High Enthalpy Ablation Testing at DLR Cologne

Testing thermal protection capabilities of ablative materials is one of the main working areas of DLR’s arc heated facilities LBK in Cologne. Work on this particular topic has been intensified about five years ago with the following major focus points: Significant improvement of the facilities testing capabilities with respect to cold wall heat flux rates and stagnation pressure. Ablation testing in Martian atmosphere. Influence of dust particle erosion on ablation

Modified Scaling Relation for the Random-Field Ising Model

We investigate the low-temperature critical behavior of the three dimensional random-field Ising ferromagnet. By a scaling analysis we find that in the limit of temperature $T \to 0$ the usual scaling relations have to be modified as far as the exponent $\alpha$ of the specific heat is concerned. At zero temperature, the Rushbrooke equation is modified to $\alpha + 2 \beta + \gamma = 1$, an equation which we expect to be valid also for other systems with similar critical behavior. We test the scaling theory numerically for the three dimensional random field Ising system with Gaussian probability distribution of the random fields by a combination of calculations of exact ground states with an integer optimization algorithm and Monte Carlo methods. By a finite size scaling analysis we calculate the critical exponents $\nu \approx 1.0$, $\beta \approx 0.05$, $\bar{\gamma} \approx 2.9$ $\gamma \approx 1.5$ and $\alpha \approx -0.55$.Comment: 4 pages, Latex, Postscript Figures include

Low-energy electronic properties of clean CaRuO3_3: elusive Landau quasiparticles

We have prepared high-quality epitaxial thin films of CaRuO$_3$ with residual resistivity ratios up to 55. Shubnikov-de Haas oscillations in the magnetoresistance and a $T^2$ temperature dependence in the electrical resistivity only below 1.5 K, whose coefficient is substantially suppressed in large magnetic fields, establish CaRuO$_3$ as a Fermi liquid (FL) with anomalously low coherence scale. Non-Fermi liquid (NFL) $T^{3/2}$ dependence is found between 2 and 25 K. The high sample quality allows access to the intrinsic electronic properties via THz spectroscopy. For frequencies below 0.6 THz, the conductivity is Drude-like and can be modeled by FL concepts, while for higher frequencies non-Drude behavior, inconsistent with FL predictions, is found. This establishes CaRuO$_3$ as a prime example of optical NFL behavior in the THz range.Comment: 12 pages, 21 figures including supplemental materia

Kinetics and isotype profile of antibody responses in rhesus macaques induced following vaccination with HPV 6, 11, 16 and 18 L1-virus-like particles formulated with or without Merck aluminum adjuvant

BACKGROUND: Human papillomaviruses (HPV) are the most common sexually transmitted viruses. Infection of the cervical epithelium by HPVs can lead to the development of cervical cancer. Recent advances in vaccine research have shown that immunization with papillomavirus-like particles (VLPs) containing the major structural viral protein, L1 from HPV 16 can provide protection from the establishment of a chronic HPV 16 infection and related cervical intraepithelial neoplasia (CIN) in baseline HPV 16 naïve women. METHODS: To better understand the quantitative and qualitative effects of aluminum adjuvant on the immunogenic properties of an HPV 6, 11, 16 and 18L1 VLP vaccine, we used an HPV-specific, antibody isotyping assay and a competitive immunoassay that measures antibodies to neutralizing epitopes to profile sera from rhesus macaques immunized with the HPV L1 VLP vaccine formulated with or without aluminum adjuvant. RESULTS: Immunization with VLPs formulated with the aluminum adjuvant elicited a significantly stronger immune response with higher peak antibody titers both at four weeks post vaccination (12.7 to 41.9-fold higher) as well as in the persistent phase at week 52 (4.3 to 26.7-fold higher) than that of VLPs alone. Furthermore, the aluminum adjuvant formulated HPV VLP vaccine elicited a predominantly T helper type 2 response, with high levels of IgG1 and IgG4 and low levels of IgG2. The vaccine also elicited high levels of serum IgA, which may be important in providing mucosal immunity to impart protection in the anogenital tract. CONCLUSION: These results show that the HPV 6, 11, 16 and 18 L1-VLP vaccine formulated with Merck aluminum adjuvant elicits a robust and durable immune response and holds promise as a vaccine for preventing cervical cancer

Dendritic cell reconstitution is associated with relapse-free survival and acute GVHD severity in children after allogeneic stem cell transplantation

