishedVersio

    Assessment of the stability of co-amorphous Olanzapine in tablets

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    Abstract of the poster presented at the 4th International Congress of CiiEM - "Health, Well-being and Ageing in the XXI Century." 2-5 June 2019, Monte de Caparica, PortugalN/

    Drug-excipient and drug-drug mixtures : a pathway for the production of co-amorphous entities

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    Abstract of the communication presented at the 3rd International Congress of CiiEM ‘Research and Innovation in Human and Health Sciences’. Campus Egas Moniz, Caparica, Portugal, June 20-22, 2018N/
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