THE ROLE OF PROFESSIONAL DEVELOPMENT IN PROMOTING UNIVERSITY TEACHERS TEACHING PROFESSION – A CASE STUDY: KING KHALID UNIVERSITY TEACHERS, COLLEGE OF SCIENCE AND ARTS, KINGDOM OF SAUDI ARABIA, FORMER UNIVERSITY: SUDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY, KHARTOUM, SUDAN

The purpose of this study is to investigate to what extent professional development promotes university teachers teaching profession. The researcher used the quantitative method of the research representing in interviews with university teachers at King Khalid University who is the sample of the study. The main findings of the research: firstly; high-quality professional development provides room for teachers to think outside the box and aspires for better. Secondly, teachers will interchange ideas when they collaborate in professional development sessions. Finally, professional development helps teachers’ to be creative and innovative inside classrooms.  Article visualizations

Establishment of Structured Care Program for Children with Type 1 Diabetes in Low Income Countries: Integrated Management of Diabetes in Children (IMDC) Project in Sudan.

he Integrated Management of Diabetes in children (IMDC) is a program established to provide astructured care for children with type 1 diabetes in Gezira State, Sudan. It is a result of partnership between Faculty of Medicine –University of Gezira, World Diabetes Foundation and State Ministry of Health. This project has adopted a collaborative structure of providing care in health facilities, school and with the families. Partnership development with relevant sectors involved in diabetes care is one of the crucial strategies adopted to achieve the objectives. IMDC project develop the first management guidelines, train health personnel and teachers in schools and empower children and their families, produce  local education materials, and the establish reference laboratory and satellite clinics for diabetes care. In conclusion the care of children with diabetes needs collaboration between the health system, families and the schools. Partnership is crucial to implement programmes aiming at improving the care given to children with diabetes as each partner has a role in diabetes care continuum. Keywords: Diabete type 1, Sudan, Management, Childre

Dual targeting of carbonic anhydrase and vascular endothelial growth factor as an innovative approach in developing potential cancer-fighting candidates for the management of hypoxic malignancies

Cancer poses a global challenge, and the Middle East is not immune to its impact. According to a 2020 published study, nearly half a million new cancer cases were detected in Arab countries, which equates to approximately 100 patients per 100,000 people. Additionally, cancer is the second to third leading cause of mortality in the majority of Arab nations. Our scientific team is adamant about avoiding succumbing to this sickness. We did a thorough literature study in order to create anti-cancer molecules. We intend to use the findings and recommendations from existing research to develop new medications that will battle cancer and lessen its destructive consequences. Through an innovative and previously unexplored approach, our drug candidate design focuses on limiting cancer cell proliferation and preventing metastasis. Carbonic anhydrase (CA) and vascular endothelial growth factor (VEGF) are both targeted in this strategy. Both are required for the survival and growth of cancer cells. When cancer cells divide uncontrollably, they produce an oxygen-deficient (hypoxic) environment. To adapt to this challenge, cells activate a metabolic pathway that leads to the production of these enzymes, ensuring cancer cell survival in the face of hypoxia-induced stress. Our research team's medications have undergone comprehensive testing on a large number of cancer cells under both normal oxygen (normoxia) and hypoxic environments. Surprisingly, these drug candidates impeded cancer cell proliferation in both conditions. What's more amazing is that these medications have had no effect on healthy cells. This quality reduces the likelihood of adverse side effects when administered to patients. Furthermore, laboratory investigations and computer simulations have shown the candidates' potential to suppress the action of the examined enzymes, CA and VEGF, on cancer cells

Effect of an Educational Program on Adherence to Therapeutic Regimen among Chronic Kidney Disease Stage5 (CKD5) Patients under Maintenance Hemodialysis

