The Effect of Targeted Antibiotic Prophylaxis on Lower Urinary Tract Symptoms Following Prostate Biopsy: A Prospective Randomized Trial

Objective:Targeted antibiotic prophylaxis in prostate biopsy is recommended for patients at risk due to increased complication rates seen in recent years. Lower urinary tract symptoms (LUTS) is currently one of the most prevalent complications with a rate of more than 40%. The study examined the effects of targeted antibiotic prophylaxis on biopsy-related LUTS and to compare the results with standard prophylaxis.Materials and Methods:A total of 240 patients were included in the study, 120 of whom had been administered targeted antibiotic prophylaxis and 120 of whom had received ciprofloxacin treatment between January 2021-Januray 2023. Patients’ results before the procedure, on the 7th day, and in the first month were prospectively recorded and compared.Results:While Qmax mean values were measured as 18.3±5.1 mL/s in the targeted prophylaxis group and 17.4±4.6 mL/s in the control group (p=0.157) before the procedure, these values were found to be 14.6±3.3 mL/s and 11.7±4.1 mL/s (p<0.001) on the 7th day and 16.8 16.8±4.3 mL/s and 14.9±3.5 mL/s (p=0.013) in first month, respectively. IPSS mean scores of the groups were calculated as 16.8±4.3 mL/s and 14.9±3.5 mL/s (p=0.013) before the procedure, respectively, while these scores were found to be 18.12±6.1 and 22.97±7.4 (p<0.001) on the 7th day and 17.5±5.5 and 22.8±7.5 (p<0.001) in the first month, respectively.Conclusion:In this study, we found that targeted antibiotic prophylaxis had a significant effect on preventing biopsy-related LUTS. We believe that routine application of targeted antibiotic prophylaxis can be effective in reducing the rates of biopsy-related LUTS

Our results of pnomotic lithotripcy and rijit ureteroscopy in ureteral stones

Amaç: Üreter taş tanısı alan olgularda rijit üreteroskopi ve pnomotik litotripsinin etkinli- ğini incelemek. Gereç ve Yöntemler: Üreter taşı nedeniyle rijit üreteroskopi ve pnomotik litotripsi uygulanan 246 olgunun dosyaları geriye dönük incelendi. Sonuçlar tedaviden 3 ay sonra yapılan üriner ultrasonografi ve/veya intravenöz piyelografi ile değerlendirildi. Taş yerleşimine göre tedavi başarısı ve komplikasyon oranları karşı- laştırıldı. Bulgular: Olguların ortalama yaşı 45,0 yıl(dağılım 15-81), 131(%53,2)i erkek, 105(%42,8)i kadın idi. Taşların 114(%46,3)ü sağ, 131(%53,2)i sol, 1(%4,0)i ise bilateral üreter yerleşimliydi. Ortalama taş boyutu 8,75(dağılım 5-35) mm olarak bulundu. Toplam taşsızlık oranı totalde %88,1(distal üreterde %96.7, orta üreterde %87.4 ve proksimal üreterde %80.2) idi. Toplam komplikasyon ise %6.5(alt, orta ve üst üreterde sırasıyla %3.2, %6.4 ve %10.1) olarak gelişti. En sık peroperatif komplikasyon; %2.6 enfeksiyon, %1.1 mukozal hasar ve %4 üreter perforasyonu iken, en sık geç komplikasyon olguların %1.1inde üreter darlığı idi. Üreter taşı olan olgular taş büyüklüğüne göre Grup 1 10 mm (n114) ve Grup 2 10 mm (n132) olarak belirlendi. Grup 1de üreter yerleşimine göre taşsızlık oranları yüksek (proksimal %88, orta %92, distal %100 ve totalde %93.3) ve komplikasyon oranı düşük (%3.4) olarak gözlendi. Sonuç: Üreter taşlarının rijit üreteroskopi ve pnomotik litotripsi ile tedavisi tüm yerleşimlerdeki üreter taşlarında yüksek başarı, hızlı taşsızlık ve düşük komplikasyon oranlarıyla başarılı bir şekilde uygulanabilmektedir. Rijit üreteroskopi ve pnomotik litotripsi ile tedavi edilen alt üreter taşlarında taş büyüklüğü toplam taşsızlık ve komplikasyon oranlarını etkilememektedir.Objective: In patients with a diagnosis of ureteral calculi with rigid ureteroscopy and pneumatic lithotripsy evaluate the effectiveness of. Materials and Methods: Due to ureteral stone rigid ureteroscopy and pneumatic lithotripsy applied retrospectively reviewed the files of 246 cases. Results after 3 months of treatment with ultrasound urinary and /or evaluated with intravenous pyelography. According to Stone residential treatment success and complication rates were compared. Results: Mean age was 45.0 years (range 15-81), 131(53.2 %) were male, 105(42.8 %) were female. Stone of the 114(46.3%) to the right and 131(53.2 %) left , one(4.0 %)s bilateral ureter. Average stone size was 8.75(range 5-35) mm respectively. In total 88.1 % of the total stone-free rate (96.7 % in the distal ureter, middle ureter and proximal ureter was 87.4% and 80.2 %) respectively. Total complication was 6.5% (lower, middle and upper ureter, respectively, 3.2%, 6.4% and 10.1%) has evolved as. The most common intraoperative complication of infection of 2.6%, 1.1% and 4%, ureteral perforation, while mucosal damage, the most common late complication of patients 1.1% were in the ureteral stricture. Patients with ureteral stone by stone size group 1 10 mm (n 132), respectively. According to the placement in group 1 generates higher stone-free rates (88% proximal, middle 92%, and 93.3 % in the distal and total 100%) and low complication rate (3.4%) was observed. Conclusion: Rigid ureteroscopy and pneumatic lithotripsy of ureteral stones treated with ureteral stones in all residential high success and low complication rates and quick stone clearance can be applied successfully. Rigid treated with ureteroscopy and pneumatic lithotripsy lower ureteral stone size does not affect the overall stone free and complication rates

