Flavour Universal Dynamical Electroweak Symmetry Breaking

The top condensate see-saw mechanism of Dobrescu and Hill allows electroweak symmetry to be broken while deferring the problem of flavour to an electroweak singlet, massive sector. We provide an extended version of the singlet sector that naturally accommodates realistic masses for all the standard model fermions, which play an equal role in breaking electroweak symmetry. The models result in a relatively light composite Higgs sector with masses typically in the range of (400-700)~GeV. In more complete models the dynamics will presumably be driven by a broken gauged family or flavour symmetry group. As an example of the higher scale dynamics a fully dynamical model of the quark sector with a GIM mechanism is presented, based on an earlier top condensation model of King using broken family gauge symmetry interactions (that model was itself based on a technicolour model of Georgi). The crucial extra ingredient is a reinterpretation of the condensates that form when several gauge groups become strong close to the same scale. A related technicolour model of Randall which naturally includes the leptons too may also be adapted to this scenario. We discuss the low energy constraints on the massive gauge bosons and scalars of these models as well as their phenomenology at the TeV scale.Comment: 22 pages, 3 fig

Fluctuation Theorems for Entropy Production and Heat Dissipation in Periodically Driven Markov Chains

Asymptotic fluctuation theorems are statements of a Gallavotti-Cohen symmetry in the rate function of either the time-averaged entropy production or heat dissipation of a process. Such theorems have been proved for various general classes of continuous-time deterministic and stochastic processes, but always under the assumption that the forces driving the system are time independent, and often relying on the existence of a limiting ergodic distribution. In this paper we extend the asymptotic fluctuation theorem for the first time to inhomogeneous continuous-time processes without a stationary distribution, considering specifically a finite state Markov chain driven by periodic transition rates. We find that for both entropy production and heat dissipation, the usual Gallavotti-Cohen symmetry of the rate function is generalized to an analogous relation between the rate functions of the original process and its corresponding backward process, in which the trajectory and the driving protocol have been time-reversed. The effect is that spontaneous positive fluctuations in the long time average of each quantity in the forward process are exponentially more likely than spontaneous negative fluctuations in the backward process, and vice-versa, revealing that the distributions of fluctuations in universes in which time moves forward and backward are related. As an additional result, the asymptotic time-averaged entropy production is obtained as the integral of a periodic entropy production rate that generalizes the constant rate pertaining to homogeneous dynamics

Interaction of artesunate with β-cyclodextrin: Characterization, thermodynamic parameters, molecular modeling, effect of PEG on complexation and antimalarial activity

AbstractInclusion of artesunate in the cavity of β-cyclodextrin (β-CD) as well as its methyl and hydroxypropyl derivatives was investigated experimentally and by molecular modeling studies. The effect of PEG on the inclusion was also studied. A 1:1 stoichiometry was indicated by phase-solubility studies both in the presence and absence of PEG and suggested by the mass spectrometry. The mode of inclusion was supported by 2D NMR and results were further verified by docking studies utilizing Fast Rigid Exhaustive Docking acronym. The thermodynamic parameters were determined for both binary and ternary systems using solution calorimetry and were found to be best for the methyl-β-cyclodextrin (Me-β-CD) system. However, the presence of PEG improves the complexation ability as evident from elevation in the numerical value of the stability constant (K). Solubility and dissolution profile of binary complex is enhanced in the presence of PEG, which is approximately at par with drug Me-β-CD complexes. In vivo studies showed 100% survivability in artesunate–Me-β-CD complexes

Four Dimensional Integrable Theories

There exist many four dimensional integrable theories. They include self-dual gauge and gravity theories, all their extended supersymmetric generalisations, as well the full (non-self-dual) N=3 super Yang-Mills equations. We review the harmonic space formulation of the twistor transform for these theories which yields a method of producing explicit connections and metrics. This formulation uses the concept of harmonic space analyticity which is closely related to that of quaternionic analyticity. (Talk by V. Ogievetsky at the G\"ursey Memorial Conference I, Istanbul, June 1994)Comment: 11 pages, late

On the dynamical behavior of the ABC model

We consider the ABC dynamics, with equal density of the three species, on the discrete ring with $N$ sites. In this case, the process is reversible with respect to a Gibbs measure with a mean field interaction that undergoes a second order phase transition. We analyze the relaxation time of the dynamics and show that at high temperature it grows at most as $N^2$ while it grows at least as $N^3$ at low temperature

A Framework for Supervision for Mindfulness-Based Teachers:a Space for Embodied Mutual Inquiry

Over recent decades, there has been an exponential growth in mindfulness-based interventions (MBIs). To disseminate MBIs with fidelity, care needs to be taken with the training and supervision of MBI teachers. A wealth of literature exists describing the process and practice of supervision in a range of clinical approaches, but, as of yet, little consideration has been given to how this can best be applied to the supervision of MBI teachers. This paper articulates a framework for supervision of MBI teachers. It was informed by the following: the experience of eight experienced mindfulness-based supervisors, the literature and understandings from MBIs, and by the authors’ experience of training and supervision. It sets out the nature and distinctive features of mindfulness-based supervision (MBS), representing this complex, multilayered process through a series of circles that denote its essence, form, content and process. This paper aims to be a basis for further dialogue on MBS, providing a foundation to increase the availability of competent supervision so that MBIs can expand without compromising integrity and efficacy

Deflection of coronal rays by remote CMEs: shock wave or magnetic pressure?

