Medium-Early Spring Wheat Cultivars Depending on The Level of Mineral Nutrition in The Northern Forest-Steppe of The Tyumen Region

This article analyzes the results by the yield and grain quality of two spring wheat cultivars Tyumenskaya Yubileynaya and Tyumenocka, depending on the level of mineral nutrition in the forest-steppe zone of the Tyumen region. The length of the vegetation period corresponded to the climatic conditions of the forest-steppe zone of the Tyumen region. In the reference variant and the variant with 4 tons of NPK per hectare, it was 90 days, and in the variants with 4 and 6 t/ha, it was 92 days. In the reference variant, the average yield of the Tyumenskaya Yubileynaya cultivar over the three years was 3.31 t/ha, and that of the Tyumenocka cultivar — 2.93 t/ha. The introduction of mineral fertilizers for the planned yield of 4 t/ha allowed obtaining the yield for the Tyumenskaya Yubileynaya cultivar equal to 4.14 t/ha, which was by 0.83 t/ha more than in the reference variant. The Tyumenocka cultivar yielded 3.83 t/ha, which was by 0.90 t/ha higher than in the reference variant. Further increasing the dosages of mineral fertilizers to 5 t/ha allowed obtaining 4.73 – 4.72 t/ha for both cultivars, which was by 0.27 – 0.28 t/ha lower than planned yield. The content of gluten in the grain of cultivar Tyumenskaya Yubileynaya in the reference variant was 27.2 %, of the Tyumenocka cultivar — 24.2 %. In the variant with 4 tons of NPK per hectare, an increase in the content of gluten by 9.6 – 10.4 %, respectively, was noted. According to the economic calculations, the most favorable for spring wheat cultivation in the Tyumen region is the level of mineral fertilization equal to 5 tons of NPK per hectare

Physicochemical Properties of Gray Forest Soils on the Eastern Outskirts of the Trans-Ural Plateau

Серые лесные почвы наиболее перспективны для расширения пахотного фонда Северного Зауралья. Разнообразие ландшафта, почвообразующих пород, влияние антропогенного фактора стали причинами варьирования их свойств в широком диапазоне. Целью исследования являлось изучение физико-химических свойств серых лесных почв и установление характера их изменчивости. Объект исследования – целинные серые лесные почвы (Luvic Retic Greyzemic Phaeozems). Было заложено 330 полнопрофильных разрезов, выполнено их морфологическое описание, отобраны по генетическим горизонтам почвенные образцы для лабораторных анализов. Результаты исследований показали, что серые лесные почвы восточной окраины Зауральского Плато в агрономическом отношении имеют сравнительно благоприятные физико-химические свойства. По мере снижения интенсивности оподзоливания сумма обменных оснований в гумусовых горизонтах возрастает от 17,2 в светло-серых до 25,3 ммоль(экв)/100 г в темно-серых почвах. Выявлена высокая степень варьирования значений гидролитической кислотности темно-серых лесных почв Северного Зауралья от 1,1 до 13,0 ммоль(экв)/100 г почвы (коэффициент вариации в гумусовом горизонте равен 43 %). В светло-серых и собственно серых лесных почвах гидролитическая кислотность характеризуется меньшими значениями – 4,6 и 5,2 ммоль(экв)/100 г почвы соответственно. Поглотительная способность серых лесных почв относительно высока, даже у подтипа светло-серых, где она варьирует в широком диапазоне – от 12,2 до 31,0 ммоль(экв)/100 г почвы. В темно-серых почвах Северного Зауралья емкость катионного обмена в гумусовом горизонте в среднем составляет 32,1 ммоль(экв)/100 г почвы, уменьшаясь с глубиной. Степень насыщенности основаниями гумусового горизонта в темно-серых лесных почвах достигает 79 % от емкости катионного обмена с варьированием значений от 67 до 95 %. Схожие физико-химические свойства светло-серых и собственно серых лесных почв позволяют объединить их в одну агропроизводственную группу для разработки единой системы земледелия, обеспечивающей расширенное воспроизводство плодородия. При сельскохозяйственном использовании темно-серых лесных почв необходимо учитывать очень высокую вариабельность их физико-химических свойствGray forest soils are the most promising for expanding the arable area in Northern Trans-Urals. The diversity of landscape and soil-forming rocks and human impact resulted in a wide range of their properties. The aim of the research is to examine the physicochemical properties of gray forest soils and determine the nature of their variability. The object of research is virgin gray forest soils (Luvic Retic Greyzemic Phaeozems). Three hundred and thirty full-profile sections were laid, their morphological description was provided, soil samples for laboratory analysis were selected according to genetic horizons. The results of the research show that gray forest soils on the eastern outskirts of the Trans-Ural Plateau have physical and chemical properties relatively favorable from an agronomic perspective. As the intensity of podzolization decreases, the total amount of exchangeable bases in humus horizons increases from 17.2 to 25.3 mmol (eq)/100 g in light gray and dark gray soils, respectively. A high degree of variation in the values of hydrolytic acidity of dark gray forest soils in Northern Trans-Urals, from 1.1 to 13.0 mmol (eq)/100 g of soil, was revealed (the variation coefficient in the humus horizon is 43 %). In light gray and gray forest soils, hydrolytic acidity is characterized by lower values: 4.6 and 5.2 mmol (eq)/100 g of soil, respectively. The absorption capacity of all gray forest soils is relatively high, even in the light gray subtype, where it varies in a wide range – from 12.2 to 31.0 mmol (eq)/100 g of soil. In dark gray soils of Northern Trans-Urals, the average cation exchange capacity is 32.1 mmol (eq)/100 g of soil, decreasing with depth. The degree of humus horizon saturation with bases in dark gray forest soils reaches 79 % of the cation exchange capacity varying from 67 to 95 %. Similar physical and chemical properties of light gray and gray forest soils make it possible to place them into one agricultural production group to develop a unified farming system that provides enhanced restoration of soil fertility. In the agricultural use of dark gray forest soils, it is necessary to take into account immensely high variability of their physicochemical propertie

