2 research outputs found
Jelenkori és múltbeli hidrogeológiai folyamatok sztochasztikus modelljei, ezek értékelése és földtani értelmezése = Stochastic models of recent and paleo- hydrogeological processes, their evaluation and geological interpretation
A felszĂn alatti vizek hidrográfjait alakĂtĂł látens hatások hatások azonosĂtására, Ă©s ezek intenzitásának számszerűsĂtĂ©sĂ©re szolgálĂł dinamikus faktoranalĂzis (DFA) alkalmazási körĂ©t szĂ©lesĂtettĂĽk. TettĂĽk ezt karsztos viszonyok között terĂĽleti kiterjesztĂ©ssel, valamint nem-karsztos ĂĽledĂ©kes környezet talajvĂzszint adatainak elemzĂ©sĂ©vel. A DFA a vĂztartĂł sĂ©rĂĽlĂ©kenysĂ©gĂ©nek hatĂ©kony mĂ©rĹ‘számát nyĂşjtja a látens hatások intenzitását reprezentálĂł faktorsĂşlyok segĂtsĂ©gĂ©vel. A Szigetközben a faktorsĂşlyok változása jĂłl kimutatja a Duna betáplálási helyĂ©nek az elterelĂ©s következtĂ©ben kialakulĂł mintegy 15 km-es elmozdulását. KĂ©t fontos modellt alkottunk folyĂłk napi vĂzhozam idĹ‘sorának leĂrására, elemeztĂĽk becslĂ©seik tulajdonságát, Ă©s illesztettĂĽk a Tisza Ă©s a Duna adataira. Az elsĹ‘ modellben egy általánosĂtott bĂ©ta-ARCH zajt bocsátunk át egy ARMA szűrĹ‘n, mĂg a másikban egy szemi-Markov rezsimindikátor folyamat vezĂ©rli gamma bolyongások Ă©s Gauss AR(1) folyamatok váltakozásait a fel- Ă©s leszállĂł rezsimeknek megfelelĹ‘en. A modellek extrĂ©m Ă©rtĂ©k tulajdonságait vizsgáltuk elmĂ©letileg Ă©s szimuláciĂłval, majd összvetettĂĽk a valĂłs adatokkal, jĂł egyezĂ©st nyerve. EredmĂ©nyeinket felhasználtuk biztosĂtĂłk árvĂzkockázatának elemzĂ©sĂ©ben. Az aggteleki karszton repedĂ©srendszerek kiĂĽrĂĽlĂ©si idejĂ©t határoztuk meg 5 forrás log-vĂzhozam görbĂ©jĂ©nek törĂ©spontjai segĂtsĂ©gĂ©vel. | We tested the adequacy and power of dynamic factor analysis (DFA) in determining latent effects that shape the hydrographs of groundwater monitoring wells. Within the karstic environment, we extended the monitoring area of our previous project. We successfully applied DFA in sedimentary environments, other than karst. DFA provides a powerful indicator of the vulnerability of the aquifer by measuring the intensity of the major latent effects at a given location. In the Szigetköz area the changes of the factor loadings trace back the migration of water supply from Danube into the aquifer caused by the construction of the BĹ‘s dam. We gave two important models for diurnal discharge time series of rivers, analysed the properties of their estimators, and fitted them to the data of Tisza and Danube. In the first model a generalised beta-ARCH type noise passes through an ARMA filter, whereas in the second a semi-Markov hidden regime indicator process governs the swithches of a gamma random walk and a Gaussian AR(1) process in the ascending and descending regimes. We analysed the extreme value properties of the models both in theory and by means of simulations, and compared it with the real data. The results were used in flood risk estimations for insurance companies. We determined the depletion-time of various crack-systems in the Aggtelek karst from the break-points of the log-runoff curves of 5 springs in the area
Effect of plasmapheresis on ligand binding capacity and expression of erythrocyte complement receptor type 1 (CR1) of patients with systemic lupus erythematosus (SLE)
The functional activity and the expression of CR1 on the erythrocytes (E) of patients with SLE were, respectively, determined by measuring the binding to E of either complement-opsonized bovine serum albumin (BSA)–anti-BSA immune complexes (ICC) or specific anti-ECR1 MoAbs. We found that both the functional activity and levels of ECR1 in SLE patients homozygous for ECR1 high density allele were significantly lowered compared with healthy controls having the same allele. Soon after plasmapheresis there was a significant increase in E ICC binding activity, and this increased functional activity was stable. Moreover, plasmapheresis reduced the level of immune complexes demonstrable in the circulation of the patients. The expression of ECR1 determined with several different anti-CR1 MoAbs was also elevated as a consequence of plasmapheresis. This elevation was observed for both MoAb 1B4, which competes for the ICC binding site of ECR1, and for MoAb HB8592, which does not, but the time course for the increase in binding of the two MoAbs was different, in that the epitope recognized by MoAb 1B4 increased more rapidly. The present results, considered in the context of previous findings, suggest that more than one mechanism may be operative with respect to the effects of the plasmapheresis in increasing ECR1 levels defined by different epitopes on the molecule