We analyze five events of the interaction of coronal mass ejections (CMEs) with the remote coronal rays located up to 90^\circ away from the CME as observed by the SOHO/LASCO C2 coronagraph. Using sequences of SOHO/LASCO C2 images, we estimate the kink propagation in the coronal rays during their interaction with the corresponding CMEs ranging from 180 to 920 km/s within the interval of radial distances form 3 R. to 6 R. . We conclude that all studied events do not correspond to the expected pattern of shock wave propagation in the corona. Coronal ray deflection can be interpreted as the influence of the magnetic field of a moving flux rope related to a CME. The motion of a large-scale flux rope away from the Sun creates changes in the structure of surrounding field lines, which are similar to the kink propagation along coronal rays. The retardation of the potential should be taken into account since the flux rope moves at high speed comparable with the Alfven speed.Comment: Accepted for Publication in Solar Physic

Ferromagnetic models for cooperative behavior: Revisiting Universality in complex phenomena

Ferromagnetic models are harmonic oscillators in statistical mechanics. Beyond their original scope in tackling phase transition and symmetry breaking in theoretical physics, they are nowadays experiencing a renewal applicative interest as they capture the main features of disparate complex phenomena, whose quantitative investigation in the past were forbidden due to data lacking. After a streamlined introduction to these models, suitably embedded on random graphs, aim of the present paper is to show their importance in a plethora of widespread research fields, so to highlight the unifying framework reached by using statistical mechanics as a tool for their investigation. Specifically we will deal with examples stemmed from sociology, chemistry, cybernetics (electronics) and biology (immunology).Comment: Contributing to the proceedings of the Conference "Mathematical models and methods for Planet Heart", INdAM, Rome 201

On the fluctuations of jamming coverage upon random sequential adsorption on homogeneous and heterogeneous media

The fluctuations of the jamming coverage upon Random Sequential Adsorption (RSA) are studied using both analytical and numerical techniques. Our main result shows that these fluctuations (characterized by $\sigma_{\theta_J}$) decay with the lattice size according to the power-law $\sigma_{\theta_J} \propto L^{-1/ \nu}$. The exponent $\nu$ depends on the dimensionality $D$ of the substrate and the fractal dimension of the set where the RSA process actually takes place ($d_f$) according to $\nu = 2 / (2D - d_f)$.This theoretical result is confirmed by means of extensive numerical simulations applied to the RSA of dimers on homogeneous and stochastic fractal substrates. Furthermore, our predictions are in excellent agreement with different previous numerical results. It is also shown that, studying correlated stochastic processes, one can define various fluctuating quantities designed to capture either the underlying physics of individual processes or that of the whole system. So, subtle differences in the definitions may lead to dramatically different physical interpretations of the results. Here, this statement is demonstrated for the case of RSA of dimers on binary alloys.Comment: 20 pages, 8 figure

Phase diagram of the ABC model on an interval

The three species asymmetric ABC model was initially defined on a ring by Evans, Kafri, Koduvely, and Mukamel, and the weakly asymmetric version was later studied by Clincy, Derrida, and Evans. Here the latter model is studied on a one-dimensional lattice of N sites with closed (zero flux) boundaries. In this geometry the local particle conserving dynamics satisfies detailed balance with respect to a canonical Gibbs measure with long range asymmetric pair interactions. This generalizes results for the ring case, where detailed balance holds, and in fact the steady state measure is known only for the case of equal densities of the different species: in the latter case the stationary states of the system on a ring and on an interval are the same. We prove that in the N to infinity limit the scaled density profiles are given by (pieces of) the periodic trajectory of a particle moving in a quartic confining potential. We further prove uniqueness of the profiles, i.e., the existence of a single phase, in all regions of the parameter space (of average densities and temperature) except at low temperature with all densities equal; in this case a continuum of phases, differing by translation, coexist. The results for the equal density case apply also to the system on the ring, and there extend results of Clincy et al.Comment: 52 pages, AMS-LaTeX, 8 figures from 10 eps figure files. Revision: minor changes in response to referee reports; paper to appear in J. Stat. Phy