The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle.

In the mammalian ovary, great interest in the expression and function of the bone morphogenetic protein (BMP) family has been recently generated from evidence of their critical role in determining folliculogenesis and female fertility. Despite extensive work, there is a need to understand the cellular sites of expression of these important regulatory molecules, and how their gene expression changes within the basic ovary cell types through the cycle. Here we have performed a detailed in situ hybridization analysis of the spatial and temporal expression patterns of the BMP ligands (BMP-2, -3, -3b, -4, -6, -7, -15), receptors (BMPR-IA, -IB, -II), and BMP antagonist, follistatin, in rat ovaries over the normal estrous cycle. We have found that: i) all of the mRNAs are expressed in a cell-specific manner in the major classes of ovary cell types (oocyte, granulosa, theca interstitial, theca externa, corpora lutea, secondary interstitial, vascular and ovary surface epithelium); and ii) most undergo dynamic changes during follicular and corpora luteal morphogenesis and histogenesis. The general principle to emerge from these studies is that the developmental programs of folliculogenesis (recruitment, selection, atresia), ovulation, and luteogenesis (luteinization, luteolysis) are accompanied by rather dramatic spatial and temporal changes in the expression patterns of these BMP genes. These results lead us to hypothesize previously unanticipated roles for the BMP family in determining fundamental developmental events that ensure the proper timing and developmental events required for the generation of the estrous cycle

Analytical calculation of the areas of Saturn's disk and rings

The area of the visible disk, the area of the ansae (visible rings not overlapping the disk), and the area of overlap (visible rings overlapping the disk) were analytically determined to account for the thermal emission from the rings. These parameters were available in the ephemeris

WINDOW: A computer program for planning astronomical observations

A FORTRAN computer program called WINDOW was written to simplify the planning of astronomical observations of a number of objects in a limited time. The program lists the azimuths at 15 minute intervals of up to 20 objects while they are in a given range of elevation angles - the window - and gives the elevation angle of each object at its time of transit. This work was motivated by the need to use observing time efficiently on flights of NASA-Ames' Lear Jet and C-141 observatories; WINDOW permits the investigator to prepare preliminary flight plans. However, the program is suited to planning ground-based observations as well. The program and a sample flight plan are described

SOFIA: Stratospheric Observatory for Infrared Astronomy

SOFIA will be a three meter class telescope operating in a Boeing 747, offering astronomers routine access to infrared wavelengths unavailable from the ground, and with the means to observe transient astronomical events from anywhere in the world. The concept is based on 15 years of experience with NASA's Kuiper Airborne Observatory (KAO), which SOFIA will replace in the mid 1990's. SOFIA's wavelength range covers nearly four decades of the electromagnetic spectrum: from the visible, throughout the infrared and submillimeter, to the microwave region. Relative to the KAO, SOFIA will be roughly ten times more sensitive for compact sources, enabling observations of fainter objects and measurements at higher spectral resolution. Also, it will have three times the angular resolving power for wavelengths greater than 30 microns, permitting more detailed imaging at far infrared wavelengths

Engineering tests of the C-141 telescope

Data on image quality, chopper performance, and the closed-loop operation of the 91 cm telescope of the Kuiper Airborne Observatory which were obtained in September 1977 are presented

Improvement of maneuver aerodynamics by spanwise blowing

Spanwise blowing was used to test a generalized wind-tunnel model to investigate component concepts in order to provide improved maneuver characteristics for advanced fighter aircraft. Primary emphasis was placed on performance, stability, and control at high angles of attack and subsonic speeds. Test data were obtained in the Langley high speed 7 by 10 foot tunnel at free stream Mach numbers up to 0.50 for a range of model angles of attack, jet momentum coefficients, and leading and trailing edge flap deflection angles. Spanwise blowing on a 44 deg swept trapezoidal wing resulted in leading edge vortex enhancement with subsequent large vortex induced lift increments and drag polar improvements at the higher angles of attack. Small deflections of a leading edge flap delayed these lift and drag benefits to higher angles of attack. In addition, blowing was more effective at higher Mach numbers. Spanwise blowing in conjunction with a deflected trailing edge flap resulted in lift and drag benefits that exceeded the summation of the effects of each high lift device acting alone. Asymmetric blowing was an effective lateral control device at the higher angles of attack

Recent advancements in information extraction methodology and hardware for Earth Resources Survey Systems

There are no author-identified significant results in this report

An investigation of the optimization of parameters affecting the implementation of fourier transform spectroscopy at 20-500 micron from the C-141 airborne infrared observatory

A program for 20-500 micron spectroscopy from the NASA flying C141 infrared observatory is being carried out with a Michelson interferometer. The parameters affecting the performance of the instrument are studied and an optimal configuration for high performance on the C-141 aircraft is recommended. As each parameter is discussed the relative merits of the two modes of mirror motion (rapid scan or step and integrate) are presented

Investigation related to multispectral imaging systems

A summary of technical progress made during a five year research program directed toward the development of operational information systems based on multispectral sensing and the use of these systems in earth-resource survey applications is presented. Efforts were undertaken during this program to: (1) improve the basic understanding of the many facets of multispectral remote sensing, (2) develop methods for improving the accuracy of information generated by remote sensing systems, (3) improve the efficiency of data processing and information extraction techniques to enhance the cost-effectiveness of remote sensing systems, (4) investigate additional problems having potential remote sensing solutions, and (5) apply the existing and developing technology for specific users and document and transfer that technology to the remote sensing community

Effects of spanwise blowing on the surface pressure distribution and vortex-lift characteristics of a trapezoidal wing-strake configuration

The effects of spanwise blowing on the surface pressures of a 44 deg swept trapezoidal wing-strake configuration were measured. Wind tunnel data were obtained at a free stream Mach number of 0.26 for a range of model angle of attack, jet thrust coefficient, and nozzle chordwise location. Results showed that spanwise blowing delayed the leading edge vortex breakdown to larger span distances and increased the lifting pressures. Vortex lift was achieved at span stations immediately outboard of the strake-wing junction with no blowing, but spanwise blowing was necessary to achieve vortex lift at increased span distances. Blowing on the wing in the presence of the strake was not as effective as blowing on the wing alone. Spanwise blowing increased lift throughout the angle-of-attack range, improved the drag polars, and extended the linear pitching moment to higher values of lift. The leading edge suction analogy can be used to estimate the effects of spanwise blowing on the aerodynamic characteristics