The burden of chronic disease on health care services worldwide is growing and the increased development of educational interventions which help patients to better manage their conditions is evident internationally. It has been recognized that poor adherence can be a serious risk to the health and wellbeing of patients. Adherence to fluid restrictions, dietary and medication guidelines as well as attendance at prescribed hemodialysis sessions of a hemodialysis regimen are essential for adequate management of chronic kidney disease. The objective of the present study is to  investigate the effect of an educational program on adherence to therapeutic regimen among chronic kidney disease stage 5 (CKD5) patients under maintenance hemodialysis at Kasr AlAiny center for Nephrology, Dialysis and transplantation (KAC-NDT), Cairo University. To fulfill the aim of this study a purposive sample of sixty adult male and female patients on maintenance hemodialysis for at least 6 months and not more than one year were assigned. Socio-demographic and medical data sheet, laboratory investigation assessment data sheet, pre/post knowledge assessment data sheet and adherence assessment data sheet were utilized for data collection. The study results revealed, the post total mean knowledge scores of the study subjects increased significantly in follow up assessment times  as compared to the pre-program assessment (X2=  186.332, P= 0.001). The post total mean adherence scores of the study subjects is increased significantly in follow up assessment times  as compared to the pre-program assessment ( X2= 34.587 , P= 0.001).  Frequent and repeated contacts with renal nurses can help these patients develop problem-solving skills, set goals, and understand their progress in managing multiple aspects of their disease. Individualization of the common educational approach by incorporating the patient’s beliefs, behaviors, and emotional and physical feelings as well as culture, economic situation, ability and knowledge of the disease and its treatment supports self- management. Key wards: chronic kidney disease, hemodialysis, knowledge, adherence, diet and fluid restrictions

DEVELOPMENT AND REPRODUCTION OF THE TWO PREDATORY MITES EUSEIUS scutalis AND TYPHLODOROMIPS swirskii (ACARI: PHYTOSEIIDAE) AS AFFECTED BY LEAF TEXTURE OF STRAWBERRY PLANTS

The predatory phytoseiid mites Euseius scutal-is (El-Badry) and Typhlodrompis swirskii (Athias–Henriot) successfully developed and reproduced on strawberry leaves, infested with mymphs of the two-spotted spider mite Tetramychus urticae kock as prey, of both Yaeel (smooth slight hairy) and Vantana (rough dense hairy) cultivars indicating a different effect of leaf surface on their behaviour at 27o C and 70% RH.Yaeel leaf was the most appropriate surface and Vantana ones was the least. Longevity was the greatest on Yaeel (31.92 and 28.48 days) and the shortest on Vantana (19.40 and 15.50 days) for each predator, respec-tively. The total number of eggs/ female was 39.00 and 41.34 on Yaeel and 21.02 and 19.68 on Vantana, respectively. Population of the two pred-ators multiply 29.21 and 27.41 in a generation time of 15.78 and 13.93 days on Yaeel, whilst they were (Ro= 14.77 and 14.79) and (T= 14.26 and 12.55 days)on Vantana, respectively. Life table parameters also indicated that the smooth Yaeel leaves are better host-plants for predators in terms rm and erm. Trichomes characteristics on midrib and blade of Yaeel and Vantana strawberry leaves were determine

Thymoquinone ameliorates acrylamide-induced reproductive toxicity in female rats: An experimental study

Background: Acrylamide (AA) is a carcinogenic compound that causes severe reproductive impairments and represents a high environmental risk factor. Thymoquinone (TQ) has a unique antioxidant activity and has been widely used as a protective agent against various types of toxicity. Objective: To evaluate the protective effects of TQ against AA-induced reproductive toxicity in female rats. Materials and Methods: In this experimental study, 40 female albino rats (120-150 gr, 8-10 wk) were sorted into 4 groups, (n = 10/each), vehicle group (received a daily oral administration of 0.5 ml saline [9%]); AA group (received a daily oral administration with freshly prepared AA, 20 mg/kg body weight) for 21 days which is less than the lethal dose LD50 of AA in rats (20 mg/kg body weight); AA+TQ group (received a daily oral administration of TQ, 10 mg/kg body weight) after AA intoxication for 21 days, and TQ group (received a daily oral administration of TQ only, 10 mg/kg body weight) for 21 consecutive days. Reproductive hormones, carcinogenic biomarkers, and oxidative stress markers were measured. The histological assessment showed the protective effect of TQ against AA-induced ovarian injury. Network pharmacology analysis and molecular docking approach were carried out to determine the binding affinity of TQ with cyclooxygenase 2. Results: TQ administration significantly enhanced the functional capacity of the ovary at hormones, oxidative biomarkers, and tumor markers at a significant level of p < 0.001. Besides, TQ protects the ovary of AA-treated rats from the severe degeneration effect. Conclusion: TQ showed a promising protective effect against AA-induced reproductive toxicity in female rats. Key words: Acrylamide, Thymoquinone, Rats, Oxidative stress, Cyclooxygenase 2, Inflammation

Assessment of the Secondary Metabolite Patulin and Lycium Barbarum Fruit on INS-1 Rat Pancreatic Β-Cells

