De-biased Populations of Kuiper Belt Objects from the Deep Ecliptic Survey

The Deep Ecliptic Survey (DES) discovered hundreds of Kuiper Belt objects from 1998-2005. Follow-up observations yielded 304 objects with good dynamical classifications (Classical, Scattered, Centaur, or 16 mean-motion resonances with Neptune). The DES search fields are well documented, enabling us to calculate the probability of detecting objects with particular orbital parameters and absolute magnitudes at a randomized point in each orbit. Grouping objects together by dynamical class leads, we estimate the orbital element distributions (a, e, i) for the largest three classes (Classical, 3:2, and Scattered) using maximum likelihood. Using H-magnitude as a proxy for the object size, we fit a power law to the number of objects for 8 classes with at least 5 detected members (246 objects). The best Classical slope is alpha=1.02+/-0.01 (observed from 5<=H<=7.2). Six dynamical classes (Scattered plus 5 resonances) are consistent in slope with the Classicals, though the absolute number of objects is scaled. The exception to the power law relation are the Centaurs (non-resonant with perihelia closer than Neptune, and thus detectable at smaller sizes), with alpha=0.42+/-0.02 (7.5<H<11). This is consistent with a knee in the H-distribution around H=7.2 as reported elsewhere (Bernstein et al. 2004, Fraser et al. 2014). Based on the Classical-derived magnitude distribution, the total number of objects (H<=7) in each class are: Classical (2100+/-300 objects), Scattered (2800+/-400), 3:2 (570+/-80), 2:1 (400+/-50), 5:2 (270+/-40), 7:4 (69+/-9), 5:3 (60+/-8). The independent estimate for the number of Centaurs in the same H range is 13+/-5. If instead all objects are divided by inclination into "Hot" and "Cold" populations, following Fraser et al. (2014), we find that alphaHot=0.90+/-0.02, while alphaCold=1.32+/-0.02, in good agreement with that work.Comment: 26 pages emulateapj, 6 figures, 5 tables, accepted by A

Coronal radiation belts

The magnetic field of the solar corona has a large-scale dipole character, which maps into the bipolar field in the solar wind. Using standard representations of the coronal field, we show that high-energy ions can be trapped stably in these large-scale closed fields. The drift shells that describe the conservation of the third adiabatic invariant may have complicated geometries. Particles trapped in these zones would resemble the Van Allen Belts and could have detectable consequences. We discuss potential sources of trapped particles

A systematic review of Gamma-aminobutyric Acid Receptor Type B autoimmunity

Objective. To review the available research to describe the clinical characteristics and neoplastic associations of patients with gamma-aminobutyric acid receptor type B (GABAB-R) autoantibodies. Methods. Literature was reviewed on PubMed, Mendeley literature search, and the American Academy of Neurology database for articles published from June 2008 to October of 2018 using a variety of key words. These key words include: „gamma-aminobutyric acid seizures,” „gamma-aminobutyric acid limbic encephalitis”, „GABA(B) receptor antibodies,” „autoimmune encephalitis,” „autoimmune epilepsy,” „GABA(B) encephalitis, „ and “GABA paraneoplastic.” With the results, the papers were reviewed in a systematic manner. Results. A total of 10 studies were reviewed. A summary of the demographic, clinical, and serological findings of the cases detailed in the literature are provided. An additional illustrative case is described. In total, 94 patients were reviewed. Conclusions. GABAB-R autoimmune disease is characterized by refractory seizures or status epilepticus and frequent association with small cell lung cancer. Additionally, a substantial minority of patients have non-inflammatory CSF.

Judaic Journeys at the University of Michigan: from Belser to Frankel to Hermelin

Judaic studies represnts a very wife range of subject disciplines including philosophy, religion, history, folklore, political science, law, education, music, art and architecture, languages and literature, medicine, and many others. "Judaic Journeys" explores the information resources collected to support this field since the University of Michigan's founding in 1817.http://deepblue.lib.umich.edu/bitstream/2027.42/120257/1/judaic_journeys_00.pd

