Cedar control by individual scorched-tree ignition following fire

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Proton Beam Energy Characterization

Introduction The Los Alamos Isotope Production Facility (IPF) is actively engaged in the development of isotope production technologies that can utilize its 100 MeV proton beam. Characterization of the proton beam energy and current is vital for optimizing isotope production and accurately conducting research at the IPF. Motivation In order to monitor beam intensity during research irradiations, aluminum foils are interspersed in experimental stacks. A theoretical yield of 22Na from 27Al(p,x)22Na reactions is cal-culated using MCNP6 (Monte Carlo N-Particle), TRIM (Transport of Ions in Matter), and Andersen & Ziegler (A&Z) [1] computational models. For some recent experiments, experimentally measured activities did not match computational predictions. This discrepancy motivated further experimental investigations including a direct time-of-flight measurement of the proton beam energy upstream of the target stack. The Isotope Production Program now tracks the beam energy and current by a complement of experimental and computational methods described below. Material and Methods A stacked-foil activation technique, utilizing aluminum monitor foils [2] in conjunction with a direct time-of-flight measurement helps define the current and energy of the proton beam. Theoretical yields of 22Na activity generated in the Al monitor foils are compared with experimental measurements. Additionally, MCNP, TRIM, and A&Z computational simulations are compared with one another and with experimental data. Experimental Approach Thin foils (0.254mm) of high purity aluminum are encapsulated in kapton tape and stacked with Tb foils in between aluminum degraders. Following irradiation, the Al foils are assayed using γ-spectroscopy on calibrated HPGe detectors in the Chemistry Division countroom at LANL. We use the well-characterized 27Al(p,x)22Na energy dependent production cross section [3] to calculate a predicted yield of 22Na in each foil. Details of the experimental activity determination and associated uncertainties have been addressed previously [4]. The nominally stated beam parameters are 100 MeV and 100–120 nA for the foil stack irradiation experiments. Time-of-flight measurements performed in the month of January 2014 revealed beam energy of 99.1 ± 0.5 MeV. Computational Simulations Andersen & Zeigler (A&Z) is a deterministic method and also the simplest of the three com-putational methods considered. While the mean energy degradation can be calculated using the A&Z formalism, the beam current attenuation cannot. Consequentially, A&Z will also lack the ability to account for a broadening in the beam energy that a stochastic method affords. Additionally, A&Z does not account for nuclear recoil or contributions from secondary interactions. TRIM uses a stochastic based method to calculate the stopping range of incident particles applying Bethe-Block formalisms. TRIM, like A&Z, does not include contributions from nuclear recoil or contributions from secondary interactions. Computationally, TRIM is a very expensive code to run. TRIM is able to calculate a broadening in the energy of the beam; however, beam attenuation predictions are much less reliable. TRIM determines the overall beam attenuation in the whole stack to be less than one percent, whereas 7–10 % is expected. MCNP6 is arguably the most sophisticated approach to modeling the physics of the experiment. It also uses a stochastic procedure for calculation, adopting the Cascade-Exciton Model (CEM03) to track particles. The physics card is enabled in the MCNP input to track light ion recoils. Contributions from neutron and proton secondary particle interactions are included, although their contribution is minimal. For both MCNP and TRIM, the proton beam is simulated as a pencil beam. To find the current, an F4 volumetric tally of proton flux from MCNP simulation is matched to the experimental current for the first foil in the stack. Subsequent foil currents are calculated relative to the first foil based on MCNP predictions for beam attenuation. The equation used for calculating the current from the experi-mental activity is [5]: where: is the cross section for the process, [mbarns] is the atomic mass of the target [amu] is the is the number of product nuclei pre-sent at End-of-Bombardment is the average beam current, [μA] is the density of the target material, [g/cc] is the target thickness, [cm] is the decay constant, [s−1] is the irradiation time, [s] For each foil in the experimental stack, we also have a statistically driven broadening of the incident energy. The beam energy is modeled as a Gaussian distribution, with the tallies for each energy bin determining the parameters of the fit. TABLE 1 and FIG. 3 summarize the mean energy and standard deviation of the energy for each aluminum monitor foil. To address the energy distribution, we calculate an effective or weighted cross-section. It is especially important to account for energy broadening in regions where the associated excitation function varies rapidly. In the excitation function, we see a strong variation in the energy range from 30–65 MeV, the energy region cov-ered by the last 3 foils in the stack. Cross section weighting also accounts for the mean energy variation within each foil. The excitation function will overlay the Gaussian shaped flux distribution, giving rise to a lateral distribution where incrementally weighted values of the cross section are determined by the flux tally of the corresponding energy bin. With the effective cross section and the current at each of the foils, it is straight-forward to calculate the number of 22Na atoms created and the activity of each foil using the previously stated equation. Results and Conclusion The general trend in the amount of activity produced follows the shape of the excitation func-tion for the 27Al(p,x)22Na reaction. Small shifts in the incident energy upstream trickle down to produce much more pronounced shifts in the energy range of foils towards the back of the foil stack. The characteristic “rolling over” of the activity seen in the experimental foils indicates that the 6th foil must be in the energy region below 45 MeV, where the peak of the excitation function occurs. Conservatively, computational simulations are able to accurately determine the proton beam’s energy for an energy range from 100 to 50 MeV. As the beam degrades below 50 MeV, computa-tional simulations diverge from experimentally observed energies by over-predicting the energy. This observation has been noted in past studies [6,7] that compare the stacked foil technique with stopping-power based calculations. A complement of experimental and computational predictions allows for energy determinations at several points within target stacks. While this study focuses on an Al-Tb foil stack, the analysis of a similar Al-Th foil stack resulted in the same conclusions. Although we do not have a concurrent time-of-flight energy measurement at the time of the foil stack experiments, it is reasonable to assume that the energy at the time of the stacked foil experiments was also lower than the assumed energy of 100 MeV. Computational simulations developed in this work firmly support this assumption. Various computational models are able to predict with good agreement the energy as a function of depth for complex foil stack geometries. Their predictions diverge as the beam energy distribution broadens and statistical uncertainties propagate. A careful inspection of the codes reveals that these discrepancies likely originate from minute differences between the cross sections and stopping power tables that MCNP and TRIM/A&Z use respectively

