CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Plant associations of cumbres de Majalca National Park, Chihuahua, Mexico

Vegetation types in Cumbres de Majalca National Park were classified using cluster analysis from 195 line transects and 975 1-m2 quadrats at 39 sites. Six plant associations emerged from oak-grassland and oak-conifer communities. Each association is described using cover, constancy, elevation, physiographic, and soil parameters. A vegetation profile and a map of the plant associations are presented

Flora del centro del estado de Chihuahua, México.

Se estudió la flora de las serranías y planicies de la porción central del estado de Chihuahua. Se realizaron 135 salidas de campo en un periodo de seis años, en los que se colectaron aproximadamente 6500 ejemplares botánicos, se recopiló la información bibliográfica sobre el tema y se revisó el material botánico de la región de estudio depositado en los herbarios ANSM, CFNL y TEX-LL. Se registró un total de 112 familias, 493 géneros, 1322 especies y 232 categorías infraespecíficas de plantas vasculares. Del total de familias, 87 corresponden a dicotiledóneas, 15 a monocotiledóneas, 7 a helechos y afines, y 3 a coníferas y afines. Las familias con mayor número de géneros y especies respectivamente son: Asteraceae (86, 235), Poaceae (50, 163), Leguminosae (45, 137), Brassicaceae (16, 25), Malvaceae (12, 29), Scrophulariaceae (11, 29), Cactaceae (10, 30), Verbenaceae (10, 24), Nyctaginaceae (7, 21) y Amaranthaceae (7, 18). Los géneros con mayor número de especies son Muhlenbergia (37), Dalea (22), Euphorbia (21), Cheilanthes (19), Brickellia (17), Salvia (15), Cyperus (14), Quercus (13), Solanum (12), Eragrostis (12), Bouteloua (12), Erigeron (12), Astragalus (11), Ipomoea (11), Plantago (10), Acacia (10), Machaeranthera (9), Stevia (9), Opuntia (9), Aristida (9), Asclepias (9), Phaseolus (9), Oenothera (9), Viguiera (9) y Notholaena (9). El presente estudio es una contribución hacia un mejor conocimiento de la diversidad vegetal que existe en las regiones áridas del norte de México