An X-Ray Study of the Supernova Remnant G290.1-0.8

G290.1-0.8 (MSH 11-61A) is a supernova remnant (SNR) whose X-ray morphology is centrally bright. However, unlike the class of X-ray composite SNRs whose centers are dominated by nonthermal emission, presumably driven by a central pulsar, we show that the X-ray emission from G290.1-0.8 is thermal in nature, placing the remnant in an emerging class which includes such remnants as W44, W28, 3C391, and others. The evolutionary sequence which leads to such X-ray properties is not well understood. Here we investigate two scenarios for such emission: evolution in a cloudy interstellar medium, and early-stage evolution of a remnant into the radiative phase, including the effects of thermal conduction. We construct models for these scenarios in an attempt to reproduce the observed center-filled X-ray properties of G290.1-0.8, and we derive the associated age, energy, and ambient density conditions implied by the models. We find that for reasonable values of the explosion energy, the remnant age is of order (1 - 2) x 10^{4} yr. This places a fairly strong constraint on any association between G290.1-0.8 and PSR J1105-610, which would require an anomalously large velocity for the pulsar.Comment: 7 pages, 7 figures, ApJ, accepte

Systematic and Causal Corrections to the Coherent Potential Approximation

The Dynamical Cluster Approximation (DCA) is modified to include disorder. The DCA incorporates non-local corrections to local approximations such as the Coherent Potential Approximation (CPA) by mapping the lattice problem with disorder, and in the thermodynamic limit, to a self-consistently embedded finite-sized cluster problem. It satisfies all of the characteristics of a successful cluster approximation. It is causal, preserves the point-group and translational symmetry of the original lattice, recovers the CPA when the cluster size equals one, and becomes exact as $N_c\to\infty$. We use the DCA to study the Anderson model with binary diagonal disorder. It restores sharp features and band tailing in the density of states which reflect correlations in the local environment of each site. While the DCA does not describe the localization transition, it does describe precursor effects of localization.Comment: 11 pages, LaTeX, and 11 PS figures, to appear in Phys. Rev. B. Revised version with typos corrected and references adde

Surgical management of giant Brunner's gland hamartoma: case report and literature review

Brunner's gland hamartomas (BGH) are uncommon benign tumors of the duodenum forming mature Brunner's glands. We report here an unusual case of a giant BGH that was not amenable to endoscopic or surgical local resection thus requiring a pancreaticoduodenectomy for extirpation. The relevant literature is discussed

Amplitude Modulation and Relaxation-Oscillation of Counterpropagating Rolls within a Broken-Symmetry Laser-Induced Electroconvection Strip

We report a liquid-crystal pattern-formation experiment in which we break the lateral (translational) symmetry of a nematic medium with a laser-induced thermal gradient. The work is motivated by an improved measurement (reported here) of the temperature dependence of the electroconvection threshold voltage in planar-nematic 4-methoxybenzylidene-4-butylaniline (MBBA). In contrast with other broken-symmetry-pattern studies that report a uniform drift, we observe a strip of counterpropagating rolls that collide at a sink point, and a strong temporally periodic amplitude modulation within a width of 3-4 rolls about the sink point. The time dependence of the amplitude at a fixed position is periodic but displays a nonsinusoidal relaxation-oscillation profile. After reporting experimental results based on spacetime contours and wavenumber profiles, along with a measurement of the change in the drift frequency with applied voltage at a fixed control parameter, we propose some potential guidelines for a theoretical model based on saddle-point solutions for Eckhaus-unstable states and coupled complex Ginzburg-Landau equations. Published in PRE 73, 036317 (2006).Comment: Published in Physical Review E in March 200

A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor

Morphological changes leading to aerial mycelium formation and sporulation in the mycelial bacterium Streptomyces coelicolor rely on establishing distinct patterns of gene expression in separate regions of the colony. sH was identified previously as one of three paralogous sigma factors associated with stress responses in S. coelicolor. Here, we show that sigH and the upstream gene prsH (encoding a putative antisigma factor of sH) form an operon transcribed from two developmentally regulated promoters, sigHp1 and sigHp2. While sigHp1 activity is confined to the early phase of growth, transcription of sigHp2 is dramatically induced at the time of aerial hyphae formation. Localization of sigHp2 activity using a transcriptional fusion to the green fluorescent protein reporter gene (sigHp2–egfp) showed that sigHp2 transcription is spatially restricted to sporulating aerial hyphae in wild-type S. coelicolor. However, analysis of mutants unable to form aerial hyphae (bld mutants) showed that sigHp2 transcription and sH protein levels are dramatically upregulated in a bldD mutant, and that the sigHp2–egfp fusion was expressed ectopically in the substrate mycelium in the bldD background. Finally, a protein possessing sigHp2 promoter-binding activity was purified to homogeneity from crude mycelial extracts of S. coelicolor and shown to be BldD. The BldD binding site in the sigHp2 promoter was defined by DNase I footprinting. These data show that expression of sH is subject to temporal and spatial regulation during colony development, that this tissue-specific regulation is mediated directly by the developmental transcription factor BldD and suggest that stress and developmental programmes may be intimately connected in Streptomyces morphogenesis