88 research outputs found

    Modelling waving crops using large-eddy simulation: Comparison with experiments and a linear stability analysis

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    International audienceIn order to investigate the possibility of modelling plant motion at the landscape scale, an equation for crop plant motion, forced by an instantaneous velocity field, is introduced in a large-eddy simulation (LES) airflow model, previously validated over homogeneous and heterogeneous canopies. The canopy is simply represented as a poroelastic continuous medium, which is similar in its discrete form to an infinite row of identical oscillating stems. Only one linear mode of plant vibration is considered. Two-way coupling between plant motion and the wind flow is insured through the drag force term. The coupled model is validated on the basis of a comparison with measured movements of an alfalfa crop canopy. It is also compared with the outputs of a linear stability analysis. The model is shown to reproduce the well-known phenomenon of honami which is typical of wave-like crop motions on windy days. The wavelength of the main coherent waving patches, extracted using a bi-orthogonal decomposition (BOD) of the crop velocity fields, is in agreement with that deduced from video recordings. The main spatial and temporal characteristics of these waving patches exhibit the same variation with mean wind velocity as that observed with the measurements. However they differ from the coherent eddy structures of the wind flow at canopy top, so that coherent waving patches cannot be seen as direct signatures of coherent eddy structures. Finally, it is shown that the impact of crop motion on the wind dynamics is negligible for current wind speed values. No lock-in mechanism of coherent eddy structures on plant motion is observed, in contradiction with the linear stability analysis. This discrepancy may be attributed to the presence of a nonlinear saturation mechanism in LES. © 2010 Cambridge University Press

    Sporadic Infantile Epileptic Encephalopathy Caused by Mutations in PCDH19 Resembles Dravet Syndrome but Mainly Affects Females

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    Dravet syndrome (DS) is a genetically determined epileptic encephalopathy mainly caused by de novo mutations in the SCN1A gene. Since 2003, we have performed molecular analyses in a large series of patients with DS, 27% of whom were negative for mutations or rearrangements in SCN1A. In order to identify new genes responsible for the disorder in the SCN1A-negative patients, 41 probands were screened for micro-rearrangements with Illumina high-density SNP microarrays. A hemizygous deletion on chromosome Xq22.1, encompassing the PCDH19 gene, was found in one male patient. To confirm that PCDH19 is responsible for a Dravet-like syndrome, we sequenced its coding region in 73 additional SCN1A-negative patients. Nine different point mutations (four missense and five truncating mutations) were identified in 11 unrelated female patients. In addition, we demonstrated that the fibroblasts of our male patient were mosaic for the PCDH19 deletion. Patients with PCDH19 and SCN1A mutations had very similar clinical features including the association of early febrile and afebrile seizures, seizures occurring in clusters, developmental and language delays, behavioural disturbances, and cognitive regression. There were, however, slight but constant differences in the evolution of the patients, including fewer polymorphic seizures (in particular rare myoclonic jerks and atypical absences) in those with PCDH19 mutations. These results suggest that PCDH19 plays a major role in epileptic encephalopathies, with a clinical spectrum overlapping that of DS. This disorder mainly affects females. The identification of an affected mosaic male strongly supports the hypothesis that cellular interference is the pathogenic mechanism

    Les mécanismes contractuels de protection du savoir-faire

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    Les drones face aux enjeux de propriété intellectuelle

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    Les réformes du droit des brevets prévues par le projet de loi PACTE

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    Introduction

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    Préface

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    Comme l’écrit le sociologue Georg Simmel : « L’homme est un être qui a l’étrange capacité de se passionner pour des choses qui ne concernent en rien ses intérêts. » En ce sens, nous pouvons être convaincus que s’il arrive du neuf, de l’innovation, de la nouveauté dans ce que nous vivons, c’est précisément parce que nous nous intéressons et que nous avons avec les êtres et les choses à construire, à un moment ou un autre, un rapport susceptible de dépasser véritablement, sans que nous sachions..

    Introduction

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    Objets connectés et basketball : enjeux sportifs, défis juridiques

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    Préface

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    Comme l’écrit le sociologue Georg Simmel : « L’homme est un être qui a l’étrange capacité de se passionner pour des choses qui ne concernent en rien ses intérêts. » En ce sens, nous pouvons être convaincus que s’il arrive du neuf, de l’innovation, de la nouveauté dans ce que nous vivons, c’est précisément parce que nous nous intéressons et que nous avons avec les êtres et les choses à construire, à un moment ou un autre, un rapport susceptible de dépasser véritablement, sans que nous sachions..
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