Patulin has been shown to have diabetogenic effects in mice. The effects on pancreatic β-cell viability and function of secondary metabolite patulin were investigated. Using forty adult albino male rats which divided into 4 groups. Control group was injected subcutaneously daily with distilled water for one week; group I was injected subcutaneously daily with Patulin (0.2 mg/kg/day) for two weeks. Group II was injected with the same toxin and dose for two weeks after that they were treated by Goji extract (2 ml/kg /day.) for two weeks. Group III was treated by Goji for two weeks after that they were injected with patulin for two weeks. Some biochemical parameters of blood samples for experimental rodents were evaluated. Patulin group shows significant increase in amylase and glucose levels. But level of C-peptide and Insulin decreased significantly in this group. However, there is no significant alteration in Lipase level between patulin group and control. Groups treated with goji extract in groups two and three (therapeutic and prophylactic) illustrated non significant alteration in biochemical parameters compared to control

Introducing the open source metamodel concept

The Model Driven Architecture (MDA) is a model centric software engineering methodology that aiming to enhance software productivity, reusability, maintainability and quality by focusing on models and metamodels in place of conventional code. By adopting the separation of concern these models defined in different levels of abstraction where each model syntactically conforms to a particular metamodel. Under the MDA context this work presents a novel approach for representing models and metamodels. Benefiting from the knowledge representation capability and the open structure of the Entity Attribute Value (EAV) model, we represent metamodels and its instance models in a single EAV designed repository in to support of model transformations and introducing a new concept of what we call it an Open Source Metamodel. Also this work demonstrate an integration between UML static and behavioral model

Impact of Exercise Program on Functional Status among Post- Lumbar Laminectomy Patients

A laminectomy is a surgical incision performed to remove herniated intervertebral discs. Strengthening and stretching exercise program helps post-laminectomy patients to move and do routine activities without putting extra strain on their backs, relieve their pain leading to improvement of functional status.  Aim: to evaluate the impact of exercise program on functional status among post-lumbar laminectomy patients’. Design; quasi-experimental design. Setting: This study was conducted at the neurosurgery department of El-Manial University Hospital, Cairo. Sample: A purposive sample of 30 male and female adult patients undergoing lumbar laminectomy was recruited in this study. Tools: data were collected utilizing the following tools: 1) The Structured Interview Questionnaire, including socio-demographic and related medical data. 2) Physical Assessment Sheet, and 3) Oswestry Low Back Pain Disability Questionnaire. Results: the study findings revealed that the majority of study subjects were males, married and have normal musculoskeletal posture. All participants had severe low back pain and high level of functional disabilities preoperatively. A significant difference in pain intensity and functional ability was evident between the preoperative period and six weeks postoperatively after implementing the exercise program.   Recommendations; A written hospital clinical guideline on the common causes and safe post-laminectomy exercises is recommended to be established.  Replication of this study on a larger sample and in different hospital settings with increasing the duration of implementing the postoperative exercise program treatment. Keywords: exercise program, functional status, lumbar laminectom

Effect of Healthy Lifestyle Interventions in Schools of Jazan City, Kingdom of Saudi Arabia: A Quasi-experimental Study

Background Unhealthy dietary habits and lifestyle among adolescents is considered as a risk factor for nutrition-related diseases in adulthood. The objective of this study was to investigate the effectiveness of a healthy lifestyle intervention—including physical activity (PA) and eating habits (EH)—among female students in Jizan City, southwest Kingdom of Saudi Arabia (KSA). Methods A representative sample of 565 school students aged 12–15 years was randomly selected from four schools in Jizan, KSA. The PA and EH were assessed using a validated self-administered questionnaire. A pre-post quasi-experimental study was implemented in three phases. Results Following the intervention, the school children in the intervention groups showed a significant improvement in their EH and PA. These improvements were documented in increased physical walking measured by the number of students walking daily, the number of days walked, and the time spent on vigorous activities (54.11 ± 54.89 to 63.24 ± 76.16). Fruits and vegetables had a similar consumption frequency in both the intervention and control groups. The snacks were frequently consumed among intervention group with a significant increase in the mean number from 1.64 ± 0.93 to 1.96 ± 1.13 (p = 0.000) and fast food were less frequently consumed among intervention group than the control group (p = 0.000). The prevalence of obesity in the intervention group was reduced from 16.3% to 12.9%, while it was significantly increased from 17.6% to 19.0% in the control group (p = 0.0148). Weight decreased by 0.37 kg in the intervention group, while it increased by 0.07 kg in the control group, but with no statistically significant increase. Conclusion: In conclusion, healthy lifestyle interventions can improve short- and long-term outcomes in school children. When examining the health benefits of healthy lifestyle, the importance of dietary and PA behaviors should be considered. Keywords:  lifestyle, dietary habits, physical activity, chronic diseases, Jazan-KSA &nbsp