1,170 research outputs found
Expanding Opportunity for All: Moving Past Zero-Sum Notions of Affirmative Action to Promote Both Freedom and Equality
Reviewing: Joseph Fishkin, Bottlenecks: A New Theory of Equal Opportunity (Oxford University Press 2016)
Constructing Courts: Judicial Institutional Change Embedded in Larger Political Dynamics
Reviewing Justin Crowe, Building the Judiciary: Law, Courts and the Politics of Institutional Development (2012) and Jed Handelsman Shugerman, The People\u27s Courts: Pursuing Judicial Independence in America (2012)
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The role of stimulus and response generalization in a two choice reaction time task.
PsychologyDoctor of Philosophy (Ph.D.
Tripping over the other: Could psychedelics increase empathy?
There is increasing evidence that psychedelic-assisted psychotherapy is effective for a range of psy-chological conditions. There are likely numerous mechanisms of action that contribute to these clinicaleffects. One such mechanism of action might involve psychedelics increasing levels of empathicfunctioning. This paper synthesises research concerning the relationship between psychedelics andempathy, emphasising neuroscientific and clinical contexts. We conclude that neuropsychological andclinical evidence imply psychedelics could lead to increased empathic functioning. The effects of psy-chedelics on the 5-HT system, default mode network, neural connectivity and ego dissolution areimplicated in these changes. Changes in empathic functioning also likely relate to increases in thepersonality trait of openness associated with psychedelic drug use, which is well documented. Increasedempathic function likely has clinical implications, leading to increased social connectedness as well asprosocial attitudes and behaviours more broadly
Unclamped hand-assisted laparoscopic partial nephrectomy for predominantly endophytic renal tumors
PURPOSE: To describe our initial experience with unclamped laparoscopic hand-assisted partial nephrectomy for predominantly endophytic renal masses in the setting of relative contraindication to warm ischemia.
MATERIALS AND METHODS: Unclamped laparoscopic hand-assisted partial nephrectomy was performed on eight consecutive patients from June 2009 to March 2010. All patients had predominantly endophytic renal masses with a preferential enhancing rim noted on the pre-operative computed tomography. The unclamped hand-assisted approach was utilized for no warm ischemia, minimal blood loss, and enhanced visualization of the tumor bed with improved operative exposure.
RESULTS: Mean age of the participants was 55.8 years. All patients underwent unclamped hand-assisted partial nephrectomy (ie, zero ischemia). Mean estimated blood loss was 368.8 cc (range, 100 to 800 cc) and mean operation time was 236.9 minutes (range, 175 to 272 minutes). There were no intra-operative complications and no open conversions. There was one grade II (ileus with small pneumothorax) and one grade IV (pulmonary embolism) in the 90-day peri-operative period. There was one positive surgical margin, which was recognized intra-operatively.
CONCLUSION: While our results are preliminary, we feel this technique provides superior visualization and adequate hemostasis while preserving oncologic efficacy and renal function in this patient population
Fucking With Dignity: Public Sex, Queer Intimate Kinship, and How the AIDS Epidemic Bathhouse Closures Constituted a Dignity Taking
In the name of public health, authorities in San Francisco and New York City pursued the closure of gay bathhouses in 1984 and 1985, respectively. We challenge the dominant historical narrative that justified these closings, and through that challenge, we argue that these closures constituted a dignity taking against gay and queer-identified men. Bathhouses were not simply dens of impersonal anonymous sex. They were critical sites of community development and queer kinship. Many governing authorities neither considered the value of these institutions nor grappled with queer understandings of space, contact, intimacy, and belonging. The debates and the closures that followed did substantial cultural and political work to render gay men culpable for their own community’s sudden and relentless demise. As such, these closures were part of a larger anti-gay and anti-HIV cultural discourse that dehumanized and infantilized men who have sex with other men. The bathhouse closings fostered and perpetuated a narrative of culpability, ignited intense divisions within the gay and lesbian communities, and produced within gay men a deep distrust and even fear of governing institutions and of one another. We suggest that this failure to engage with queer logic is ongoing and limits contemporary efforts of dignity restoration that include same-sex marriage recognition. Given the limits of dignity, we conclude by offering some thoughts on what queer dignity restoration might entail
Plasticity, and Its Limits, in Adult Human Primary Visual Cortex
