Patient perspectives and experiences of remote consultations in people receiving kidney care: A scoping review

Background: The COVID-19 pandemic resulted in a rapid and sometimes chaotic change in how clinical care was delivered for people living with kidney disease, with increased reliance on digital technologies and the introduction of remote services. Objective: To conduct a scoping review of studies about peoples’ experiences and perspectives in receipt of remote consultations for kidney care. Methods: Using Arksey and O’Malley’s (2005) framework, three databases (CINAHL, MEDLINE, and PsycINFO) were searched simultaneously on EBSCO The search included studies published in English from August 2010 to August 2021. Results: Eight cross-sectional studies met the scoping review criteria (two quantitative, two mixed-method, and four qualitative). Four themes were identified: overall satisfaction with remote services, benefits to patients (convenience, involvement in care, and patient safety), barriers to remote consultations (technical difficulties, digital literacy, loss of interpersonal communication, existing patient-practitioner relationship, and access to technology), and patients’ concerns (need for physical examination, privacy, and confidentiality). Conclusion: Remote consultations confer multiple advantages to patients; therefore, remote consultations should be offered as an option to patients living with kidney disease beyond the COVID-19 pandemic. However, there are several barriers to remote consultation that need to be addressed and understood before implementing remote care long-term. Future research should examine the impact of remote consultations on people living with kidney disease from under-served groups to identify barriers and ensure their suitability and accessibility to the wider population for a more patient-centred approach to kidney care

Spectral line shape of resonant four-wave mixing induced by broad-bandwidth lasers

We present a theoretical and experimental study of the line shape of resonant four-wave mixing induced by broad-bandwidth laser radiation that revises the theory of Meacher, Smith, Ewart, and Cooper (MSEC) [Phys. Rev. A 46, 2718 (1992)]. We adopt the same method as MSEC but correct for an invalid integral used to average over the distribution of atomic velocities. The revised theory predicts a Voigt line shape composed of a homogeneous, Lorentzian component, defined by the collisional rate Γ, and an inhomogeneous, Doppler component, which is a squared Gaussian. The width of the inhomogeneous component is reduced by a factor of √2 compared to the simple Doppler width predicted by MSEC. In the limit of dominant Doppler broadening, the width of the homogeneous component is predicted to be 4Γ, whereas in the limit of dominant homogeneous broadening, the predicted width is 2Γ. An experimental measurement is reported of the line shape of the four-wave-mixing signal using a broad-bandwidth, "modeless", laser resonant with the Q1 (6) line of the A2 Σ - X2 Π(0,0) system of the hydroxyl radical. The measured widths of the Voigt components were found to be consistent with the predictions of the revised theory

The effects of light pruning, irrigation and improved soil management on wine quality of the Vitis vinifera cv. Riesling

A number of yield improving viticultural practices were assessed in terms of their effect on wine quality. These were improved soil management, lighter pruning/higher trellis, irrigation and a control. In the first year a yield increase of 1.6 t /ha for the irrigation treatment had no significant effect on wine quality. A procedure is presented to assess judges for reliability, discrimination, variability and stability as part of analysis of the sensory results. Four judges were able to consistently identify lot differences

Cognitive representations of disability behaviours in people with mobility limitations : consistency with theoretical constructs

Disability is conceptualised as behaviour by psychological theory and as a result of bodily impairment by medical models. However, how people with disabilities conceptualise those disabilities is unclear. The purpose of this study was to examine disability representations in people with mobility disabilities. Thirteen people with mobility disabilities completed personal repertory grids (using the method of triads) applied to activities used to measure disabilities. Ten judges with expertise in health psychology then examined the correspondence between the elicited disability constructs and psychological and medical models of disability. Participants with mobility disabilities generated 73 personal constructs ofdisability. These constructs were judged consistent with the content of two psychological models, namely the theory of planned behaviour and social cognitive theory and with the main medical model of disability, the International Classification of Functioning Disability and Health.Individuals with activity limitations conceptualise activities in a manner that is compatible with both psychological and medical models. This ensures adequate communication in contexts where the medical model is relevant, e.g. clinical contexts, as well as in everyday conversation about activities and behaviours. Finally, integrated models of disability may be of value for theory driven interdisciplinary approaches to disability and rehabilitation

Empirical Evaluation of Oligonucleotide Probe Selection for DNA Microarrays

DNA-based microarrays are increasingly central to biomedical research. Selecting oligonucleotide sequences that will behave consistently across experiments is essential to the design, production and performance of DNA microarrays. Here our aim was to improve on probe design parameters by empirically and systematically evaluating probe performance in a multivariate context. We used experimental data from 19 array CGH hybridizations to assess the probe performance of 385,474 probes tiled in the Duchenne muscular dystrophy (DMD) region of the X chromosome. Our results demonstrate that probe melting temperature, single nucleotide polymorphisms (SNPs), and homocytosine motifs all have a strong effect on probe behavior. These findings, when incorporated into future microarray probe selection algorithms, may improve microarray performance for a wide variety of applications

Promotion of the Etendeka Formation to Group status: a new integrated stratigraphy

The Etendeka volcanic rocks of northwestem Namibia are currently defined as the upper part of the Karoo Sequence in Namibia and have thus been represented as stratigraphically equivalent to the volcanic rocks of the Karoo Sequence in South Africa, Botswana, Lesotho, Swaziland and Zimbabwe. However, the Etendeka volcanic rocks (130-135 Ma) are considerably younger than those of the Karoo Sequence (180-190 Ma) in the areas mentioned above. They are compositionally distinct from Karoo volcanic rocks, and constitute an eastern portion of the Parana Igneous Province of Brazil. Stratigraphic studies have shown the Etendeka Formation to be made up of several definable volcanic successions and it is suggested that these successions now be formally recognized as Formations within an Etendeka Group which itself should no longer be part of the Karoo Sequence. Prominent quartz latite units and sequences of basalt flows are defined as Members within the new Formations

Visuo-spatial cognition in Williams syndrome: Reviewing and accounting for the strengths and weaknesses in performance

Individuals with Williams syndrome typically show relatively poor visuo-spatial abilities in comparison to stronger verbal skills. However, individuals' level of performance is not consistent across all visuo-spatial tasks. The studies assessing visuo-spatial functioning in Williams syndrome are critically reviewed, in order to provide a clear pattern of the relative difficulty of these tasks. This prompts a possible explanation of the variability in performance seen which focuses on the processing demands of some of these tasks. Individuals with Williams syndrome show an atypical processing style on tests of construction, which does not affect tests of perception