water pvt collectors performance comparison

Abstract Flat plate PVT water based technology presents many advantages in terms of overall performance and space saving than the PV modules and the solar thermal collectors installed separately. However, the electrical and the thermal performances of the PVT technologies are more deeply related to different influences factors, among which: the presence or absence of the air gap formed by the transparent frontal cover, the absorber configuration and the adopted PV technology. For that reasons, the proposed research is aimed to assess, under the energy point of view, a comparison between a covered and an uncovered PVT water collectors, realized with different PV cells coupled to two aluminium roll-bond absorbers characterized also by different channel arrangements. The performance analysis is based on energy simulations carried out with two mathematical models validated on experimental data at the Test Facility of the Politecnico di Milano

Long-term reliability of photovoltaic c-Si modules - A detailed assessment based on the first Italian BIPV project

Assessing the long-term reliability of PV systems is important for understanding their energy and cost efficiency. Typically, estimates and predictions are based on indoor tests and accelerated ageing. However, fluctuating and differently interacting outdoor factors such as solar radiation, dust, and shadowing in real environment can impact the actual performance. This paper examines alterations related to ageing of c-Si PV modules, firstly by classifying the main factors that affect aged c-Si PV modules and then assessing the impact on their performance degradation by analysing a pilot BIPV system at Politecnico di Milano after 20 years of actual operation. Such system, which is highly representative since is the first public BIPV plant funded in Italy, was carefully and continuously monitored during its operating life. In particular, according to the visual/IR inspection carried out after the 20th year of operation, the main observed alteration in the modules were discoloration of the encapsulant, delamination, and chalking of the backsheet. The I-V characterization shown that all sampled modules had an overall degradation rate of less than 20 %, which is within the warranty limit, although in many cases the degradation rate over time shows a non-linear trend. Only one module experienced a severe fault that caused the complete loss of functionality. Obtained results confirm the reliability of c-Si technology, stressing the importance of a careful monitoring especially after the 15th year, when an increase of the degradation rate might occur

Towards Sustainability Assessment of the Built Environment: A Classification of the Existing Challenges

The application of sustainability assessment in a decision context is associated with various challenges that explain why the transition to action-oriented knowledge still needs to be fulfilled. Therefore, this paper aims to explore the associated challenges in sustainability assessment in the decision context of the built environment. Several publications are reviewed to provide a systemic understanding of the associated complexities. The challenges in sustainability assessment in the built environment are categorized at different levels, from understanding to measurement and implementation. The challenges are further categorized into definition, context, interpretation, data, measurement methods, uncertainties, indicators and indices, results, coordination, conflicts, and action-oriented knowledge. Moreover, according to the nature of each challenge, they are classified into epistemological, methodological, and procedural challenges. The novelty of this review is that it reviews and reports almost all fragmentedly reported challenges in sustainability assessment of the built environment in the literature within a holistic framework that provides a clear understanding of the state of the art and second discusses them within an integrated framework (the Sustainability Assessment Network) including the position of active-role players to resolve them, including strategists, scientist, and stakeholders

POZ-, AT-hook-, and Zinc Finger-containing Protein (PATZ) Interacts with Human Oncogene B Cell Lymphoma 6 (BCL6) and Is Required for Its Negative Autoregulation.

The PATZ1 gene encoding a POZ/AT-hook/Kruppel zinc finger (PATZ) transcription factor, is considered a cancer-related gene because of its loss or misexpression in human neoplasias. As for other POZ/domain and Kruppel zinc finger (POK) family members, the transcriptional activity of PATZ is due to the POZ-mediated oligomer formation, suggesting that it might be not a typical transactivator but an architectural transcription factor, thus functioning either as activator or as repressor depending on the presence of proteins able to interact with it. Therefore, to better elucidate PATZ function, we searched for its molecular partners. By yeast two-hybrid screenings, we found a specific interaction between PATZ and BCL6, a human oncogene that plays a key role in germinal center (GC) derived neoplasias. We demonstrate that PATZ and BCL6 interact in germinal center-derived B lymphoma cells, through the POZ domain of PATZ. Moreover, we show that PATZ is able to bind the BCL6 regulatory region, where BCL6 itself acts as a negative regulator, and to contribute to negatively modulate its activity. Consistently, disruption of one or both Patz1 alleles in mice causes focal expansion of thymus B cells, in which BCL6 is up-regulated. This phenotype was almost completely rescued by crossing Patz1(+/-) with Bcl6(+/-) mice, indicating a key role for Bcl6 expression in its development. Finally, a significant number of Patz1 knock-out mice (both heterozygous and homozygous) also develop BCL6-expressing lymphomas. Therefore, the disruption of one or both Patz1 alleles may favor lymphomagenesis by activating the BCL6 pathway

The PALM Technique: histological findings of masked phototherapeutic keratectomy on rabbit corneas

BACKGROUND: To compare the corneal healing response between conventional and phototherapeutic keratectomy through a masking agent, in rabbit corneas. METHODS: 24 adult rabbits underwent phototherapeutic keratectomy. Animals were divided in two groups: 12 received photoablation through a masking agent (PALM gel) and the remaining 12 received conventional phototherapeutic keratectomy of equal depth and served as control. Light and transmission electron microscopy was performed in specimens of both groups obtained: immediately after, four hours, one week, one, three and six months after treatment. RESULTS: Reepitheliazation was complete within five days in all eyes. Light and transmission electron microscopy did not reveal any differences of the healing process in the experimental eyes compared to the controls. CONCLUSION: Photoablation through the PALM technique did not result any evident alterations of the reepithelisation and stromal healing process

Evolution of the avian β-defensin and cathelicidin genes

Background: β-defensins and cathelicidins are two families of cationic antimicrobial peptides (AMPs) with a broad range of antimicrobial activities that are key components of the innate immune system. Due to their important roles in host defense against rapidly evolving pathogens, the two gene families provide an ideal system for studying adaptive gene evolution. In this study we performed phylogenetic and selection analyses on β-defensins and cathelicidins from 53 avian species representing 32 orders to examine the evolutionary dynamics of these peptides in birds. Results and conclusions: Avian β-defensins are found in a gene cluster consisting of 13 subfamiles. Nine of these are conserved as one to one orthologs in all birds, while the others (AvBD1, AvBD3, AvBD7 and AvBD14) are more subject to gene duplication or pseudogenisation events in specific avian lineages. Avian cathelicidins are found in a gene cluster consisting of three subfamilies with species-specific duplications and gene loss. Evidence suggested that the propiece and mature peptide domains of avian cathelicidins are possibly co-evolving in such a way that the cationicity of the mature peptide is partially neutralised by the negative charge of the propiece prior to peptide secretion (further evidence obtained by repeating the analyses on primate cathelicidins). Negative selection (overall mean d