A rare complication of a malleable penile prosthesis: migration to the thigh region

Guner, Bayram/0000-0001-7602-2255WOS: 000326878200038PubMed: 24013620Dear editor, Here, we discuss an unusual prosthesis migration to the thigh region. Because the incidence of erectile dysfunction increases in parallel with the prevalence of neurological, degenerative and vascular diseases among elderly men, the use of penile prostheses is common in this age group. Still, cylinder migration following the implantation of a malleable penile prosthesis is a very rare entity

Autosomal Dominant Polycystic Kidney Disease Patient Specified Bilateral Renal Mass: A Case Report

WOS: 000396411700019Hereditary cystic lesions of the kidney cysts nonherediter lesion with a wide range. They may be the only finding in the form of extrarenal renal cysts may also be part of a clinical syndrome. For this reason, multi-disciplinary approach brings with cystic lesions in the different units. Autosomal dominant polycystic kidney disease, kidney different sizes and numbers of both systemic and hereditary disease that manifests itself in the form of cystic changes. Hereditary and acquired cystic lesions on the basis of some of the rare tumor association is determined in several studies. Here are diagnosed with autosomal dominant polycystic kidney disease, abdominal pain because of a mass in the last six months, physical examination, radiological and laboratory findings were diagnosed with bilateral renal tumors are uncommon and the right renal mass nephron-sparing surgery, the patients with left renal mass followed with active surveillance discussed in the current literature

An artificial bee colony algorithm approach for unrelated parallel machine scheduling with processing set restrictions, job sequence-dependent setup times, and due date

The problem dealt with in this study has job sequence-dependent setup times under suitable machine constraints and due date constraints. The performance criterion for this problem is to minimize the sum of makespan and total tardiness. In the literature, an application of ABC algorithm for the problems which includes all the properties that we have dealt has not been discussed. Because there is no appropriate test data, a real-life data was collected from a factory. In this study, a new approach has been proposed for the solution with meta-heuristics of unrelated parallel machine scheduling problems which is a combinatorial problem. This new neighborhood approach provides different machine assignments for every candidate job sequences. This approach is used by integrating into ABC and GA. To evaluate the performances of the algorithms, the real-life problem was solved by using ABC and GA algorithms under similar conditions. It was found that all jobs can be completed in two shifts without the need for a third shift. Computational results show that ABC algorithm has better performance than GA

Polygamy, sexual behavior in a population under risk for prostate cancer diagnostic: an observational study from the Black Sea Region in Turkey

ABSTRACT Aim: Although prostate cancer (PCa) is the most common cancer type in men, a replaceable risk factor has not yet been established. In our study, we assessed the relationship between the number of sexual partners, age of first sexual experience and age of first masturbation and prostate cancer incidence. Materials and Methods: In Ordu University Department of Urology between January 2013 and September 2016, in PSA elevation and rectal examination, patients with prostate biopsy were evaluated due to nodule palpation in the prostate. At younger ages and at present, their first masturbation ages, first sexual debut ages, and total sexual partner numbers were recorded. The correlation between the obtained data and PCa frequency was evaluated. Results: The study included 146 patients with PCa identified on biopsy and 171 patients with benign biopsy results who answered the questions. 66.7% of the ones whose biopsy results were benign and 40.6% of cancer suspects had only one sexual partner. The median number of sexual partners was 1±4 (1-100) in the benign group and 2±6 (1-500) in the malignant group (p=0.039). There was a negative correlation between age of first sexual debut and number of partners (r: −0,479; p <0.001). Conclusion: In our study, it appears that there may be an association between the number of sexual partners and prostate cancer in the patient group with PSA level above 4ng/mL. Avoidance of sexual promiscuity or participation in protected sex may be beneficial to protect against prostate cancer

Is there a difference between Parkinson disease patients and a control group in terms of urinary symptoms and quality of life?

WOS: 000393331000009PubMed ID: 28081354Background/aim: The aim of this study is to research whether urinary symptoms and disruption of quality of life observed in Parkinson disease patients are different than those of their healthy peers. Additionally, whether these complaints were affected by characteristics such as age at onset of Parkinson disease, sex, disease duration, and severity was investigated. Materials and methods: This study comprised a total of 79 individuals, 39 Parkinson patients and a control group of 40 individuals. Parkinson diagnosis was provided by a neurology expert according to the UK Parkinson's Disease Society Brain Bank Criteria. All patients were evaluated by a urologist with the International Prostate Symptom Score (IPSS) and an overactive bladder (OAB) questionnaire. Results: Compared with the control group, the Parkinson patient group had statistically significantly higher rates of urological complaints (P < 0.001), irritative symptoms (P < 0.001), voiding symptoms (P < 0.001), OAB score (P < 0.001), IPSS total score (P = 0.007), and treatment requirements (P < 0.001). Conclusion: Urologic complaints were observed more frequently in the Parkinson patient group compared to the control group. Another important result of this study is that in the Parkinson patient group there was no difference found between urologic complaints in terms of sex