13 research outputs found
Bir devlet hastanesinde çalışan hemşirelerde tükenmişlik
Objective: This research were conducted for the purpose of examining nurses’ burnout levels who work in a government hospital according to some variables.Material and Method: 320 nurses constituted universe of research, all nurses were selected by disproportional group sample method constituted sample of research. The data were collected by using “Personal Information Form”, and “Burnout Measure”. The data gathered were analyzed in the program of SPSS. Findings: It was occurred nurses scored average 3.46±0.68 from Burnout Measure. On the other hand nurses have experienced most physical exhaustion (3.78±0.85) and it is followed by mental exhaustion (3.66±0.54), emotional exhaustion (2.93±1.03) (potential points distribution of measure and elements between 1-7). Nurses were separated among burnout groups according to continuous points in Burnout Measure. In grouping process, nurses who have between 1-3 points were assigned to burnout group-1; 3-4 points to group-2; 4-5 points to group-3; 5-7 points to group-4. It was determined that the 51.9% of nurses had in group 2, 27.8% of them had in group 1, 19.4% of them had in group 3, and 0.9% of nurses had in group 3. It was found characteristics of nurses gender, age, professional and experiences in their unit overcame with statistical relevancies; the variables like marital status, professional education, unit of working didn’t have weight with burnout level.Conclusion: Nurses within the scope of this research are experiencing burnout. Therefore, actions to prevent and to develop strategies for dealing to burnout of nurses must be planned and implemented in both organizational and individual basis.Amaç: Bu araştırma, bir devlet hastanesinde çalışan hemşirelerin tükenmişlik düzeylerini bazı değişkenler açısından incelemek amacı ile yapıldı. Gereç ve Yöntem: Araştırmanın evrenini, bir devlet hastanesinde çalışan 320 hemşire, örneklemini ise oransız küme örnekleme yöntemi ile seçilen tüm hemşireler oluşturdu. Veriler, "Kişisel Bilgi Formu" ve "Tükenmişlik Ölçeği" kullanılarak toplandı. Elde edilen veriler SPSS programında analiz edildi.Bulgular: Hemşirelerin Tükenmişlik Ölçeğinden aldıkları puanların ortalamasının 3.46±0.68 olduğu saptandı. Öte yandan hemşirelerin en fazla fiziksel tükenme (3.78±0.85) yaşadıkları, bunu sırası ile zihinsel (3.66±0.54) ve duygusal (2.93±1.03) tükenmenin izlediği saptandı (ölçeğin ve bileşenlerinin puan sınırı 1-7 arasındadır). Hemşireler, Tükenmişlik Ölçeğinden aldıkları sürekli puanlara göre, tükenme grupları içinde sınıflandırıldı. Bu sınıflandırma sürecinde, 1-3 arasında puan alan hemşireler tükenme grubu 1; 3-4 arası grup 2; 4-5 arası grup 3; 5-7 arası grup 4'e atandı. Hemşirelerin %51.9'unun grup 2'de, %27.8'inin grup 1'de, %19.4'ünün grup 3'te, %0.9'unun grup 4'te bulunduğu belirlendi. Hemşirelerin cinsiyet, yaş, mesleki ve çalıştığı birimdeki deneyim süresi özelliklerinin tükenmişlik düzeylerini istatistiksel anlamlılıklarla etkilediği; medeni durum, mesleki eğitim, çalıştığı birim değişkenlerinin tükenmişlik düzeyi üzerinde etkisi olmadığı saptandı.Sonuç: Araştırma kapsamındaki hemşireler tükenmişlik yaşamaktadır. Bu nedenle hem örgütsel hem de bireysel zeminde, hemşirelerin tükenmişliklerini önleme ve başa çıkma stratejileri geliştirmeye yönelik eylemler planlanmalı ve uygulanmalıdır
BNT162b2 COVID-19 vaccination elicited protective robust immune responses in pediatric patients with inborn errors of metabolism
IntroductionSARS-CoV-2 infection can lead to a life-threatening acute metabolic decompensation in children with inborn errors of metabolism (IEM), so vaccination is mandatory. However, IEMs can also impair innate or adaptive immunity, and the impact of these immune system alterations on immunogenicity and vaccine efficacy is still unknown. Here, we investigated humoral immune responses to the BNT162b2 mRNA COVID-19 vaccine and clinical outcomes in pediatric IEM patients.MethodsFifteen patients between 12-18 years of age with a confirmed diagnosis of IEM, and received BNT162b2 were enrolled to the study. Patients with an anti-SARS-CoV-2 IgG concentration >50 AU/mL before vaccination were defined as “COVID-19 recovered” whereas patients with undetectable anti-SARS-CoV-2 IgG concentration were defined as “COVID-19 naïve”. Anti-SARS-CoV-2 Immunoglobulin G (IgG) and SARS-CoV-2 neutralizing antibody (nAb) titers were measured to assess humoral immune response.ResultsAnti-SARS-CoV-2 IgG titers and nAb IH% increased significantly after the first dose. The increase in antibody titers after first and second vaccination remained significant in COVID-19 naïve patients. Complete anti-SARS-CoV-2 IgG seropositivity and nAb IH% positivity was observed in all patients after the second dose. Vaccination appears to be clinically effective in IEM patients, as none of the patients had COVID-19 infection within six months of the last vaccination.DiscussionHumoral immune response after two doses of BNT162b2 in pediatric IEM patients was adequate and the immune response was not different from that of healthy individuals