ChemTextMiner: An open source tool kit for mining medical literature abstracts

Text mining involves recognizing patterns from a wealth of information hidden latent in unstructured text and deducing explicit relationships among data entities by using data mining tools. Text mining of Biomedical literature is essential for building biological network connecting genes, proteins, drugs, therapeutic categories, side effects etc. related to diseases of interest. We present an approach for textmining biomedical literature mostly in terms of not so obvious hidden relationships and build biological network applied for the textmining of important human diseases like MTB, Malaria, Alzheimer and Diabetes. The methods, tools and data used for building biological networks using a distributed computing environment previously used for ChemXtreme[1] and ChemStar[2] applications are also described

MHRD’S INITIATIVE IIC CONTRIBUTION TOWARDS INNOVATION IN HIGHER EDUCATIONAL INSTITUTIONS DURING COVID 19

Innovation is the word which means new idea, creative thought, and practical implementation of invention. The MHRD initiative IIC is helpful for the students to learn entrepreneurship skills in their initial years of graduation and nurture them till completion of their qualification. The innovation cell of higher educational institutions will enhance the skills, aptitude of the students and prepare them for future endeavors. The main motive of MIC Innovation Cell is to inspire, persuade and cherish young and talented students to work with innovative thoughts and convert their ideas into prototypes and cherish their work. The e-sessions by the IIC-Institutes will overcome the need for physical innovation cell activities which is impossible in current situation due to COVID-19 pandemic. The quarter 3 and 4 have been merged into one period because of ongoing pandemic i.e., one complete semester and all IIC institutes have to report accordingly for the scores and star ratings. The e-sessions by IIC institutes have been successful and gathered appreciation from students and faculty members. There is a growing awareness that entrepreneurial outlook, which combines inventiveness, a sense of initiative, predicament solving, vagueness tolerance and financial and technological knowledge in formal education for benefit of individuals and society. The MHRD initiative of IIC will enable the foundation of robust modernization and Start up ecosystem across all HEIs

e-RUPI: A Purpose Specific Digital Voucher

e-RUPI is an advanced online resolution that has been launched by the National Payments Corporation of India (NPCI) in collaboration with the Department of Financial Services, Ministry of Health and Family Welfare, National Health Authority, and partner banks. It is just like a prepaid voucher that can be used by users to redeem an amount without a card, online payment application, or without accessing internet banking services. The present learning has explored the existing literature and aimed to discuss the merits and demerits of this emerging prepaid voucher, in the period of the COVID-19 pandemic. It has been found that the e-RUPI initiative of the Modi government will be fruitful for the beneficiaries as they will receive a direct benefit. It will be reliable and secure for both companies and customers. It suffers from ICT-related risks such as cyber fraud, hacking, lack of efficiency, and attitude of people towards adoption of this new resolution

A Study on Police Accountability and Custodial Violence in India

The present study aims to critically analyse the cases of custodial violence in the nation and also crucially examine the reasons of custodial deaths in India. The study attempted to enrich the existing literature on “A Study on police accountability and custodial violence in India”. In the study, the custodial violence has been divided into three categories namely physical, sexual and psychological. Various reasons have been encountered for the custodial deaths such as suicide, death due to treatment in the hospital, injuries sustained prior to custody, physical assault by police, while escaping from custody, road accidents connected with the journey etc. The study gives various recommendations to improve the police administration and foster the need for reforms in the working of police officials

FORENSIC ACCOUNTING: A WAY TO FIGHT, DETER AND DETECT FRAUD

Forensic Accounting is one of the emerging fields for accountancy professionals. Forensic Accounting is the function of bookkeeping, auditing and analytical expertise to combat the financial and white-collar crimes. The scope of forensic accounting has expanded due to cases of corporate scams and financial frauds. Forensic Accounting is the dynamic and strategic tool which helps in combating the corruption, financial crimes and frauds through the application of forensic auditing techniques. There is a huge demand for forensic auditors in the field of insurance, banks, police armed forces and government departments. This paper shows the application of information technology and cyber forensics to curb the malfunctioning done by corporate. In this paper role of the forensic auditor has been explained and the various techniques employed by forensic auditors have also been discussed. The latest cases in the field of forensic accounting have also been included in this paper. Forensic auditors can help the economy to grow and protect the interest of various stakeholders

Urachal Xanthogranuloma: A Rare but Important Case Presenting as a Urachal Mass

BACKGROUND: A urachal mass is a relatively rare presentation to the urologists\u27 practice, often requiring radical surgical excision for a definitive diagnosis. Xanthogranulomatous inflammation of the urachus is an extremely rare entity with few cases reported worldwide, and to the best of our knowledge, no cases reported in the western world. CASE PRESENTATION: In this case, a 55-year-old male patient presented with bothersome lower urinary tract symptoms and computed tomography findings demonstrating a urachal mass that was worrisome for urachal carcinoma. Following surgical intervention, histopathology revealed urachal xanthogranuloma. Post-operatively, the patient recovered well, and eventually, he had symptomatic and radiologic improvement. CONCLUSION: This case brings awareness to a rare presentation of a urachal mass-urachal xanthogranuloma. While operative intervention was both diagnostic and therapeutic, we highlight the challenge in differentiating between benign and malignant processes for urachal masses. Herein, we show the importance of including urachal xanthogranuloma in the differential diagnosis of a urachal mass to prevent further morbidity associated with the treatment of this disease

