1,587 research outputs found
Analisis Kepuasan Mahasiswa FKIP Atas Kualitas Layanan Akademik Di Pusat Pelayanan Terpadu Universitas PGRI Palembang
ABSTRAK Penelitian ini bertujuan untuk (1) mengetahui apakah Kepuasan Mahasiswa FKIP atas Kualitas Layanan Akademik di Pusat Pelayanan Mahasiswa Universitas PGRI Palembang telah terpenuhi dan sesuai harapan mahasiswa, (2) untuk mengetahui instrument kualitas layanan (tangibles, reliability, responsiveness, assurance, dan empathy) mana yang memberikan kepuasan kepada mahasiswa FKIP Universitas PGRI Palembang tahun 2019-2020. Metode yang digunakan dalam penelitian ini adalah metode deskriptif untuk menggambarkan hubungan antar variabel melalui pengujian hipotesis. Penelitian ini menggunakan kuesioner sebagai alat pengumpulan data yang didistribusikan kepada 98 responden dari mahasiswa FKIP yang terpilih sebagai responden pada tahun akademik 2019-2020, dimana ada 7 item pertanyaanuntuk variable kualitas layanan dan 8 item pertanyaan untuk variable kepuasan mahasiswa. Berdasarkan hasil penelitian yang dilakukan, terdapat pengaruh yang signifikan secara simultan antara variabel kualitas layanan akademik (X) terhadap variabel kepuasan mahasiswa (Y). Ini dibuktikan dengan memperoleh dengan perolehan perhitungan lebih besar dari t tabel (5.207> 1,660) dan koefisien 0,000 dan nilainya positif. Kata kunci: Kepuasan Mahsiswa, Kulaitas Layanan Akdemik ABSTRACT This study aims to (1) find out whether FKIP Student Satisfaction on the Quality of Academic Services at the Student Service Center of PGRI Palembang University has been fulfilled and according to student expectations, (2) to determine service quality instruments (tangibles, reliability, responsiveness, assurance, and empathy) which one gives satisfaction to FKIP students at PGRI Palembang University in 2019-2020. The method used in this study is a descriptive method to describe the relationship between variables through hypothesis testing. This study used a questionnaire as a data collection tool which was distributed to 98 respondents from FKIP students who were selected as respondents in the 2019-2020 academic year, where there were 7 question items for the service quality variable and 8 question items for the student satisfaction variable. Based on the results of the research conducted, there is a simultaneous significant effect between the academic service quality variable (X) on the student satisfaction variable (Y). This is evidenced by obtaining a calculation greater than t table (5.207 > 1.660) and a coefficient of 0.000 and the value is positive. Keywords: Student Satisfaction, Academic Service Qualit
Hubungan Lingkungan dan Disiplin Kerja Terhadap Kinerja Guru dalam Proses Pembelajaran
This study aims to determine the relationship between the work environment and work discipline, both partially and on the performance of teachers at SMK PGRI 1 Palembang. The type of research used in this research is descriptive analysis with a quantitative approach to describe the relationship between variables through hypothesis testing. This study used a questionnaire as a data collection tool which was distributed to 42 respondents from SMK PGRI 1 Palembang. Based on the results of the research conducted, there is a simultaneous significant relationship between the Work Environment and Work Discipline variables on the Teacher Performance variable in the Learning Process. This is evidenced by obtaining Fcount 6.622 which is greater than Ftable 2.850. In addition, it is known that partially the Work Environment (X1) has no relationship with Teacher Performance (Y). This is evidenced by the acquisition of tcount 1.078 < ttable 2.023, and coefficient 0.288. Meanwhile, Work Discipline (X2) has a positive and significant relationship to Teacher Performance (Y). This is evidenced by the acquisition of tcount which is greater than ttable (2.782 > 2.023) and the coefficient is 0.008 and the value is positive.
