Altai centre of science«thermosynthesis» on high-temperature synthesis of new materials. Condition and prospects

Achievements of problem research laboratory SHS-material science founded in 1992 on the basis of I.I. Polzunov Altai State Technical University have been state

On Zermelo's theorem

A famous result in game theory known as Zermelo's theorem says that "in chess either White can force a win, or Black can force a win, or both sides can force at least a draw". The present paper extends this result to the class of all finite-stage two-player games of complete information with alternating moves. It is shown that in any such game either the first player has a winning strategy, or the second player has a winning strategy, or both have unbeatable strategies

Energy analysis of non-covalent ligand binding to nucleic acids: Present and future

Generalization of current views on energy analysis of complex formation of biologically active compounds with nucleic acids is represented and the outlook for further developments is determine

Theoretical description of metabolism using queueing theory

A theoretical description of the process of metabolism has been developed on the basis of the Pachinkomodel (seeNicholson andWilson in Nat Rev Drug Discov 2:668–676, 2003) and the queueing theory. The suggested approach relies on the probabilistic nature of the metabolic events and the Poisson distribution of the incoming flowof substratemolecules.The main focus of thework is an output flowofmetabolites or the effectiveness of metabolism process. Two simplest models have been analyzed: short- and long-living complexes of the source molecules with a metabolizing point (Hole) without queuing. It has been concluded that the approach based on queueing theory enables a very broad range of metabolic events to be described theoretically from a single probabilistic point of vie

General statistical-thermodynamical treatment of one-dimensional multicomponent molecular hetero-assembly in solution

A general treatment has been developed for the multicomponent one-dimensional non-covalent molec-ular hetero-assembly in solution using transfer matrix and sequence generating function approaches. The main result is set of equations, which allows one to obtain any thermodynamical quantities of the mul-ticomponent system and, in particular, experimental observable enabling one to get all equilibrium parameters of molecular interaction. The matrix form of presentation of the key equations allows their direct incorporation into matrix-oriented mathematical software, which leads to a two orders of magni-tude increase in speed of calculation of as compared to other known approache

Efficiency of using East Kazakhstan natural sorbents in water purification from ions of heavy metals (Cu2+)

Sorption properties of bentonite clays of East Kazakhstan have been studied by the example of model solutions containing ions of copper (Cu2+). The mechanism of exchange and degree of ion extraction from solutions were establishe

General features of the energetics of complex formation between ligand and nucleic acids

The analysis of the energy contributions of various physical factors to the complex formation between biologically active compounds and nucleic acids in aqueous solution was performed. A comparison of the energy parameters was made for ligand-ligand, intercalator-DNA, MGB-DNA and ligand-RNA groups. It was shown that the energetics of these reactions is of compensatory nature. Physical factors exerting the most pronounced influence on the energy parameters were identified. Correlation of the energy contributions to MGB-DNA complex formation and its biological effect was foun

Calculation of stationary electric fields in quasi-homogeneous media of multi-electrode composite electric radiators

Theoretical bases of calculation of stationary electric fields parameters in quasi-homogeneous media of multi-electrode composite electric radiators on the basis of methods of direct determination of field intensity and conformal transformations have been given. The calculated models, exact and approximate formulas necessary for determining electric conductivity of various electric radiators are offered. Experimental acknowledgement of quasi-homogeneity of resistive layer by specific electrical conductivity is give