8 research outputs found

    Enseñando ajedrez a niños con dibujos animados

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    Esta tesina profesional trata sobre la creación de una pieza audiovisual con el objeto de familiarizar a niños de cuatro años con el ajedrez. En ella se explica detalladamente todos los contenidos que se han realizado en las distintas etapas de preproducción, producción y postproducción. La idea clave del proyecto es la adaptación de la animación a una estética dirigida a un público infantil, mediante el diseño de dibujos animados en 2D, empleando los conocimientos aprendidos en el máster de Postproducción digital.This professional thesis is about the creation of an audiovisual piece in order to familiarize four years children with chess. It explains in detail all the contents that have been made in different stages of preproduction, production and postproduction. The key idea of the project is the adaptation of animation to an aesthetics focused at children, by designing in 2D cartoons using the knowledge learned in the master of digital postproduction.Estévez Montero, R. (2015). Enseñando ajedrez a niños con dibujos animados. Universitat Politècnica de València. http://hdl.handle.net/10251/56795TFG

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Aprende Ajedrez con Rey - Parte 2

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    Es una pieza audiovisual creada con el objeto de atraer la atención de los niños de muy corta edad con el ajedrez y familiarizarlos con todas sus piezas y movimientos. Es una animación dirigida a un público infantil presentada por dibujos animados en 2D, en la que se ha intentado respetar en todo momento el argot de la comunidad ajedredística. En este video se presenta la segunda parte.Estévez Montero, R.; Lloret Mauri, J. (2016). Aprende Ajedrez con Rey - Parte 2. http://hdl.handle.net/10251/60825

    Enroque

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    Es una pieza audiovisual creada con el objeto de que los niños de muy corta edad apreanda a jugar a ajedrez y se familiaricen con las piezas y sus movimientos. Es una animación dirigida a un público infantil presentada por dibujos animados en 2D, en la que se ha intentado respetar en todo momento el argot de la comunidad ajedredística. En este video se explica cómo se enroca.Estévez Montero, R.; Lloret Mauri, J. (2017). Aprende Ajedrez con Rey. El Enroque. http://hdl.handle.net/10251/76559

    APRÈN AMB REI - Part 1

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    És una peça audiovisual creada amb l'objecte d'atreure l'atenció dels xiquets i xiquetes de molt curta edat als escacs i familiaritzar-los amb totes les peces i moviments. És una animació dirigida a un públic infantil presentada per dibuixos animats en 2D, en la qual s'ha intentat respectar en tot moment l'argot de la comunitat dels escacs. En aquest vídeo es presenta la primera part.Estévez Montero, R.; Lloret Mauri, J. (2016). APRÈN AMB REI - Part 1. http://hdl.handle.net/10251/71521

    ACR. Empezamos a Jugar - Parte 1

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    Es una pieza audiovisual creada con el objeto de que los niños de muy corta edad apreanda a jugar a ajedrez y se familiaricen con las piezas y sus movimientos. Es una animación dirigida a un público infantil presentada por dibujos animados en 2D, en la que se ha intentado respetar en todo momento el argot de la comunidad ajedredística. En este video se presenta la primera parte de aprendamos a jugar.Estévez Montero, R.; Lloret Mauri, J. (2016). Aprende Ajedrez con Rey. Empezamos a Jugar - Parte 1. http://hdl.handle.net/10251/71599

    Antioxidant Capacity through Electrochemical Methods and Chemical Composition of <i>Oenocarpus bataua</i> and <i>Gustavia macarenensis</i> from the Ecuadorian Amazon

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    This study evaluated the antioxidant properties and chemical composition of the seeds, pulp and peels of Ungurahua (Oenocarpus bataua) and Pasu (Gustavia macarenensis)—fruits, native to the Ecuadorian Amazon. The antioxidant capacity was measured by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and cyclic voltammetry (antioxidant index 50 (AI50)) assays; differential pulse voltammetry was used to evaluate antioxidant power using the electrochemical index. The total phenolic content, as well as the yellow flavonoid and anthocyanin content, were quantified via spectrophotometry. In addition, the trans-resveratrol and ascorbic acid content were evaluated through high performance liquid chromatography (HPLC). Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) was used to identify secondary metabolites with possible therapeutic properties. Results showed that the Pasu peel and seed extracts had the highest antioxidant capacity, followed by the Ungurahua peel; these results were consistent for both spectroscopic and electrochemical assays. HPLC and UPLC-MS analysis suggest that Oenocarpus bataua and Gustavia macarenensis are important sources of beneficial bioactive compounds

    Chemical composition and antioxidant properties of native Ecuadorian fruits: Rubus glabratus Kunth, Vaccinium floribundum Kunth, and Opuntia soederstromiana

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    The native berries of South America present promising marketing opportunities owing to their high antioxidant content, notably rich in anthocyanin and phenolic compounds. However, Ecuador's endemic fruits, primarily found in the wild, lack comprehensive data regarding their phytochemical composition and antioxidant capacity, underscoring the need for research in this area. Accordingly, this study evaluated the total phenolic, anthocyanin, flavonoid, resveratrol, ascorbic acid, citric acid, sugars, and antioxidant content of three native Ecuadorian fruits: mora de monte (Rubus glabratus Kunth), mortiño (Vaccinium floribundum Kunth), and tuna de monte (Opuntia soederstromiana). Determination of resveratrol, ascorbic acid, citric acid, and sugars was determined by HPLC analysis, and UPLC analysis was used to determine tentative metabolites with nutraceutical properties. Antioxidant capacity was assessed using cyclic voltammetry and the DPPH method; differential pulse voltammetry was used to evaluate antioxidant power. Analysis of results through UPLC-QTOF mass spectrometry indicated that R. glabratus Kunth and V. floribundum Kunth are important sources of various compounds with potential health-promoting functions in the body. The DPPH results showed the following antioxidant capacities for the three fruits: R. glabratus Kunth > O. soederstromiana > V. floribundum Kunth; this trend was consistent with the antioxidant capacity results determined using the electrochemical methods
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