Keywords: work environment, work discipline and teacher performanc
Mechanical properties of three-phase polyamide 6 nanocomposites
This work focus on the mechanical properties of three-phase nanocomposites using multiscale reinforcements. The influence of the nano-fillers content, as well as the temperature were studied. Polyamide-6 reinforced with short glass fibre 30 wt.% and with an addition of nanoclay (montmorillonite) and/or nanosilica (SiO2) were tested in order to characterise their tensile properties at room temperature and at 65oC just above the polyamide 6 glass transition temperature. SEM analysis were conducted on the fracture surface of the tensile bars. SEM investigations showed the importance of the interaction matrix/filler for the material behaviour. Our study also shows that the increase of OMMT percentage in polyamide-6/glass fibre composite made the material more brittle and had a negative effect on the tensile properties. Further, for the silica-based nanocomposites, an optimum was found for a nanofillers content of 1wt.%
Maximum likelihood estimation for nonembeddable Markov chains when the cycle length is shorter than the data observation interval
Time-homogeneous Markov chains are often used as disease progression models
in studies of cost-effectiveness and optimal decision-making. Maximum
likelihood estimation of these models can be challenging when data are
collected at a time interval longer than the model's transition cycle length.
For example, it may be necessary to estimate a monthly transition model from
data collected annually. The likelihood for a time-homogeneous Markov chain
with transition matrix and data observed at intervals of
cycles is a function of The maximum likelihood estimate of
is easily obtained from the data. The th root of this
estimate would then be a maximum likelihood estimate for However,
the th root of is not necessarily a valid transition matrix.
Maximum likelihood estimation of is a constrained optimization
problem when a valid root is unavailable. The optimization problem is not
convex. Local convergence is explored in several case studies through graphical
representations of a grid search. The example cases use disease progression
data from the literature as well as synthetic data. The global maximum
likelihood estimate is increasingly difficult to locate as the number of cycles
or the number of states increases. What seems like a straightforward estimation
problem can be challenging even for relatively simple models. Researchers
should consider alternatives to likelihood maximization or alternative models.Comment: 33 pages, 12 main figures + 6 supporting figure
Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease
The etiology of Alzheimer’s disease (AD) remains a great challenge for neurological research.
Extensive investigations for almost one hundred years have led to profound insights of the
pathological and molecular mechanisms that affect the AD brain, and there are several
hypotheses about what causes the characteristic AD related dementia. The focus has fallen
increasingly on the deposition of ß-amyloid (Aß) in the cortex and it is believed, that the
generation and deposition of Aß is the leading cause of the disruptions observed in the AD
brain. Aß has been shown to provoke neuron death, decreased synaptic plasticity, aberrant
sprouting of growing axons, chronic inflammation and hyper-phosphorylation of tau.
In recent years, research on adult neurogenesis in the mammalian brain has led to surprising
findings: new neurons are added daily to specific regions of the brain and growing evidence
suggests that these new neurons play a critical role for learning and memory, mood and, to a
limited amount, repair of damaged cortical areas. All of these functionalities of neurogenesis
are affected in AD patients and the question must be raised, if in the AD brain, neurogenesis
is directly disturbed. Defects in neural stem cell biology might significantly contribute to AD
dementia and the examination of the relationship of AD lesions and neural stem cell biology
might provide new insights for the understanding and treatment of AD.
Only recently has it become possible to investigate neural stem cell biology in the AD brain.
This is partly because only recent findings revealed the function of adult neural stem cells, but
also because animal models for AD have only been available for few years. However, most
AD mouse models, which are genetically engineered for Aß deposition, do not develop
significant amyloid plaques until past their median lifespan. This limits their availability and
the specificity to Aß is reduced due to accompanying age effects.
In a first study of this thesis, age related changes of neurogenesis were investigated by
monitoring the progressive stages of hippocampal neurogenesis: proliferation, survival and
differentiation, in four different age groups of wild type C57BL/6J mice. Net-neurogenesis
was rapidly reduced in adult compared to young mice, but remained stable at a low level in
aged and senescent mice. This effect could be attributed mostly to an age related decline of
proliferation with a concomitant increase of survival rates in aged mice. These results suggest
that neurogenesis in aged mice remains as functional as in adult mice, although the plasticity
of the neurogenic system appears to be reduced compared to young mice. The finding that a
reduced caloric diet, a treatment known to reduce age related defects, did not have an effect
on neurogenesis confirmed the finding that neurogenesis is not impaired in aged mice
compared to adult mice.