Evaluation of phytotoxicity and cytotoxicity of industrial catalyst components (Fe, Cu, Ni, Rh and Pd): A case of lethal toxicity of a rhodium salt in terrestrial plants

Until recently, chemical derivatives of platinum group metals have not been in a systematic direct contact with living organisms. The situation has changed dramatically due to anthropogenic activity, which has led to significant redistribution of these metals in the biosphere. Millions of modern cars are equipped with automotive catalytic converters, which contain rhodium, palladium and platinum as active elements. Everyday usage of catalytic technologies promotes the propagation of catalyst components in the environment. Nevertheless, we still have not accumulated profound information on possible ecotoxic effects of these metal pollutants. In this study, we report a case of an extraordinarily rapid development of lethal toxicity of a rhodium (III) salt in the terrestrial plants Pisum sativum, Lupinus angustifolius and Cucumis sativus. The growth stage, at which the exposure occurred, had a crucial impact on the toxicity manifestation: at earlier stages, RhCl3 killed the plants within 24 h. In contrast, the salt was relatively low-toxic in human fibroblasts. We also address phytotoxicity of other common metal pollutants, such as palladium, iron, nickel and copper, together with their cytotoxicity. None of the tested compounds exhibited phytotoxic effects comparable with that of RhCl3. These results evidence the crucial deficiency in our knowledge on environmental dangers of newly widespread metal pollutants

Anchor system for installation of fishing gears on soft grounds

Mushroom anchors are proposed for positioning of vessels and fishing gears on soft grounds, as sands and silts. Designs of the anchors of original shape are presented. Their holding force is determined for certain navigational conditions, and the forces acting on a floating object are calculated for the cases of anchoring perpendicular and parallel to the water flow. Weight of the mushroom anchors necessary for anchoring of a floating object is calculated and scheme of the anchorage is presented for the depth 250 m. The mushroom anchors using for rescue operations in the Okhotsk Sea and for shrimp pot fishery in the Japan Sea is discussed, in particular the episode of positioning the vessel of deadweight 2433 t in conditions of 3-points roughness and the current velocity 2 knots at the sea surface and 4 knots at the sea bottom with using two stern and one bow mushroom anchors. Using of the compact mushroom anchor for shrimp pot fishery allows to reduce the traps moving along the bottom during their hauling. Possibly, the mushroom anchors could be used for other gears installation, as well, as stationary nets, crab traps, bottom longlines, etc

