Determination of Co-infection in Diseased Seven khramulya (Capoeta capoeta)

This study was conducted identify the cause of mortality in diseased Seven khramulya (Capoeta capoeta) and to determine the damage to the fish tissue caused by the agents identified. While hemorrhage on the fins and abdominal region of diseased fish, necrosis in gills, darkening color and loss of scales were externally determined, the presence of bloody and smelling liquid in the abdominal cavity, necrosis of visceral organs, splenomegaly, hyperemia and hemorrhage in the visceral organs were internally observed. As a result of the parasitological examination, Grrodactrlus sp. were found on the gills of the diseased fish. and Trichodina sp. were found on their skin. Bacteriologically. isolated bacteria were identified as Aeromonas hydrophila, Vibrio fluvialis, Staphylococcus warneri and S capitis. Histopathologically, thickening of epicardium in heart tissue, myopathy, periglomerular and tubular edema melanomacrophage and hemosiderin foci, the infiltration of inflammatory cells in the kidney, hyperemia, infiltration of inflammatory cells in the liver were observed. A. hydrophila, V. fluvialis, S warneri, and S capitis were first isolated and identified as disease agents from the co-infection in diseased Seven khyramulya, and furthermore, pathological changes in tissues caused by these pathogenic bacteria were investigated in detail

A comparative histological study on early thyroid gland development in Acipenser stellatus and A. gueldenstaedtii larvae in hatchery

The thyroid is an endocrine gland, with an important role in fish growth, development and adaptation of larvae. The aim of this study was to describe the development of the thyroid gland and to determine the initial functional activity of thyroid gland and hormones in Acipenser gueldenstaedtii and A. stellatus larvae using immunohistochemistry. For this aim, fertilized eggs of two species were reared in a hatchery and larval samples were collected daily for 20 days post hatching (dph). For immunostaining, rabbit polyclonal primary antibodies for thyroglobulin and mouse monoclonal antibodies for thyroid transcription factor-1 (TTF-1) were used. In histological analyses, it was observed that the first development of the thyroid gland in stellate sturgeon larvae occurs on the 3-4 dph and on the 4-5 dph in Russian sturgeon larvae in the ventral pharyngeal region of the fish. In the immunostaining analyses of 12-day-old stellate larvae and 19-day-old Russian sturgeon larvae, the thyroid follicles showed dispersion in great numbers around the aorta, and also it was observed that they were stained positively with antithyroglobulin staining, but the same sections gave negative results with TTF-1 staining. Also melanomacrophage centres, which are generally found in the haemopoietic tissues in some cases, were first observed around the thyroid follicles of sturgeon larvae. The results of this study revealed a similarity in the early thyroid gland development between two sturgeon species but using immunostaining methods, it was described that A. stellatus shows a faster functional development and earlier hormone production than A. gueldenstaedtii

Hasta Siraz Balıklarında (Capoeta capoeta )Görülen Ko-Enfeksiyonun Tanımlanması

This study was conducted identify the cause of mortality in diseased Seven khramulya (Capoeta capoeta) and to determine the damage to the fish tissue caused by the agents identified. While hemorrhage on the fins and abdominal region of diseased fish, necrosis in gills, darkening color and loss of scales were externally determined, the presence of bloody and smelling liquid in the abdominal cavity, necrosis of visceral organs, splenomegaly, hyperemia and hemorrhage in the visceral organs were internally observed. As a result of the parasitological examination, Grrodactrlus sp. were found on the gills of the diseased fish. and Trichodina sp. were found on their skin. Bacteriologically. isolated bacteria were identified as Aeromonas hydrophila, Vibrio fluvialis, Staphylococcus warneri and S capitis. Histopathologically, thickening of epicardium in heart tissue, myopathy, periglomerular and tubular edema melanomacrophage and hemosiderin foci, the infiltration of inflammatory cells in the kidney, hyperemia, infiltration of inflammatory cells in the liver were observed. A. hydrophila, V. fluvialis, S warneri, and S capitis were first isolated and identified as disease agents from the co-infection in diseased Seven khyramulya, and furthermore, pathological changes in tissues caused by these pathogenic bacteria were investigated in detail

Histopathology Characteristics of two Different Benign Tumours in Capoeta capoeta

The aim of the present study was to determine the morphologic and histopathologic characteristics of tumors observed in samples from moribundCapoeta capoeta. For this purpose, ten fish, captured from the Fırat River located in southeastern Anatolia of Turkey, were examined for gross malformations and histopathological morphology. Externally, two different morphological types of tumours were detected in the anus region and on the ventral part of the operculum of one of the examined fish. In this study, tumours in a moribund fish were identified as benign because they were well differentiated, non‐infiltrative and non‐metastatic. In the histological examination, the external growth located in the ventral region of the operculum was characteristic of a papilloma showing exophytic inverted development. This is our first report on both melanomacrophage and green fibrils in the papilloma. The other observed pathological growth, covered with hemorrhagic skin and located near the anus, was characteristic of a benign tumour (subcutaneous lipoma) which constituted typical adipocytes. Thus, our study detected two different types of benign tumours inCapoeta capoeta, and it is the first time being reported in a cyprinid specie

Effects of Ibuprofen on Orthotopic Glioma Model in Rats

Objective: To determine the effects of ibuprofen (Ibp) on the vessel proliferation and necrosis in a rat glioma model

Some reproductive aspects of female bullet tuna, Auxis rochei (Risso), from the Turkish Mediterranean coasts

The study aims to investigate some reproductive properties of bullet tuna (Auxis rochei) in Turkish waters. A total of 216 bullet tunas, 110 males (50.93%) and 106 females (49.07%), from the Turkish Mediterranean coasts were sampled monthly between December 2008 and December 2009. The sex ratio was 1:1.04. A total of 106 ovaries were obtained from the females, and these ovaries were histologically examined to determine the reproductive conditions and developmental stages of oocytes. The gonado-somatic index (GSI) values calculated for females indicated that spawning generally occurred between May and September. The most intensive spawning period was observed between June and August. A total of 40 females collected between May and September were sexually mature

Ovarian teratoma in a dog

A 3-year-old female dog was referred to the clinics of Istanbul University with the complaint of abdominal distention. On the basis of the clinical findings and ultrasonography, a mass was detected in the left ovary. An ovariohysterectomy was performed. Grossly, the mass, with dimensions of 15 x 11 x 8 cm, weighed 1.2 kg and contained hairs, cysts, fat, bone, and cartilage on the cut surface. Histology revealed the occurrence of well-differentiated components of all 3 germ layers and the mass was diagnosed as a benign mature cystic teratoma

Combination hyperbaric oxygen and temozolomide therapy in c6 rat glioma model

PURPOSE: Temozolomide (TMZ) has anti-tumor activity in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are limited because of the hypoxic tumor microenvironment. We examined the combined effects of TMZ-HBO in a rat glioma model

Adult Langerhans cell histiocytosis and sclerosing cholangitis: a case report and review of the literature

Sclerosing cholangitis is a rare complication of Langerhans cell histiocytosis in children which can result in liver failure. This combination is even rarer in adults