Short-acting inhaled β2-agonists: why, whom, what, how?

We showed the present data about the efficacy and safety of inhaled short-acting β2-agonists (SABA), such as salbutamol and fenoterol, in the management of obstructive diseases in children and adults. Our work discusses major mechanisms of action, clinical effects, possible side effects and indications of inhaled SABA. We presented current recommendations for the position of SABA in the therapy of obstructive diseases in children and adults, particularly in asthma and chronic obstructive pulmonary disease

Inhalatory suchego proszku — między lekarzem a pacjentem

W pracy przedstawiono pokrótce aktualnie dostępne inhalatory suchego proszku (DPI). Na podstawie danych z piśmiennictwa omówiono najczęstsze błędy popełniane przez chorych przy stosowaniu DPI oraz ich następstwa kliniczne i ekonomiczne. Szeroko omówiono czynniki wpływające na skuteczność i bezpieczeństwo terapii inhalacyjnej astmy i przewlekłej obturacyjnej choroby płuc (POChP), w tym głównie z DPI. Wskazano możliwości poprawy efektywności terapii inhalacyjnej z perspektywy lekarza oraz chorego na astmę lub POChP. Przedstawiono algorytm wyboru DPI uwzględniający preferencje i kompetencje chorego.W pracy przedstawiono pokrótce aktualnie dostępne inhalatory suchego proszku (DPI). Na podstawie danych z piśmiennictwa omówiono najczęstsze błędy popełniane przez chorych przy stosowaniu DPI oraz ich następstwa kliniczne i ekonomiczne. Szeroko omówiono czynniki wpływające na skuteczność i bezpieczeństwo terapii inhalacyjnej astmy i przewlekłej obturacyjnej choroby płuc (POChP), w tym głównie z DPI. Wskazano możliwości poprawy efektywności terapii inhalacyjnej z perspektywy lekarza oraz chorego na astmę lub POChP. Przedstawiono algorytm wyboru DPI uwzględniający preferencje i kompetencje chorego

A case report of allergic bronchopulmonary aspergillosis - disease well known but rarely diagnosed

Allergic bronchopulmonary aspergillosis (ABPA) is a consequence of hypersensitivity reaction to Aspergillus fumigatus that can chronically colonize the air ways of patients with abnormalities in their airway mucosal defenses, including mucociliary clearance and epithelial cell function, such as patients with bronchial asthma and cystic fibrosis. We present an interesting case of a 62-year-old woman who presented with purulent cough, subfebrile temperature and chest pain. She was ineffectively treated for a month with standard antibiotics and was finally diagnosed with ABPA

Hiccup as an uncommon symptom of pneumonia

Terlecka Paulina, Grzywa Celińska Anna, Emeryk Maksymiuk Justyna, Szmygin Milanowska Katarzyna, Milanowski Janusz. Hiccup as an uncommon symptom of pneumonia. Journal of Education, Health and Sport. 2017;7(12):111-117. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1108599 http://ojs.ukw.edu.pl/index.php/johs/article/view/5108 https://pbn.nauka.gov.pl/sedno-webapp/works/840705 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.11.2017. Revised: 15.11.2017. Accepted: 12.12.2017. Hiccup as an uncommon symptom of pneumonia Paulina Terlecka1, Anna Grzywa-Celińska1, Justyna Emeryk-Maksymiuk2, Katarzyna Szmygin-Milanowska1, Janusz Milanowski1 1 - Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Poland 2 - Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of Lublin, Poland Corresponding author: Paulina Terlecka, MD Chair and Department of Pneumonology, Oncology and Allergology Medical University of Lublin 20-954 Lublin, Poland 8 Jaczewskiego St. phone number: +48817244431 fax number: +48817244823 e-mail: [email protected] Abstract Hiccup is a symptom resulting with uncontrolled contractions of the diaphragm and external intercostals muscles with inspiration and with simultaneous sudden closure of the glottis, that produces specific “hic” sound. Depending on the time of duration, hiccup can be classified as acute (up to 48h), chronic (48h to 1 month) and persistent (lasting longer than one month). The exact pathophysiology of this symptom still remains unknown, though it is well known, that short-term episodes of hiccup are mainly caused by oesophagus and stomach diseases (gastric and duodenal ulcers, gastritis, gastro-oesophageal reflux) or alcohol consumption. Other reasons of this phenomenon include the diseases with the stimulation of the vagus nerve or conditions with diaphragm irritation. It can be also psychogenic or resulting from central nervous system diseases. Short term episodes of hiccup happen to every person and do not cause any concern. Chronic hiccups can lead to significant worsening of quality of life including fatigue, nutritional restrictions, dehydration, weight loss, insomnia, respiratory disorders, depression or even suicidal thoughts. We present an interesting case with diagnostic and therapeutic procedures in a 65-year-old smoker, who was hospitalized in our Department because of pneumonia, with persistent hiccup as an additional complaint considerably deteriorating his quality of life. Key words: hiccup, symptom, pneumonia