Bremsstrahlung emission during α\alpha-decay of 226Ra^{226}{\rm Ra}

We obtained the spectrum of probability of the bremsstrahlung emission accompanying the $\alpha$-decay of $^{226}{\rm Ra}$ (E$_{\alpha}$=4.8 MeV) by measuring the $\alpha$-$\gamma$ coincidences and using the model presented in our previous study on the $\alpha-$decay of $^{214}{\rm Po}$ (E$_{\alpha}$=7.7 MeV). We compare the experimental data with the quantum mechanical calculation and find a good agreement between theory and experiment. We discuss the differences between the photon spectra connected with the $\alpha$-decay of the $^{226}{\rm Ra}$ and $^{214}{\rm Po}$ nuclei. For the two mentioned nuclei we analyze the bremsstrahlung emission contributions from the tunneling and external regions of the nucleus barrier into the total spectrum, and we find the destructive interference between these contributions. We also find that the emission of photons during tunneling of the $\alpha$-particle gives an important contribution to the bremsstrahlung spectrum in the whole E$_{\gamma}$ energy range of the studied $^{226}$Ra nucleus

EPMA-World Congress 2015: Bonn, Germany. 3-5 September 2015

Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of IDO in a murine model of gingivitis: predictive and therapeutic potentials Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari A6 Specific diets for personalised treatment of diabetes type 2 Viktoriia V. Bati, Tamara V. Meleshko, Olga B. Levchuk, Nadiya V. Boyko A7 Towards personalized physiotherapeutic approach Joanna Bauer, Ewa Boerner, Halina Podbielska A8 Cells, animal, SHIME and in silico models for detection and verification of specific biomarkers of non-communicable chronic diseases Alojz Bomba, Viktor O. Petrov, Volodymyr G. Drobnych, Rostyslav V. Bubnov, Oksana M. Bykova, Nadiya V. Boyko A9 INTERACT-chronic care model: Self-treatment by patients with decision support e-Health solution Hans-Peter Brunner-La Rocca, Lutz Fleischhacker, Olga Golubnitschaja, Frank Heemskerk, Thomas Helms, Tiny Jaarsma, Judita Kinkorova, Jan Ramaekers, Peter Ruff, Ivana Schnur, Emilio Vanoli, Jose Verdu A10 PPPM in cardiovascular medicine in 2015 Hans-Peter Brunner-La Rocca A11 Magnetic resonance imaging of nanoparticles in mice, potential for theranostic and contrast media development – pilot results Rostyslav V. Bubnov, Sergiy A. Grabovetskyi, Olena M. Mykhalchenko, Natalia O. Tymoshok, Oleksandr B. Shcherbakov, Igor P. Semeniv, Mykola Y. Spivak A12 Ultrasound diagnosis for diabetic neuropathy - comparative study Rostyslav V. Bubnov, Tetyana V. Ostapenko A13 Ultrasound for stratification patients with diabetic foot ulcers for prevention and personalized treatment - pilot results Rostyslav V. Bubnov, Nazarii M. Kobyliak, Nadiya M. Zholobak, Mykola Ya. Spivak A14 Project ImaGenX – designing and executing a questionnaire on environment and lifestyle risk of breast cancer John Paul Cauchi A15 Genomics – a new structural brand of predictive, preventive and personalized medicine or the new driver as well? Dmitrii Cherepakhin, Marina Bakay, Artem Borovikov, Sergey Suchkov A16 Survey of questionnaires for evaluation of the quality of life in various medical fields Barbara Cieślik, Agnieszka Migasiewicz, Maria-Luiza Podbielska, Markus Pelleter, Agnieszka Giemza, Halina Podbielska A17 Personalized molecular treatment for muscular dystrophies Sebahattin Cirak A18 Secondary mutations in circulating tumour DNA for acquired drug resistance in patients with advanced ALK + NSCLC Marzia Del Re, Paola Bordi, Valentina Citi, Marta Palombi, Carmine Pinto, Marcello Tiseo, Romano Danesi A19 Recombinant species-specific FcεRI alpha proteins for diagnosis of IgE-mediated allergies in dogs, cats and horses Lukas Einhorn, Judit Fazekas, Martina Muhr, Alexandra Schoos, Lucia Panakova, Ina Herrmann, Krisztina Manzano-Szalai, Kumiko Oida, Edda Fiebiger, Josef Singer, Erika Jensen-Jarolim A20 Global methodology for developmental neurotoxicity testing in humans and animals early and chronically exposed to chemical contaminants Arpiné A. Elnar, Nadia Ouamara, Nadiya Boyko, Xavier Coumoul, Jean-Philippe Antignac, Bruno Le Bizec, Gauthier Eppe, Jenny Renaut, Torsten Bonn, Cédric