DCs are potent APCs and key regulators of innate and adaptive immunity. After allo-SCT, their reconstitution in the peripheral blood (PB) to levels similar to those in healthy individuals tends to be slow. We investigate the age- and sex-dependant immune reconstitution of myeloid (mDC) and plasmacytoid DC (pDC) in the PB of 45 children with leukaemia or myelodysplastic syndrome (aged 1-17 years, median 10) after allo-SCT with regard to relapse, acute GVHD (aGVHD) and relapse-free survival. Low pDC/μL PB up to day 60 post SCT are associated with higher incidence of moderate or severe aGVHD (P=0.035), whereas high pDC/μL PB up to day 60 are associated with higher risk of relapse (P<0.001). The time-trend of DCs/μL PB for days 0-200 is a significant predictor of relapse-free survival for both mDCs (P<0.001) and pDCs (P=0.020). Jointly modelling DC reconstitution and complications improves on these simple criteria. Compared with BM, PBSC transplants tend to show slower mDC/pDC reconstitution (P=0.001, 0.031, respectively), but have no direct effect on relapse-free survival. These results suggest an important role for both mDCs and pDCs in the reconstituting immune system. The inclusion of mDCs and pDCs may improve existing models for complication prediction following allo-SCT

Class Attendance and Students’ Evaluations of Teaching: Do No-Shows Bias Course Ratings and Rankings?

Background: Many university departments use students’ evaluations of teaching (SET) to compare and rank courses. However, absenteeism from class is often nonrandom and, therefore, SET for different courses might not be comparable. Objective: The present study aims to answer two questions. Are SET positively biased due to absenteeism? Do procedures, which adjust for absenteeism, change course rankings? Research Design: The author discusses the problem from a missing data perspective and present empirical results from regression models to determine which factors are simultaneously associated with students’ class attendance and course ratings. In order to determine the extent of these biases, the author then corrects average ratings for students’ absenteeism and inspect changes in course rankings resulting from this adjustment. Subjects: The author analyzes SET data on the individual level. One or more course ratings are available for each student. Measures: Individual course ratings and absenteeism served as the key outcomes. Results: Absenteeism decreases with rising teaching quality. Furthermore, both factors are systematically related to student and course attributes. Weighting students’ ratings by actual absenteeism leads to mostly small changes in ranks, which follow a power law. Only a few, average courses are disproportionally influenced by the adjustment. Weighting by predicted absenteeism leads to very small changes in ranks. Again, average courses are more strongly affected than courses of very high or low in quality. Conclusions: No-shows bias course ratings and rankings. SET are more appropriate to identify high- and low-quality courses than to determine the exact ranks of average courses

Dynamics of Domains in Diluted Antiferromagnets

We investigate the dynamics of two-dimensional site-diluted Ising antiferromagnets. In an external magnetic field these highly disordered magnetic systems have a domain structure which consists of fractal domains with sizes on a broad range of length scales. We focus on the dynamics of these systems during the relaxation from a long-range ordered initial state to the disordered fractal-domain state after applying an external magnetic field. The equilibrium state with applied field consists of fractal domains with a size distribution which follows a power law with an exponential cut-off. The dynamics of the system can be understood as a growth process of this fractal-domain state in such a way that the equilibrium distribution of domains develops during time. Following these ideas quantitatively we derive a simple description of the time dependence of the order parameter. The agreement with simulations is excellent.Comment: Revtex, 6 pages, 5 Postscript figure

Polymer-Based Batteries — Flexible and Thin Energy Storage Systems

Batteries have become an integral part of everyday life—from small coin cells to batteries for mobile phones, as well as batteries for electric vehicles and an increasing number of stationary energy storage applications. There is a large variety of standardized battery sizes (e.g., the familiar AA‐battery or AAA‐battery). Interestingly, all these battery systems are based on a huge number of different cell chemistries depending on the application and the corresponding requirements. There is not one single battery type fulfilling all demands for all imaginable applications. One battery class that has been gaining significant interest in recent years is polymer‐based batteries. These batteries utilize organic materials as the active parts within the electrodes without utilizing metals (and their compounds) as the redox‐active materials. Such polymer‐based batteries feature a number of interesting properties, like high power densities and flexible batteries fabrication, among many more

Dimensional crossover in dipolar magnetic layers

We investigate the static critical behaviour of a uniaxial magnetic layer, with finite thickness L in one direction, yet infinitely extended in the remaining d dimensions. The magnetic dipole-dipole interaction is taken into account. We apply a variant of Wilson's momentum shell renormalisation group approach to describe the crossover between the critical behaviour of the 3-D Ising, 2-d Ising, 3-D uniaxial dipolar, and the 2-d uniaxial dipolar universality classes. The corresponding renormalisation group fixed points are in addition to different effective dimensionalities characterised by distinct analytic structures of the propagator, and are consequently associated with varying upper critical dimensions. While the limiting cases can be discussed by means of dimensional epsilon expansions with respect to the appropriate upper critical dimensions, respectively, the crossover features must be addressed in terms of the renormalisation group flow trajectories at fixed dimensionality d.Comment: 25 pages, Latex, 12 figures (.eps files) and IOP style files include