Additive sustainability footprint: Rationale and pilot evaluation of a tool for assessing the sustainable use of PVC additives

© 2019 The Authors. Journal of Vinyl and Additive Technology published by Wiley Periodicals, Inc. on behalf of Society of Plastics Engineers. PVC compounds contain additives necessary for processing and stability, and to modify the plastic's properties. The Europe-wide VinylPlus® voluntary commitment includes a challenge to make progress toward sustainable use of additives. Additive Sustainability Footprint (ASF) was developed to assess sustainable use of additives across the whole societal life cycles of finished PVC articles, taking a risk-based approach rather than simplistic hazard assessment. ASF addresses impacts across six life cycle assessment (LCA) stages established by ISO Standard 14040, using the four System Conditions (sustainability principles) developed by The Natural Step (TNS) covering social as well as environmental factors. For each LCA stage/System Condition combination, seven generically similar questions cover negative impacts (many covered by existing tools and regulations) but also the additive's positive contributions to the sustainability of finished articles. Positive contributions include ethical sourcing, longevity of service life, low maintenance inputs, and recyclability. Answers to questions determine a score, which can be combined across the life cycle and with other additives. Testing on a generic EU PVC window profile supported ASF development and demonstrated applicability and potential benefits including use for sensitivity analysis of alternative additives from different geopolitical regions or from recycled as opposed to virgin sources. J. VINYL ADDIT. TECHNOL., 2019. © 2019 The Authors. Journal of Vinyl and Additive Technology published by Wiley Periodicals, Inc. on behalf of Society of Plastics Engineers

Improved lung function and body mass index associated with long-term use of Macrolide antibiotics

AbstractBackground: A number of studies have suggested that the non-antimicrobial actions of macrolide antibiotics may be valuable in treating patients with cystic fibrosis. The use of long-term macrolide antibiotics for the management of CF patients colonised by Pseudomonas aeruginosa and progressive pulmonary disease was introduced into our clinic in 1997. A retrospective study was undertaken to assess of the impact of this therapy. Methods: Twenty patients with progressive pulmonary disease (>10% fall in FEV1 over 12 months despite optimising conventional therapy) were commenced on Azithromycin, 250 mg daily during a 21-month period. At the time of assessment they had remained on therapy for a mean of 0.9 years. Changes in lung function, weight, body mass index (BMI) and frequency of pulmonary exacerbations were assessed. A group of 20 patients with stable lung function and matched as far as possible for age and sex was identified for comparison. Results: Pulmonary function increased significantly in the Azithromycin group with FEV1% predicted increasing from a mean of 50.2–59.1% (P=0.001) while FVC% predicted increase from 64.5 to 76.1% (P=0.002). There was small but non-significant fall in lung function in the comparison group. Body mass index increased by a mean of 1.1 in the Azithromycin group but remained unchanged in the comparison group. The number of pulmonary exacerbations requiring intravenous antibiotics declined by 48.3% in macrolide treated subjects compared to the pre-treatment period (P<0.025); frequency of exacerbations in the control group was unchanged. Conclusion: Long-term Azithromycin treatment in patients with progressive deterioration in lung function appears to have led to an improvement in pulmonary function, increased body mass index and decreased the frequency of pulmonary exacerbations requiring intravenous antibiotics

Twenty Years of the Polyvinyl Chloride Sustainability Challenges

Intense campaigning pressure on the UK PVC sector up to the late 1990s forced strategic engagement with sustainable development. Simplified outcomes from a detailed, consensus-based analysis by science-based NGO The Natural Step (TNS) took the form of five TNS Sustainability Challenges for PVC published in 2000. UK manufacturing companies initially used these Challenges to direct strategic progress. The Challenges have since been progressively taken up across European PVC value chains. The VinylPlus® programme uses an updated version of the five Challenges as a basis for voluntary commitments and transparent auditing of progress against published targets. Initial framing of the five TNS Sustainability Challenges for PVC were drafted consciously for generic relevance to other materials. Assessing the sustainability performance of some alternative materials to PVC against the five Sustainability Challenges reveals different sustainability performance in a range of potential applications. This highlights the danger inherent in automatic selection or deselection of materials in the absence of assessment of options on a ‘level playing field’ of sustainability principles. The five TNS Sustainability Challenges for PVC remain valid today and into the longer-term future as a basis for making stepwise, profitable progress towards the goal of sustainability for PVC and other materials

Building capacity for co-operative governance as a basis for integrated water resource managing in the Inkomati and Mvoti catchments, South Africa

South Africa’s National Water Act and National Water Resource Strategy set out an ambitious vision for Integrated Water Resources Management including a strong focus on the redistribution of water resources towards the poor and on empowering historically disadvantaged communities. To achieve this vision the Department of Water Affairs &amp; Forestry (DWAF) has been pursuing a programme for devolving powers to 19 stakeholder-led catchment management agencies (CMAs) and more locally, transforming irrigation boards into more inclusive water user associations (WUAs), as well as creating new associations.Co-operative governance is a core principle of this programme. As well as being enshrined in South Africa’s constitution, this principle is seen as key to enabling CMAs to implement their core functions, which include co-ordinating the activities of water users and water management institutions within their water management area. For WUAs also, the principle of co-operative governance is key to building engagement between White commercial farmers and emerging Black farmers, as well as (in some cases) engaging with a wider set of stakeholder interests including local government and environmental interests.Despite a commitment to the principle of co-operative governance, individual and institutional capacity for facilitating co-operative development processes is in relatively short supply within the South African water sector. This paper describes work-in-progress to build capacity in this area, working with:• DWAF’s national Institutional Governance team• The Inkomati CMA (ICMA), the first of South Africa’s new catchment management agencies• Two irrigation boards and a number of other stakeholders in the Mvoti catchment – with a view to the development of an appropriate institutional arrangement (WUA or otherwise) for the co-operative governance of this catchment.This paper focuses on the development of an interactive approach to capacity building in each of these three sites, drawing from a broad portfolio of approaches variously described as social learning, social appraisal, or whole system development. In the Inkomati we have worked primarily with the whole system approach known as Future Search, whereas in the Mvoti we have used the U-process and social appraisal as guiding metaphors and design principles.This paper describes some of our achievements, challenges and reflections to date, and argues that the interactive approaches we have been taking are better suited to the implementation of DWAF’s institutional reform processes than the more established, top-down approaches, which involve issuing guidance, supported by training programmes. The paper concludes with a discussion of the implications for scaling up these types of approaches across the South African water system as a whole, and for the practice of integrated water resource management.Keywords: adaptive IWRM, catchment management agencies, cooperative governance, dialogue, interactive capacity building, social learning, water user association