Intratympanic Steroid Treatment in Méniére Disease

Méniére disease (MD) is characterized by vertigo attacks, hearing loss, tinnitus, and aural fullness. Although the exact treatment of MD is lacking, several treatment options including conservative, medical, and surgical aim to control symptoms. Recently, an increasingly used treatment method called intratympanic steroid (ITS) treatment is applied to patients suffering from MD. In which step the ITS takes part for MD treatment protocol is not certain. But common wisdom is that ITS can be used in patients with intractable MD to conservative and medical treatment before applying intratympanic gentamicin and surgical treatments

Associations among high altitude, allergic rhinitis, and bronchial hyperreactivity

Allergic respiratory diseases are common public health problem. Although several treatment options, some of patients cannot manage to get satisfactory recovery. High altitude (HA) is shown as a natural additive and/or salvage therapy option for this patient group. We aimed to present the effect of HA on allergic rhinitis and bronchial hyperreactivity in company with literature

Is metabolic syndrome associated with obstructive sleep apnea in obese adolescents?

WOS: 000367581700004PubMed ID: 26156956Objective: To investigate whether there is an association between metabolic syndrome and obstructive sleep apnea syndrome (OSAS) in obese adolescents. Methods: In total, 240 pubertal children or prepubertal children older than 11 y recruited consecutively from the pediatric endocrinology unit, obesity clinic. Patients with tonsillar and adenoid hypertrophy (grade 3/4), systemic illnesses, or chronic drug usage were excluded. After anthropometric measurement and laboratory study, patients were divided into two groups according to metabolic syndrome (MS): MS and non-MS. Overnight polysomnographic evaluation was performed and 104 subjects were included for statistical analysis. The two groups were compared in terms of sleep efficiency, number of awakenings per night, oxygen desaturation index, snoring time, and obstructive/central/mixed apnea-hypopnea index (AHI). Results: Of the obese adolescents, 51 had MS and 53 did not. The AHI was >= 1 in 25 of the 53 non-MS children (47.2%) and in 25 of the 51 MS children (49%). The median obstructive AHI value was 0.9 (0.2-2.4) and total AHI was 0.9 (0.2-2.5) in the MS group; these values were 0.9 (0.25-3.55) and 0.9 (0.3-3.55), respectively, in the non-MS group. Obstructive, central, mixed, and total AHI values in the MS and non-MS groups were not statistically significantly different (p > 0.05). Conclusions: In our study, we did not find an association between MS and sleep apnea in obese adolescents

Nazal Fraktürlerin Değerlendirilmesi ve Adli Tıp Yaklaşımı

Bu çalışmada kliniğimize başvuran nazal fraktür olgularının değerlendirilmesi ve nazal fraktürlerde güncel adli tıbbi yaklaşımın sunulması amaçlanmıştır. Bu amaçla Ocak 2009-Ocak 2010 tarihleri arasında kliniğimize maksillofasyal fraktür ile başvuran olgulardan nazal fraktür tanısı alan ve tedavi edilen hastalar geriye dönük olarak değerlendirilmiştir.Çalışmamızda toplam 580 olgu saptandı. Nazal fraktür sıklığı tüm maksillofasyal kırıklar arasında %84,9’ du (n:580/683). Ortalama başvuru yaşı 28,4 idi (8 ay-84 yaş). Olguların 479’ u (%82,6) erkek iken 101 ’i (%17,4) kadındı. En sık rastlanan 3 neden etkili eylem (n:216, %37,2), düşme (n:122, %21) ve araç içi trafik kazası (n:34, %5,9) idi. Fraktürlerin 41’ i (%7,1) açık kırıkken, 539T (%92,9) kapalı fraktürlerdi. Kapalı fraktürler arasında 205 (%35,3) hastada deplase nazal fraktür saptanırken deplase olmayan nazal fraktür sayısı 334 (%57,6) idi. Nazal fraktürler maksillofasyal travmalar içinde sık rastlanılır ve erken dönem komplikasyonlar dışında uzun dönemde burun yapısında değişikliğe neden olabilir. Etyoloji sıklıkla etkili eylem, trafik veya iş kazası gibi nedenler olduğundan tüm olguların kayıt altına alınması ve bu olgularda güncel adli tıbbi yaklaşımın bilinmesi önemlidir. Anahtar kelimeler: Nazal fraktür, etyoloji, adli tı

Microanatomic analyses of extratemporal facial nerve and its branches, hypoglossal nerve, sural nerve, and great auricular nerve

Objective: To investigate microanatomic organizations of the extratemporal facial nerve and its branches, hypoglossal nerve, sural nerve, and great auricular nerve. Methods: Nerve samples were dissected in 12 postmortem autopsies, and histomorphometric analyses were conducted. Results: There was no significant difference between the right and left sides of the nerve samples for the nerve area, fascicle area, number of fascicles and average number of axons. The lowest mean fascicle number was found in the hypoglossal nerve (4.9 ± 1.4) while the highest was in great auricular nerve (11.4 ± 6.8). The highest nerve area (3,182,788 ± 838,430 μm2), fascicle area (1,573,181 ± 457,331 μm2) and axon number (14,772 ± 4402) were in hypoglossal nerve (p < 0.05). The number of axons per unit nerve area was higher in the facial nerve, truncus temporofacialis, truncus cervicofacialis and hypoglossal nerve, which are motor nerves, compared to the sural nerve and great auricular nerve, which are sensory nerves (p < 0.05). The number of axons per unit fascicle area was also higher in motor nerves than in sensory nerves (p < 0.05). Conclusion: In the present study, it was observed that each nerve contained a different number of fascicles and these fascicles were different both in size and in the number of axons they contained. All these variables could be the reason why the desired outcomes cannot always be achieved in nerve reconstruction

A Huge Cemento-Ossifying Fibroma of Paranasal Sinus: A Case Report

Cemento-ossifying fibroma is a well-bordered, slow-growing, benign fibro-osseous disease. Although its localization is generally in the mandible, it can be seen in any area of the craniofacial region. Radiology and histopathology help to diagnose the condition. Treatment is based on close observation and/or surgical excision. In this case, we report the case of a 62-year-old male patient who had a large radiological appearance, cemento-ossifying fibroma in the paranasal sinuses