Guignard, Margherita Ferrante, Maria Liusa Chiusano, Salvatore Cuzzocrea, Gerard O'Keeffe, John Cryan, Michelle Bisson, Amina Barakat, Ihsane Hmamouchi, Nasser Zawia, Anumantha Kanthasamy, Glen E. Kisby, Rui Alves, Oscar Villacañas Pérez, Kim Burgard, Peter Spencer, Norbert Bomba, Martin Haranta, Nina Zaitseva, Irina May, Stéphanie Grojean, Mathilde Body-Malapel, Florencia Harari, Raul Harari, Kristina Yeghiazaryan, Olga Golubnitschaja, Vittorio Calabrese, Christophe Nemos, Rachid Soulimani A21 Mental indicators at young people with attributes hypertension and pre-hypertension Maria E. Evsevyeva, Elena A. Mishenko, Zurida V. Kumukova, Evgeniy V. Chudnovsky, Tatyana A. Smirnova A22 On the approaches to the early diagnosis of stress-induced hypertension in young employees of State law enforcement agencies Maria E. Evsevyeva, Ludmila V. Ivanova, Michail V. Eremin, Maria V. Rostovtseva A23 Сentral aortic pressure and indexes of augmentation in young persons in view of risk factors Maria E. Evsevyeva, Michail V. Eremin, Vladimir I. Koshel, Oksana V. Sergeeva, Nadesgda M. Konovalova A24 Breast cancer prediction and prevention: Are reliable biomarkers in horizon? Shantanu Girotra, Olga Golubnitschaja A25 Flammer Syndrome and potential formation of pre-metastatic niches: A multi-centred study on phenotyping, patient stratification, prediction and potential prevention of aggressive breast cancer and metastatic disease Olga Golubnitschaja, Manuel Debald, Walther Kuhn, Kristina Yeghiazaryan, Rostyslav V. Bubnov, Vadym M. Goncharenko, Ulyana Lushchyk, Godfrey Grech, Katarzyna Konieczka A26 Innovative tools for prenatal diagnostics and monitoring: improving individual pregnancy outcomes and health-economy in EU Olga Golubnitschaja, Jan Jaap Erwich, Vincenzo Costigliola, Kristina Yeghiazaryan, Ulrich Gembruch A27 Immunohistochemical assessment of APUD cells in endometriosis Vadym M. Goncharenko, Vasyl O. Beniuk, Olga V. Kalenska, Rostyslav V. Bubnov A28 Updating personalized management algorithm of endometrial hyperplasia in pre-menopause women Vadym M. Goncharenko, Vasyl O. Beniuk, Rostyslav V. Bubnov, Olga Melnychuk A29 The personified treatment approach of polimorbid patients with periodontal inflammatory diseases Irina A. Gorbacheva, Lyudmila Y. Orekhova, Vadim V. Tachalov A30 Ukrainian experience in hybrid war – the challenge to update algorithms for personalized care and early prevention of different military injuries Olena I. Grechanyk, Rizvan Ya. Abdullaiev, Rostyslav V. Bubnov A31 Tear fluid biomarkers: a comparison of tear fluid sampling and storage protocols Suzanne Hagan, Eilidh Martin, Ian Pearce, Katherine Oliver A32 The correlation of dietary habits with gingival problems during menstruation Cenk Haytac, Fariz Salimov, Servin Yoksul, Anatoly A. Kunin, Natalia S. Moiseeva A33 Genomic medicine in a contemporary Spanish population of prostate cancer: our experience Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara, Antonia Angulo, Francisco Javier Machuca Santa-Cruz A34 Challenges, opportunities and collaborations for personalized medicine applicability in uro-oncological disease Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara A35 Metabolic hallmarks of cancer as targets for a personalized therapy John Ionescu A36 Influence of genetic polymorphism as a predictor of the development of periodontal disease in patients with gastric ulcer and 12 duodenal ulcer Alfiya Z. Isamulaeva, Anatoly A. Kunin, Shamil Sh. Magomedov, Aida I. Isamulaeva A37 Challenges in diabetic macular edema Tatjana Josifova A38 Overview of the EPMA strategies in laboratory medicine relevant for PPPM Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja, Vincenzo Costigliola A39 EPMA initiative for effective organization of medical travel: European concepts and criteria Vincenzo Costigliola, Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja A40 Design and innovation in e-textiles: implications for PPPM Anthony Kent, Tom Fisher, Tilak Dias A41 Biobank in Pilsen as a member of national node BBMRI_CZ Judita Kinkorová, Ondřej Topolčan A42 Big data in personalized medicine: hype and hope Matthias Kohl A43 The 3P approach as the platform of the European Dentistry Department (DPPPD) Anatoly A. Kunin, Natalia S. Moiseeva A44 The endometrium cytokine patterns for predictive diagnosis of proliferation severity and cancer prevention Andrii I. Kurchenko, Vasyl A. Beniuk, Vadym M. Goncharenko, Rostyslav V. Bubnov, Nadiya V. Boyko, Andriy M. Strokan A45 A monocyte-based in-vitro system for testing individual responses to the implanted material: future for personalized implant construction Julia Kzhyshkowska, Alexandru Gudima, Ksenia S. Stankevich, Victor D. Filimonov4, Harald Klüter, Evgeniya M. Mamontova, Sergei I. Tverdokhlebov A46 Prediction and prevention of adverse health effects by meteorological factors: Biomarker patterns and creation of a device for self-monitoring and integrated care Ulyana B. Lushchyk, Viktor V. Novytskyy, Igor P. Babii, Nadiya G. Lushchyk, Lyudmyla S. Riabets, Ivanna I. Legka A47 Targeting "disease signatures" towards personalized healthcare Mira Marcus-Kalish, Alexis Mitelpunkt, Tal Galili, Neta Shachar, Yoav Benjamini A48 Influence of the skin imperfection on the personal quality of life and possible tools for objective diagnosis Agnieszka Migasiewicz, Markus Pelleter, Joanna Bauer, Ewelina Dereń, Halina Podbielska A49 The new direction in caries prevention based on the ultrastructure of dental hard tissues and filling materials Natalia S. Moiseeva, Anatoly A. Kunin, Dmitry A. Kunin A50 The use of LED radiation in prevention of dental diseases Natalia S. Moiseeva, Yury A. Ippolitov, Dmitry A. Kunin, Alexei N. Morozov, Natalia V. Chirkova, Nakhid T. Aliev A51 Status of endothelial progenitor cells in diabetic nephropathy: predictive and preventive potentials Mahmood S. Mozaffari, Jun Yao Liu, Babak Baban A52 The status of glucocorticoid-induced leucine zipper protein in salivary gland in Sjögren’s syndrome: predictive and personalized treatment potentials Mahmood S. Mozaffari, Jun Yao Liu, Rafik Abdelsayed, Xing-Ming Shi, Babak Baban A53 Maximal aerobic capacity - important quality marker of health Jaroslav Novák, Milan Štork, Václav Zeman A54 The EMPOWER project: laboratory medicine and Horizon 2020 Wytze P. Oosterhuis, Elvar Theodorsson A55 Personality profile manifestations in patient’s attitude to oral care and adherence to doctor’s prescriptions Lyudmila Y. Orekhova, Tatyana V. Kudryavtseva, Elena R. Isaeva, Vadim V. Tachalov, Ekaterina S. Loboda A56 Results of an European survey on personalized medicine addressed to directions of laboratory medicine Mario Pazzagli, Francesca Malentacchi, Irene Mancini, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc, Ron H.N. van Schaik, Gerard Siest, Elvar Theodorsson, Chiara Di Resta A57 MCI or early dementia predictive speech based diagnosis techniques Matus Pleva, Jozef Juhar A58 Personalized speech based mobile application for eHealth Matus Pleva, Jozef Juhar A59 Circulating tumor cell-free DNA as the biomarker in the management of cancer patients Jiří Polívka jr., Filip Janků, Martin Pešta, Jan Doležal, Milena Králíčková, Jiří Polívka A60 Complex stroke care – educational programme in Stroke Centre University Hospital Plzen Jiří Polívka, Alena Lukešová, Nina Müllerová, Petr Ševčík, Vladimír Rohan A61 Sleep apnea and sleep fragmentation contribute to brain aging Kneginja Richter, Lence Miloseva, Günter Niklewski A62 Personalised approach for sleep disturbances in shift workers Kneginja Richter, Jens Acker, Guenter Niklewski A63 Medical travel and innovative PPPM clusters: new concept of integration Olga Safonicheva, Vincenzo Costigliola A64 Medical travel and women health Olga Safonicheva A65 Continuity of generations in the training of specialists in the field of reconstructive microsurgery Maxim Sautin, Janna Sinelnikova, Sergey Suchkov A66 Telemonitoring of stroke patients – empirical evidence of individual risk management results from an observational study in Germany Songül Secer, Stephan von Bandemer A67 Women’s increasing breast cancer risk with n-6 fatty acid intake explained by estrogen-fatty acid interactive effect on DNA damage: implications for gender-specific nutrition within personalized medicine Niva Shapira A68 Cytobacterioscopy of the gingival crevicular fluid as a method for preventive diagnosis of periodontal diseases Aleksandr