There is an ongoing debate about whether adult human primary visual cortex (V1) is capable of large-scale cortical reorganization in response to bilateral retinal lesions. Animal models suggest that the visual neural circuitry maintains some plasticity through adulthood, and there are also a few human imaging studies in support this notion. However, the interpretation of these data has been brought into question, because there are factors besides cortical reorganization, such as the presence of sampling bias and/or the unmasking of task-dependent feedback signals from higher level visual areas, that could also explain the results. How reasonable would it be to accept that adult human V1 does not reorganize itself in the face of disease? Here, we discuss new evidence for the hypothesis that adult human V1 is not as capable of reorganization as in animals and juveniles, because in adult humans, cortical reorganization would come with costs that outweigh its benefits. These costs are likely functional and visible in recent experiments on adaptation — a rapid, short-term form of neural plasticity — where they prevent reorganization from being sustained over the long term
Psychedelic trip sitting, dosages and intensities: Supplementing clinical studies with anecdotal reports
Background and aims: Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research. This study extracts forum data on psychedelic substances, dosages, and administration routes, categorising and analysing self-reported consumption to inform care services and guide clinical work with psychedelics. Methods: Posts (n = 660) from online psychedelic forums (The Shroomery and DMT Nexus) on \u27trip sitting\u27 were analysed. Using a Delphi-style expert panel review facilitated by LE, we created drug weight and intensity charts (threshold, light, common, strong and heavy dosages) for psychedelics discussed in these posts. The psychedelic substance, dosage intensity and route of administration [ROA] (smoked/vaporised, oral, injected, insufflated and undisclosed) frequencies and exploring correlations with perceived need for assistance from a psychedelic carer were mapped and correlated with perceived need for psychedelic care. Results: Psychedelics appearing in our data were 5-MeO-DMT, ayahuasca, changa, LSA, LSD and psilocybin. There was greater commonality between clinical studies and \u27common\u27 doses determined through the Delphi method, for more extensively researched substances like LSD and psilocybin. Many posts indicated opinions that psychedelic care was unnecessary or optional for consumers, particularly for LSD and LSA. 5-MeO-DMT was strongly associated with a perceived need for care. A correlation was identified between greater psychedelic purity, dosage intensity, and a perceived need for care. Oral administration, the most common ROA, showed lower dosage intensity. Conclusion: More research is needed to understand factors influencing psychedelic care practices. Educational information, emphasizing risk management strategies, should be provided to psychedelic consumers, emphasising psychedelic products and administration methods more likely to be dosed at a strong or heavy intensity
Promoted Metals Combustion at Ambient and Elevated Temperatures
Promoted combustion testing of materials, Test 17 of NASA STD-6001, has been used to assess metal propensity to burn in oxygen rich environments. An igniter is used at the bottom end of a rod to promote ignition, and if combustion is sustained, the burning progresses from the bottom to the top of the rod. The physical mechanisms are very similar to the upward flammability test, Test 1 of NASA STD-6001. The differences are in the normal environmental range of pressures, oxygen content, and sample geometry. Upward flammability testing of organic materials can exhibit a significant transitional region between no burning to complete quasi-state burning. In this transitional region, the burn process exhibits a probabilistic nature. This transitional region has been identified for metals using the promoted combustion testing method at ambient initial temperatures. The work given here is focused on examining the transitional region and the quasi-steady burning region both at conventional ambient testing conditions and at elevated temperatures. A new heated promoted combustion facility and equipment at Marshall Space Flight Center have just been completed to provide the basic data regarding the metals operating temperature limits in contact with oxygen rich atmospheres at high pressures. Initial data have been obtained for Stainless Steel 304L, Stainless Steel 321, Haynes 214, and Inconel 718 at elevated temperatures in 100-percent oxygen atmospheres. These data along with an extended data set at ambient initial temperature test conditions are examined. The pressure boundaries of acceptable, non-burning usage is found to be lowered at elevated temperature
Mechanical Impact Testing: A Statistical Measurement
In the decades since the 1950s, when NASA first developed mechanical impact testing of materials, researchers have continued efforts to gain a better understanding of the chemical, mechanical, and thermodynamic nature of the phenomenon. The impact mechanism is a real combustion ignition mechanism that needs understanding in the design of an oxygen system. The use of test data from this test method has been questioned due to lack of a clear method of application of the data and variability found between tests, material batches, and facilities. This effort explores a large database that has accumulated over a number of years and explores its overall nature. Moreover, testing was performed to determine the statistical nature of the test procedure to help establish sample size guidelines for material characterization. The current method of determining a pass/fail criterion based on either light emission or sound report or material charring is questioned
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