Malignant peripheral nerve sheath tumor in a patient without neurofibromatosis 1 (NF1): a rare case of primary lung location

We present a rare case of a patient operated due to a lung tumor, which was ultimately diagnosed as malignant peripherial nerve sheath tumor (MPNST). MPNSTs are rare tumors of soft tissue with mesenchymal origin. The World Health Organization has distinguished this group in order to unify terms in mesenchymal heterogeneous malignant tumors, e.g. neurofibrosarcomas, malignant schwannomas and malignant neurilemmoma [1]. They can occur as a result of neoplastic expansion of peripheral nerves’ branches, peripheral nerve fibers’ sheaths or Schwann cells, although many researchers believe that these tumors can derive not only from one, but several cell lines. MPNSTs are very rare in thorax, where they show aggressive pattern of growth [2] and stem from pleural cells rather than lung tissue.   

Krótko działające b2-mimetyki w inhalacji — dlaczego, dla kogo, jaki, jak?

Przedstawiono aktualne dane na temat efektywności i bezpieczeństwa krótko działających b2-mimetyków (SABA, short-acting b2-agonists), takich jak salbutamol i fenoterol, w inhalacji w terapii chorób obturacyjnych oskrzeli u dzieci i dorosłych. W pracy omówiono najważniejsze mechanizmy działania, efekty kliniczne, możliwe działania uboczne oraz wskazania związane z inhalacyjnymi postaciami SABA. Przedstawiono aktualne zalecenia dotyczące miejsca SABA w terapii chorób obturacyjnych oskrzeli u dzieci i dorosłych, w tym szczególnie w astmie i przewlekłej obturacyjnej chorobie płuc

Short-Acting Inhaled β2-Agonists: Why, Whom, What, How?

We showed the present data about the efficacy and safety of inhaled short-acting β2-agonists (SABA), such as salbutamol and fenoterol, in the management of obstructive diseases in children and adults. Our work discusses major mechanisms of action, clinical effects, possible side effects and indications of inhaled SABA. We presented current recommendations for the position of SABA in the therapy of obstructive diseases in children and adults, particularly in asthma and chronic obstructive pulmonary disease

Dry Powder Inhalers—Between the Doctor and the Patient

The article briefly presents currently accessible dry powder inhalers (DPI). Basing on the data from the literature, we discussed the most common mistakes related to the utilisation of DPI as well as their clinical and economic consequences. We also extensively analysed all factors that may influence the efficacy and safety of inhaler therapy of asthma and COPD, mostly with the use of DPI. In addition, we indicated the potential to improve the efficacy of inhaler therapy from the doctor and COPD or asthma patient perspective. We also presented a DPI choice algorithm including the patient’s preferences and competences

Hiccup as an uncommon symptom of pneumonia

Hiccup is a symptom resulting with uncontrolled contractions of the diaphragm and external intercostals muscles with inspiration and with simultaneous sudden closure of the glottis, that produces specific “hic” sound. Depending on the time of duration, hiccup can be classified as acute (up to 48h), chronic (48h to 1 month) and persistent (lasting longer than one month). The exact pathophysiology of this symptom still remains unknown, though it is well known, that short-term episodes of hiccup are mainly caused by oesophagus and stomach diseases (gastric and duodenal ulcers, gastritis, gastro-oesophageal reflux) or alcohol consumption. Other reasons of this phenomenon include the diseases with the stimulation of the vagus nerve or conditions with diaphragm irritation. It can be also psychogenic or resulting from central nervous system diseases. Short term episodes of hiccup happen to every person and do not cause any concern. Chronic hiccups can lead to significant worsening of quality of life including fatigue, nutritional restrictions, dehydration, weight loss, insomnia, respiratory disorders, depression or even suicidal thoughts.             We present an interesting case with diagnostic and therapeutic procedures in a 65-year-old smoker, who was hospitalized in our Department because of pneumonia, with persistent hiccup as an additional complaint considerably deteriorating his quality of life

The impact of education on therapy in patients with asthma

Asthma is a chronic disease that still causes a serious health, social and economic burden. Despite the growing knowledge concerning the pathomechanism of the disease and the availability of modern therapeutic possibilities, asthma is often still inadequately controlled. Unfortunately, a large group of patients do not comply with medical recommendations. The reasons for this phenomenon are many. Non-compliance and lack of control of disease are often caused by the lack of information on the side of the patients, so it is important to educate them. It is the foundation on which the awareness of the disease is built. Education of patients with asthma is also essential to improve communication and relationship between the physician, the patient and his family, which is crucial to the success of treatment