68 research outputs found
Simulation des écoulements à surface libre dans les turbines Pelton par une méthode hybride SPH-ALE
International audienceAn Arbitrary Lagrange Euler (ALE) description of fluid flows is used together with the meshless numerical method Smoothed Particle Hydrodynamics (SPH) to simulate free surface flows. The ALE description leads to an hybrid method that can be closely connected to the finite volume approach. It is then possible to adapt some common techniques like upwind schemes and preconditioning to remedy some of the well known drawbacks of SPH like stability and accuracy. An efficient boundary treatment based on a proper upwinding of fluid information at the boundary surface is settled. The resulting SPH-ALE numerical method is applied to simulate free surface flows encountered in Pelton turbines.La méthode numérique sans maillage Smoothed Particle Hydrodynamics (SPH) est modifiée par l'adoption d'une description Arbitrary Lagrange Euler (ALE) des écoulements fluides, dans le but de simuler des écoulements à surface libre. Le formalisme ALE conduit à une méthode numérique hybride s'apparentant sur de nombreux points à une approche volumes finis. Il est alors possible d'adapter des techniques numériques courantes comme les schémas décentrés et le préconditionnement pour résoudre certains défauts majeurs de la méthode SPH, comme la stabilité numérique ou le manque de précision. Par ailleurs, le traitement des conditions limites est réalisé par un décentrement approprié des informations fluides sur les surfaces frontières. La méthode numérique SPH-ALE résultante est appliquée à la simulation d'écoulements à surface libre tels que ceux rencontrés dans les turbines Pelton
Simulation des écoulements à surface libre dans les turbines Pelton par une méthode hybride SPH-ALE
International audienceAn Arbitrary Lagrange Euler (ALE) description of fluid flows is used together with the meshless numerical method Smoothed Particle Hydrodynamics (SPH) to simulate free surface flows. The ALE description leads to an hybrid method that can be closely connected to the finite volume approach. It is then possible to adapt some common techniques like upwind schemes and preconditioning to remedy some of the well known drawbacks of SPH like stability and accuracy. An efficient boundary treatment based on a proper upwinding of fluid information at the boundary surface is settled. The resulting SPH-ALE numerical method is applied to simulate free surface flows encountered in Pelton turbines.La méthode numérique sans maillage Smoothed Particle Hydrodynamics (SPH) est modifiée par l'adoption d'une description Arbitrary Lagrange Euler (ALE) des écoulements fluides, dans le but de simuler des écoulements à surface libre. Le formalisme ALE conduit à une méthode numérique hybride s'apparentant sur de nombreux points à une approche volumes finis. Il est alors possible d'adapter des techniques numériques courantes comme les schémas décentrés et le préconditionnement pour résoudre certains défauts majeurs de la méthode SPH, comme la stabilité numérique ou le manque de précision. Par ailleurs, le traitement des conditions limites est réalisé par un décentrement approprié des informations fluides sur les surfaces frontières. La méthode numérique SPH-ALE résultante est appliquée à la simulation d'écoulements à surface libre tels que ceux rencontrés dans les turbines Pelton
Experimental and Numerical Analysis or Free Surface Flows in a Rotating Bucket
The aim of this study was to provide a complete experimental and numerical analysis of the flow in a rotating Pelton bucket. For the experimental analysis, several functioning points have been used in order to study differences which may occur in various situations. This analysis will be mainly provided by the pressure distribution in the bucket and will be supported by flow visualisations. Thanks to these results, five distinct zones within the bucket have been isolated each corresponding to different signal characteristics. The numerical simulation has been performed using the two-phase homogeneous method in an original way by considering the relative path of the jet and the relative velocity changing with the rotation of the wheel. These simulations were performed for the same experimental functioning points
Teachings research of lithalsas on Lidar images. Documents of the scientific station of the Hautes Fagnes
Pissart (2010) published a synthetic map locating high "viviers" (fishponds) areas in the Ardennes (Belgium), some of which were identified in the 1950s' on aerial photographs taken by aircraft flying at low altitude; others have been found on Google Earth in the 2000s'. However, be aware that one and the other source is usable for this purpose only in open landscapes. In 2015, the Public Service of Wallonia, via his site "WalOnMap" launches the Lidar mapping. Among other possibilities, this tool allows only restore the relief of the ground (digital field model), regardless of the plant cover (MNT 2013-2014 "Hillshade") . So the question is to estimate what can be the contribution of this new tool in the identification of traces of lithalsas
