Serologic profile of serum antibody reactivity to SV40 mimotopes VP1 B (A) and VP2/3 C (B) and VPs B+C (C).

<p>Immunologic data are from serum samples from Multiple Sclerosis patients (MS), Healthy Subjects (HS1), Other Inflammatory Neurologic Diseases (OIND), Non-Inflammatory Neurologic Diseases (NIND) and Healthy subjects (HS2). Results are presented as values of optical density (OD) readings at λ 405 nm, of serum samples diluted at 1∶20, detected in indirect ELISA. In scatter dot plotting, each plot represents the dispersion of OD values to a mean level indicated by the line inside the scatter with Standard Error Mean (SEM) for each group of subjects analyzed. A) The mean OD of sera (VP B ± Std Error) in MS (0.32±0.02) were lower than that in HS1 (0.50±0.02) and in OIND (0.67±0.04). Moreover the mean OD of sera in OIND were higher than that in NIND (0.32±0.02) and HS2 (0.46±0.02). The mean OD of sera in NIND were lower than that in HS2. B) The mean OD of sera (VP C ± Std Error) in MS (0.26±0.03) were lower than that in HS1 (0.43±0.02). C) The mean OD of sera (VPs B+C ± Std Error) in MS (0.29±0.02) were lower than that in HS1 (0.46±0.02) and in OIND (0.49±0.03). Moreover, the mean OD of sera in OIND were higher than that in NIND (0.34±0.02). The mean OD in NIND were lower than that in HS2 (0.43±0.02) and in OIND sera. Statistical analysis was performed using Anova and Newman-Keuls Comparison test. (**<i>P</i><0.001; °<i>P</i><0.01).</p

Prevalence of immunoglobulin G antibodies reacting with Simian Virus 40 (SV40) viral protein (VP) mimotopes in serum samples of patients affected by MS, OIND, NIND and HS∧.

<p>∧Human sera were from patients affected by multiple sclerosis (MS), other inflammatory neurologic diseases (OIND), non-inflammatory neurologic diseases (NIND) and healthy subjects (HS1), (HS2).</p><p>*The prevalence of SV40 antibodies in MS patients is statistically significant lower that those detected in NIND patients (<i>P</i> = 0.0254) and in HS1 (<i>P</i> = 0.001), whereas no significant was the different prevalence detected in MS and OIND patients (<i>P</i>>0.05).</p><p>** The prevalence of SV40 antibodies in OIND patients is statistically significant lower that those detected in HS2 (<i>P</i> = 0.0403). The different prevalence of SV40 antibodies between the cohorts of NIND patients was not significant compared with the HS2 (<i>P</i>>0.05). Statistical analysis was performed using the χ² test.</p><p>Prevalence of immunoglobulin G antibodies reacting with Simian Virus 40 (SV40) viral protein (VP) mimotopes in serum samples of patients affected by MS, OIND, NIND and HS∧.</p

Residential Mobility of Prague Population with Focus on Ethnic Minorities

Since 1989, Czechia has undergone many changes. Increasingly important part of Czech society is represented by foreign inhabitants, who - most often - move to Prague. The capital city is target of economic migrants but also of those foreigners who seek a new home. The aim of the diploma thesis is to get to know spatial patterns of migration of population in Prague between 1992 and 2011 and to explain geographical causes of migration. The first part of the thesis discusses theoretical approaches dealing with mobility, especially with migration and residential mobility. Next chapter introduces development of migration of population in Prague and summarizes basic findings about the most numerous groups of foreigners living in the capital city. Based on data from registers of migration, general trends in population migration are identified, then, migration activity of Prague inhabitants by citizenship is analyzed. Case study of urbanistic district Nové Butovice-západ in the final part of the thesis verifies, by triangulation of research methods, the reliability of statistical data on numbers and movement of foreigners in Prague and analyzes the influence of immigration of Russian citizens on changing social environment of the studied locality

Demographic, clinical and radiological characteristics in 62 patients with acute ischemic stroke.

<p>Demographic, clinical and radiological characteristics in 62 patients with acute ischemic stroke.</p

Semi-quantitative and quantitative CT perfusion (CTP) Alberta Stroke Program Early CT Score (ASPECTS) optimal values for recognizing AIS patients with good clinical outcome (mRS<2 at 3 months) as calculated using Receiver Operating Characteristic (ROC) curves.

<p>Semi-quantitative and quantitative CT perfusion (CTP) Alberta Stroke Program Early CT Score (ASPECTS) optimal values for recognizing AIS patients with good clinical outcome (mRS<2 at 3 months) as calculated using Receiver Operating Characteristic (ROC) curves.</p

Comparison between semi-quantitative (white boxes) and quantitative (grey boxes) ASPECTS for cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and CT perfusion (CTP) mismatch.

<p>The boundaries of the box represent the 25th-75th quartile. The line within the box indicates the median. The whiskers above and below the box correspond to the highest and lowest values, excluding outliers.</p

Semi-quantitative and quantitative CT perfusion (CTP) Alberta Stroke Program Early CT Score (ASPECTS) in 62 acute ischemic stroke patients categorized according to hemorrhagic transformation (HT) and clinical outcome.

<p>Semi-quantitative and quantitative CT perfusion (CTP) Alberta Stroke Program Early CT Score (ASPECTS) in 62 acute ischemic stroke patients categorized according to hemorrhagic transformation (HT) and clinical outcome.</p

Inclusion and exclusion flow chart of the study.

<p>Inclusion and exclusion flow chart of the study.</p

Non-constrast CT, baseline source and average CT perfusion images, cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT) maps at ganglionic (A-F) and supraganglionic (G-L) axial ASPECTS levels.

<p>Multiple circular regions of interest (ROIs) larger than 1 cm² placed freehand in the affected hemisphere and automatically reflected into homologous regions of the contralateral hemisphere were used to measure CBF, CBV and MTT absolute values from the corresponding functional maps in ASPECTS regions at ganglionic (anterior middle cerebral artery cortex, middle cerebral artery cortex lateral to insular ribbon, posterior middle cerebral artery cortex, insula, caudate nucleus, lentiform nucleus and internal capsule) and supraganglionic (anterior, lateral, and posterior middle cerebral artery cortical territories immediately superior to the previous ones, rostral to basal ganglia) sections.</p

Supplemental Material - Clinical Features, Non-Contrast CT Radiomic and Radiological Signs in Models for the Prediction of Hematoma Expansion in Intracerebral Hemorrhage

Supplemental Material for Clinical Features, Non-Contrast CT Radiomic and Radiological Signs in Models for the Prediction of Hematoma Expansion in Intracerebral Hemorrhage by Zejia Frank Chen, Liying Zhang, André M Carrington, Rebecca Thornhill, Olivier Miguel, Angela M Auriat, Nima O Fard, Shiva Hiremath, Vered Tshemeister Abitbul, Dar Dowlatshahi, Andrew Demchuk, David Gladstone, Andrea Morotti, Ilaria Casetta, Enrico Fainardi, Thien Huynh, Marah Elkabouli, Zoé Talbot, Gerd Melkus, and Richard I Aviv in Canadian Association of Radiologists Journal</p