Single center experience on dosing and adverse events of recombinant factor seven use for bleeding after congenital heart surgery

There are limited data on the relationship between the administered dose of recombinant factor seven (rFVIIa) and the development of adverse clinical outcomes after congenital heart surgery. This single institution case series reports on dosing, adverse events, and blood product usage after the administration of rFVIIa in the congenital heart surgery patient population. A retrospective review identified 16 consecutive pediatric patients at an academic, free-standing, children’s hospital who received rFVIIa to curtail bleeding following congenital heart surgery between April 2004 and June 2012. Patients were assessed for survival to hospital discharge versus in-hospital mortality and the presence or absence of a major neurological event during inpatient hospitalization. The median age at surgery was 6.8 months (range: 3 days–42 years). Seven patients (44%) survived to hospital discharge and nine patients (56%) died. The cause of mortality included major neurological events (44%), uncontrolled bleeding (33%), and sepsis (23%). Eight patients (50%) required extracorporeal membrane oxygenation support following congenital heart surgery. The median cumulative rFVIIa dose administered was 97 mcg/kg, and the median cumulative amount of blood products administered was 452 ml/kg. In conclusion, this case series underscores the need to prospectively evaluate the effect that rFVIIa has on patient survival and the incidence of adverse events, including thrombotic and major neurological events, in congenital heart surgery patients. Ideally, a randomized, multicenter study would provide the sufficient numbers of patients and events to test these relationships

Eastern redcedar control and management - Best management practices to restore Oklahoma's ecosystems

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Eastern redcedar control and management - Best management practices to restore Oklahoma's ecosystems

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Lorentzian spin foam amplitudes: graphical calculus and asymptotics

The amplitude for the 4-simplex in a spin foam model for quantum gravity is defined using a graphical calculus for the unitary representations of the Lorentz group. The asymptotics of this amplitude are studied in the limit when the representation parameters are large, for various cases of boundary data. It is shown that for boundary data corresponding to a Lorentzian simplex, the asymptotic formula has two terms, with phase plus or minus the Lorentzian signature Regge action for the 4-simplex geometry, multiplied by an Immirzi parameter. Other cases of boundary data are also considered, including a surprising contribution from Euclidean signature metrics.Comment: 30 pages. v2: references now appear. v3: presentation greatly improved (particularly diagrammatic calculus). Definition of "Regge state" now the same as in previous work; signs change in final formula as a result. v4: two references adde