Ureteroscopy Under Conscious Sedation: A Proof-of-Concept Study

INTRODUCTION: Ureteroscopy (URS) is commonly performed under general anesthesia (GA) to maximize patient tolerability and minimize surgical complications; however, given the improvements in endoscopic technology and risks associated with GA, alternate forms of anesthesia have been postulated. We aimed to evaluate the outcomes of URS under conscious sedation. METHODS: We completed a retrospective cohort study from November 2019 to June 2020 at a tertiary-level hospital. All URSs that were performed under urologist-directed conscious sedation were included. Our primary outcome was the ability to complete URS, defined as success rate. Secondary outcomes included: stone-free rate, intraoperative complication rate, hospital admission rate, and sedation requirement. Univariate- and multivariate-adjusted logistic regression analyses were employed. RESULTS: Ninety-nine URSs were included. Most (73/99, 73.7%) were performed for urolithiasis. The overall success rate was 83.8% (83/99), with 81.0% (34/42) intra-renal and 70.0% (16/23) proximal ureter success rates. The stone-free rate was 80.8% (59/73). No intraoperative complications nor hospital admissions were reported. The mean amount of sedation required was 3 mg (interquartile range [IQR] 2-4] of midazolam and 100 μg (100-150) of fentanyl. On multivariate analysis, midazolam was significantly associated with increased success (odds ratio 2.496, 95% confidence interval 1.057-5.892, p=0.037). CONCLUSIONS: We have shown that proximal and intrarenal URS under conscious sedation is safe and effective. We were limited by our lack of followup, small sample size, selection bias to chose healthy patients, and lack of patient tolerability data. Patients and healthcare systems may benefit from implementing this innovation more broadly

Impact of the Naz Foundation judgment on the gay, bisexual and transgender people in Delhi: An empirical investigation

This report, prepared by the Centre for Health Law, Ethics and Technology (CHLET) at Jindal Global Law School, aims to determine and analyse the impact of the landmark judgment of July 2, 2009 by the Delhi High Court on the lives of sexual minorities in Delhi. The Court's judgment was in response to a petition challenging the constitutional validity of Section 377 of the Indian Penal Code (IPC), which criminalised consensual sexual activities between homosexual adults conducted in private. In the judgment, the Honourable Chief Justice Ajit Prakash Shah and Justice S. Muralidhar held that Section 377 infringed upon fundamental rights under Articles 14, 15, and 21 of the Constitution of India, and declared the section to be unconstitutional to the extent that it criminalised private consensual sexual activity between adults. The research conducted for this study consists mostly of personal interviews with members of the LGBT community. Researchers interacted with individuals belonging to different sexual minorities who described their lives before and after July 2, 2009. The findings of the interviews have been compiled along with similar studies conducted in other parts of the world: South Africa, the USA, Canada and Australia. These studies have been compiled and correlated in order to paint a global picture, showing that decriminalisation consistently leads to a rise in the level of social acceptance and, more importantly, self-acceptance of sexual minorities. This impact assessment is the first of its kind in India and, apart from providing valuable first-hand accounts of LGBT life pre and post-decriminalisation of homosexuality, it aims to (i) bring attention to other issues (such as strategies for the promotion of familial acceptance of LGBTs) that still need to be addressed; and (ii) emphasize the role of other factors such as movies and the Indian media that, through their activities and support for the LGBT community, have had an important positive impact on societal acceptance

Management of Fibromyalgia: An Update

Fibromyalgia, a chronic pain condition marked by abnormal pain processing, impacts a significant part of the population, leading to reduced quality of life and function. Hallmark symptoms include widespread persistent pain, sleep disturbances, fatigue, cognitive dysfunction, and mood changes. Through this updated review, we aim to contribute to the evolving understanding and management of fibromyalgia, offering insights into the diverse tools available to improve the lives of those affected by this challenging condition. Management begins with educating patients to ultimately relieve them of unnecessary testing and provide reassurance. Treatment emphasizes a comprehensive approach, combining nonpharmacological interventions such as aforementioned education, exercise, and psychotherapy, alongside pharmacologic management-namely duloxetine, milnacipran, pregabalin, and amitriptyline-which have consistent benefits for a range of symptoms across the spectrum of fibromyalgia. Notably, drugs like nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are generally not recommended due to limited efficacy and associated risks. Lastly, a variety of other medications have shown promise, including NMDA-receptor antagonists, naltrexone, and cannabinoids; however, they should be used with caution due to a small amount of evidence and potential for adverse effects