Comparison of Flow Computation Results with experimental Flow Surveys in a Francis Turbine
Three dimensional numerical tools are now commonly used in the design or analysis process of the internai flow of hydraulic machinery. As an illustration of the use of such tools to study the internai flow of a Francis turbine, the computational results obtained in all components of this turbine with an Euler equations solver and two Reynolds Averaged Navier Stokes equations solvers are discussed. The analysis process is illustrated and comparisons with experimental results obtained in the spiral casing and at the outlet of the guide vaoes, runner and draft tube are presented
Flow survey and blade pressure measurements in a Francis turbine model
Experimental flow analysis of hydraulic machines is of prime importance for improving the design of such a unit. Moreover, computational fluid dynamics codes need an experimental data reference in order to check their ability to simulate the main flow features. To obtain such an experimental data base a Francis turbine model and an associated instrumentation is specially developed. Measurements of both global and local quantities are performed for five different operating points of the turbine. A five-hole probe mounted on a remote displacement system provides static pressure and velocity components along three stations in the machine. An original rotating instrumentation is implemented in order to obtain the pressure distribution over the blades of the runner at 28 points ( 17 on the suction side and 11 on the pressure side) arranged along three streamlines
MetaQC: objective quality control and inclusion/exclusion criteria for genomic meta-analysis
Genomic meta-analysis to combine relevant and homogeneous studies has been widely applied, but the quality control (QC) and objective inclusion/exclusion criteria have been largely overlooked. Currently, the inclusion/exclusion criteria mostly depend on ad-hoc expert opinion or naïve threshold by sample size or platform. There are pressing needs to develop a systematic QC methodology as the decision of study inclusion greatly impacts the final meta-analysis outcome. In this article, we propose six quantitative quality control measures, covering internal homogeneity of coexpression structure among studies, external consistency of coexpression pattern with pathway database, and accuracy and consistency of differentially expressed gene detection or enriched pathway identification. Each quality control index is defined as the minus log transformed P values from formal hypothesis testing. Principal component analysis biplots and a standardized mean rank are applied to assist visualization and decision. We applied the proposed method to 4 large-scale examples, combining 7 brain cancer, 9 prostate cancer, 8 idiopathic pulmonary fibrosis and 17 major depressive disorder studies, respectively. The identified problematic studies were further scrutinized for potential technical or biological causes of their lower quality to determine their exclusion from meta-analysis. The application and simulation results concluded a systematic quality assessment framework for genomic meta-analysis
Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death
Functional telomeres are protected from non-homologous end-joining (NHEJ) and homologous recombination (HR) DNA repair pathways. Replication is a critical period for telomeres because of the requirement for reconstitution of functional protected telomere conformations, a process that involves DNA repair proteins. Using knockdown of DNA-PKcs and Rad51 expression in three different cell lines, we demonstrate the respective involvement of NHEJ and HR in the formation of telomere aberrations induced by the G-quadruplex ligand 360A during or after replication. HR contributed to specific chromatid-type aberrations (telomere losses and doublets) affecting the lagging strand telomeres, whereas DNA-PKcs-dependent NHEJ was responsible for sister telomere fusions as a direct consequence of G-quadruplex formation and/or stabilization induced by 360A on parental telomere G strands. NHEJ and HR activation at telomeres altered mitotic progression in treated cells. In particular, NHEJ-mediated sister telomere fusions were associated with altered metaphase-anaphase transition and anaphase bridges and resulted in cell death during mitosis or early G1. Collectively, these data elucidate specific molecular and cellular mechanisms triggered by telomere targeting by the G-quadruplex ligand 360A, leading to cancer cell death
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