The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds differ considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African influence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confirm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development

The genetic ancestry of american creole cattle inferred from uniparental and autosomal genetic markers.

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds differ considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African influence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confirm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development

Situacion actual de las razas autoctonas andaluzas en peligro de extincion

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Influência do sexo do animal e do sistema de produção nas características de carcaça de caprinos da raça Blanca Serrana Andaluza Influence of animal gender and production system on the carcass characteristics of goats of the Blanca Serrana Andaluza breed

Objetivou-se avaliar a influência do sexo e do sistema de produção nas características de carcaça de caprinos da raça Blanca Serrana Andaluza. Foram utilizados 31 animais, 12 machos e 19 fêmeas, distribuídos nos sistemas de produção intensivo (15 animais) e extensivo (16 animais). Não foi observada diferença no desempenho, no peso de carcaça e no escore corporal entre os sexos nem entre os sistemas de produção, contudo, os rendimentos de carcaça quente e fria foram maiores nos animais terminados em confinamento. As medidas de carcaça não diferiram entre os sistemas de produção, exceto o comprimento interno, que foi maior nos animais criados no sistema intensivo. O percentual dos não-constituintes da carcaça sofreu pouca variação em relação ao sexo e aos sistemas de criação avaliados. As maiores proporções de gordura perirrenal foram encontradas nas fêmeas e nos animais produzidos em confinamento. Pouca variação foi observada para os cortes paleta, pescoço e serrote, embora o percentual de perna tenha sido maior nos animais produzidos a pasto. O sistema extensivo, predominantemente usado por criadores da raça Blanca Serrana Andaluza na Espanha, permite obter carcaças com características similares às dos animais criados em confinamento e, em virtude da significativa redução dos custos com alimentação, obtida com os animais exclusivamente a pasto, pressupõe-se que esse sistema seja mais economicamente viável.The objective of this study was to evaluate the influence of gender and production system on the carcass characteristics of Blanca Serrana Andaluza goats. Thirty-one animals were used, 12 males and 19 females, distributed in intensive (15 animals) and extensive (16 animals) production systems. No difference was observed in performance, carcass weight and body score between the gender or production system but the hot and cold carcass yields were greater for the animals finished in a feedlot. The carcass measurements did not differ, except for internal carcass length, which was longer for the animals under the intensive system. The percentage of non-constituent carcass components showed little variation for gender or the different rearing systems studied. The greatest proportions of perirenal fat were found in females and in the animals produced in feedlot. Little variation was observed for the shoulder, neck and breasts cuts, but the percentage of leg was greater in the animals produced in pasture. The extensive system, commonly used by Blanca Serrana Andaluza breeders in Spain, resulted in carcasses with characteristics similar to the animals reared in feedlot, and because of the substantial reduction in feeding costs obtained with animals exclusively on pasture, it is assumed to be the most economically viable system

Author Correction: The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers (Scientific Reports, (2019), 9, 1, (11486), 10.1038/s41598-019-47636-0)

Correction to: Scientific Reports https ://doi.org/10.1038/s4159 8-019-47636 -0, published online 07 August 2019 This Article contains errors. The Acknowledgements section in this Article is incomplete, the funding source LISBOA-01-0145-FEDER-016647 is omitted, “This work was supported by Animal Breeding Consulting S.L., Córdoba, Spain. This work was partially funded by the Veterinary Genetics Laboratory, University of California, Davis, VELOGEN S.L., Madrid, Spain and by Grupo de Referencia A19-17R LAGENBIO from Gobierno de Aragon/Fondo Social Europeo. C.G. was supported by Fundação Nacional para a Ciência e a Tecnologia (FCT), Portugal, Investigador FCT Grant IF/00, 866/2014, and Project grant PTDC/CVTLIV/2827/2014 co-funded by COMPETE 2020 POCI-01-0145-FEDER-016647. The authors thank the collaboration of breeders, breed associations and “Red Iberoamericana Sobre la Conservacion de la Biodiversidad de Animales Domesticos Locales para el Desarollo Rural Sostenible (Red CONBIAND)” for the sharing of biological samples. Members of the CYTED XII-H and CONBIAND networks are thanked for valuable cooperation over the years. Authors thank Juan Antonio Pereira (FCV-UAGRM, Bolivia) and Olivier Hanotte for their support with sampling Criollo Yacumeño and Eastern Shorthorn Zebu respectively.” should read: “This work was supported by Animal Breeding Consulting S.L., Córdoba, Spain. This work was partially funded by the Veterinary Genetics Laboratory, University of California, Davis, VELOGEN S.L., Madrid, Spain and by Grupo de Referencia A19-17R LAGENBIO from Gobierno de Aragon/Fondo Social Europeo. C.G. was supported by Fundação Nacional para a Ciência e a Tecnologia (FCT), Portugal, Investigador FCT Grant IF/00, 866/2014, Project grant PTDC/CVTLIV/2827/2014 co-funded by COMPETE 2020 POCI-01-0145-FEDER-016647 and LISBOA-01-0145-FEDER-016647. The authors thank the collaboration of breeders, breed associations and “Red Iberoamericana Sobre la Conservacion de la Biodiversidad de Animales Domesticos Locales para el Desarollo Rural Sostenible (Red CONBIAND)” for the sharing of biological samples. Members of the CYTED XII-H and CONBIAND networks are thanked for valuable cooperation over the years. Authors thank Juan Antonio Pereira (FCV-UAGRM, Bolivia) and Olivier Hanotte for their support with sampling Criollo Yacumeño and Eastern Shorthorn Zebu, respectively.” In addition, a Data Availability section is not included in the article – it should appear as below: “Data availability STR data used in our analysis is available in the Dryad repository: https :; doi.org/10.5061/dryad .5dv41 ns43”

The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received infuences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds difer considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African infuence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confrm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development

COVID-19 in hospitalized HIV-positive and HIV-negative patients : A matched study

CatedresObjectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10 922 patients in active-follow-up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non-PWH of the same age and sex randomly selected from COVID-19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID-19. The main outcome was all-cause in-hospital mortality. Results: Forty-five PWH with PCR-confirmed COVID-19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age/sex-matched controls were selected from the COVID-19@Spain cohort. The median age in both groups was 53 (Q1-Q3, 46-56) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV-RNA < 50 copies/mL, and the median (Q1-Q3) CD4 count was 595 (349-798) cells/μL. No statistically significant differences were found between PWH and non-PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non-PWH, respectively (P = 0.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non-PWH (P = 0.800). Conclusions: Our findings suggest that well-controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID-19 hospitalization