Shcherbakov, Anatoly A. Kunin, Natalia S. Moiseeva A69 Use of specially treated composites in dentistry to avoid violations of aesthetics Bogdan R. Shumilovich, Zhanna Lipkind, Yulia Vorobieva, Dmitry A. Kunin, Anastasiia V. Sudareva A70 National eHealth system – platform for preventive, predictive and personalized diabetes care Ivica Smokovski, Tatjana Milenkovic A72 The common energy levels of Prof. Szent-Györgyi, the intrinsic chemistry of melanin, and the muscle physiopathology. Implications in the context of Preventive, Predictive, and Personalized Medicine Arturo Solís-Herrera, María del Carmen Arias-Esparza, Sergey Suchkov A73 Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja A74 Strategic aspects of higher medical education reforms to secure newer educational platforms for getting biopharma professionals matures Maria Studneva, Sihong Song, James Creeden, Мark Мandrik, Sergey Suchkov A75 Overview of the strategies and activities of the European Federation of Clinical Chemistry and Laboratory Medicine, (EFLM) Elvar Theodorsson, EFLM A76 New spectroscopic techniques for point of care label free diagnostics Syed A. M. Tofail A77 Tumor markers for personalized medicine and oncology - the role of Laboratory Medicine Ondřej Topolčan, Judita Kinkorová, Ondřej Fiala, Marie Karlíková, Šárka Svobodová, Radek Kučera, Radka Fuchsová, Vladislav Třeška, Václav Šimánek, Ladislav Pecen, Jan Šoupal, Štěpán Svačina2 A78 Modern medical terminology (MMT) as a driver of the global educational reforms Evgeniya Tretyak, Maria Studneva, Sergey Suchkov A79 Juvenile hypertension; the relevance of novel predictive, preventive and personalized assessment of its determinants Francesca M. Trovato, G. Fabio Martines, Daniela Brischetto, Daniela Catalano, Giuseppe Musumeci, Guglielmo M. Trovato A80 Proteomarkers Biotech George Th. Tsangaris, Athanasios K. Anagnostopoulos A81 Proteomics and mass spectrometry based non-invasive prenatal testing of fetal health and pregnancy complications George Th. Tsangaris, Athanasios K. Anagnostopoulos A82 Integrated Ecosystem for an Integrated Care model for Heart Failure (HF) patients including related comorbidities (ZENITH) José Verdú, German Gutiérrez, Jordi Rovira, Marta Martinez, Lutz Fleischhacker, Donna Green, Arthur Garson, Elena Tamburini, Stefano Cuomo, Juan Martinez-Leon, Teresa Abrisqueta, Hans-Peter Brunner-La Rocca, Tiny Jaarsma, Teresa Arredondo, Cecilia Vera, Giuseppe Fico, Olga Golubnitschaja, Fernando Arribas, Martina Onderco, Isabel Vara, on behalf of ZENITH consortium A83 Predictive, preventive and personalized medicine in diabetes onset and complication (MOSAIC project) José Verdú, Francesco Sambo, Barbara Di Camillo, Claudio Cobelli, Andrea Facchinetti, Giuseppe Fico, Riccardo Bellazzi, Lucia Sacchi, Arianna Dagliati, Daniele Segnani, Valentina Tibollo, Manuel Ottaviano, Rafael Gabriel, Leif Groop, Jacqueline Postma, Antonio Martinez, Liisa Hakaste, Tiinamaija Tuomi, Konstantia Zarkogianni, on behalf of MOSAIC consortium A84 Possibilities for personalized therapy of diabetes using in vitro screening of insulin and oral hypoglycemic agents Igor Volchek, Nina Pototskaya, Andrey Petrov A85 The innovative technology for personalized therapy of human diseases based on in vitro drug screening Igor Volchek, Nadezhda Pototskaya, Andrey Petrov A86 Bone destruction and temporomandibular joint: predictive markers, pathogenetic aspects and quality of life Ülle Voog-Oras, Oksana Jagur, Edvitar Leibur, Priit Niibo, Triin Jagomägi, Minh Son Nguyen, Chris Pruunsild, Dagmar Piikov, Mare Saag A87 Sub-optimal health management – global vision for concepts in medical travel Wei Wang A88 Sub-optimal health management: synergic PPPM-TCAM approach Wei Wang A89 Innovative technologies for minimal invasive diagnostics Andreas Weinhäusel, Walter Pulverer, Matthias Wielscher, Manuela Hofner, Christa Noehammer, Regina Soldo, Peter Hettegger, Istvan Gyurjan, Ronald Kulovics, Silvia Schönthaler, Gabriel Beikircher, Albert Kriegner, Stephan Pabinger, Klemens Vierlinger A90 Rare disease diobanks for personalized medicine Ayşe Yüzbaşıoğlu, Meral Özgüç, Member of EuroBioBank - European Network of DNA, Cell and Tissue Banks for Rare Disease