In a second study neurogenesis was studied in APP23 mice, a transgenic AD mouse model
with progressive amyloid plaque load. Adult Aß pre-depositing and aged Aß high-depositing
mice were investigated. Surprisingly, aged APP23 mice showed an increased number of new
neurons in the hippocampus compared to age matching controls. For a closer investigation of
the interaction of neural stem cells and Aß, we crossed mice expressing GFP under a stem cell
specific promoter with a new AD mouse model with cortical plaque deposition in early
adulthood. Stem cells were reduced in numbers, strongly attracted to Aß and morphologically
altered. In addition, the population of more differentiated immature neurons appeared to be
morphologically unaffected by Aß. These findings show that Aß affects neural stem cell
biology concomitant with an up-regulation of neurogenesis.
Several reports claim that stem cells from the periphery are able to cross the blood brain
barrier and are able trans-differentiate to the neuronal lineage. It has also been shown, that the
number of cells immigrating from the periphery increases in AD mouse models. Thus, in a
third study we investigated if stem cells from the peripheral hematopoietic system could
participate in the repair or replacement of the damaged neuronal tissue. APP23 mice were
deprived of their immune system by gamma irradiation and later reconstituted with
genetically marked hematopoietic stem cells. We found a large number of these cells invading
the brains of aged APP23 mice, but cell fate analysis revealed that these cells matured to
macrophages or T-cells, but none differentiated towards the neuronal lineage. We conclude
that the hematopoietic system is involved in the immune response in the brain, but we found
no evidence that it is involved the in repair of the damaged network or in the alterations of
neural stem cell biology described above.
In conclusion, the results of the present thesis provide evidence of a defective behavior of
neural stem cells in the amyloidogenic brain, but also unveil the limitations in the function
and ability of neural stem cells in the aged brain
Pengaruh Motivasi Terhadap Kinerja Karyawan Pada UPT Divisi IT, Infokom dan Pusdikom Universitas PGRI Palembang
Rumusan masalah dalam penelitian ini adalah bagaimana pengaruh motivasi terhadap kinerja karyawan pada UPT Divisi IT, Infokom dan Pusdikom Universitas PGRI Palembang. Sedangkan tujuan penelitian ini untuk mengetahui apakah ada pengaruh motivasi terhadap kinerja karyawan pada UPT Divisi IT, Infokom dan Pusdikom Universitas PGRI Palembang. Teknik analisis yang digunakan dalam penelitian ini adalah regresi linier sederhana, analisis korelasi dan uji hipotesis t. Metode yang digunakan yaitu analisis kuantitatif. Hasil analisis yang diperoleh dengan menggunakan rumus regresi linier sederhana yaitu y = 7,02 + 0,88X. dengan analisis korelasi didapat nilai r = 0,63. ini berarti terdapat pengaruh yang kuat antara motivasi terhadap kinerja karyawan pada UPT Divisi IT, Infokom dan Pusdikom Universitas PGRI Palembang, yaitu 39,69%. Dan menolak hipotesis nol karena nilai t-hitung lebih besar dari t-tabel, yaitu 4,29 > 2,045. Semakin tinggi motivasi maka kinerja yang dihasilkan akan meningkat. Dari hasil analisis ini dapat diambil kesimpulan bahwa motivasi mempunyai pengaruh yang kuat terhadap kinerja karyawan dan sebaiknya pimpinan dapat menerapkan pola kerja yang efektif sebagai bentuk motivasi agar kinerja karyawan itu sendiri dapat meningkat dan pada akhirnya tujuan organisasi dapat tercapai. Kata Kunci : Motivasi dan Kinerj
Hydromorphic analysis of urban area transformation: the case study of the Matera city
The paper analyzes the urban context of Matera city, adopting an approach based on
the concept of watershed, interpreted in its dynamic meaning. This approach exceeds the
classical urban planning analysis by focusing on the interaction between the morphological
characteristics of the territory, the land uses and their human-made changes and the consequent
hydrological response and surface runoff. The morphological description combined with the
classic urban representation that looks at the types of intervention implemented (permeable,
impervious, green, land uses) drive into the understanding of the urban and territorial
transformation processes responses. Furthermore the urban evolution analysis for different time
period can provide a time-based interpretation of the transformations impacts providing useful
information for future planning of the entire area of Matera
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