Soils swelling as a regional feature of Western Siberia

The research was to study the causes of soil swelling in Western Siberia. Studies were carried out on four stationary platforms in different climatic zones: from the sub-taiga to the southern forest-steppe. As a result of the research it was found that the level of the perched water is usually at a depth of 1-3 meters, which varies greatly depending on the season. The maximum elevation occurs at the beginning of summer, the beginning of winter – the depth of the perched water up to 3.0 meters or more. It was determined that in the sub-taiga zone of Western Siberia, perched water having a joint influence on the swelling soil; capillary fringe of perched water reaches a depth of 90 cm and the heterogeneity of the addition of the upper meter of the soil layer, which is formed by illuvial horizon with low filtration capacity. On soils with a uniform granulometric composition, despite the deeper occurrence of perched water, capillary fringe reaches a depth of 40 cm, where it has the maximum effect on the soil swelling. During construction, it is necessary under the base of roads to create protective shields of fine gravel or substandard sand, preventing the rise of water and the manifestation of bulk soils swelling

Methods with discrete sources for electromagnetic scattering by large axisymmetric particles with extreme geometries

The applicability of the discrete sources method and the null-field method with discrete sources to electromagnetic scattering by large axisymmetric particles with extreme geometries is analyzed. We present the numerical and theoretical improvements of the methods and design the null-field method with multiple spherical vector wave functions as an enhancement of the conventional null-field method for computing the optical properties of large size parameter particles. The numerical performances of the methods with discrete sources are illustrated through simulations in spheroidal and cylindrical particle cases

Creation artificial soil-ground at gardening of objects of landscape architecture in Western Siberia

Now for creation of a fertile layer usually use peat-sandy mixes in various parities, which initially do not approach for long-term development of grasses. It leads to that the grassy cover on slopes of roads, city lawns within 2–3 years perishes and is replaced natural by weeds with the vegetation which is not forming strong of sod. The carried out analysis of granulometric structure of soils on which perennial grasses grow, has shown, that as a part of artificial soil the clay containing oozy particles (<0.001 mm) should be an obligatory component. The developed optimising model has shown, that at observance of necessary conditions probably reception artificial soil of middle-loamy granulometric composition possessing optimum physical and agrochemical properties, necessary for long growth of perennial grassy vegetation. As local components it is necessary to use clay, small sand, peat in the parities received at calculation of optimising model. The parity between sand, peat and clay should make 1:2:7. For effect prevention acidification from peat and improvement of agrochemical properties it is necessary to add on 100 kg of a mix of 0.5 kg complex fertilize and 0.2 kg of a dolomitic flour that will provide nutrients to plants while in artificial soil it’s own microflora will not start to work