Medienpädagogik in Hamburg seit 1945 - Ihre exemplarische Darstellung und Dokumentation in einer Datenbank

Die vorliegende Arbeit beschäftigt sich mit der Entwicklung der Medienpädagogik in Hamburg von 1945 bis 1995. Im schriftlichen Teil der Arbeit wird untersucht, inwieweit Medien in diesem Kontext diskutiert, reflektiert und praktisch eingesetzt wurden. Der praktische Teil der Bachelorarbeit umfasst die Erstellung einer Datenbank, die einen elektronischen Zugriff auf die Untersuchungsergebnisse ermöglicht. Nachdem die Bedeutung der Medienkompetenz für das moderne Leben, herausgestellt wird, folgt Teil I mit einer theoretischen Abhandlung über die Medienpädagogik. Teil II beleuchtet die Entwicklung ausgewählter Medien in Hamburg und stellt exemplarisch innovative Medienprojekte aus der Hansestadt vor. Teil III präsentiert eine Übersicht medienpädagogisch wirkender Institutionen Hamburgs, die im Beobachtungszeitraum maßgeblich an der Förderung des kompetenten Medienumgangs beteiligt waren. Teil IV erläutert die Zielsetzung, Konzeption und Umsetzung der Datenbank. In dieser Arbeit werden Hamburger Aktivitäten im Bereich der Medienpädagogik von 1945 bis 1995 erstmalig systematisch aufbereitet

First report of changes in leukocyte morphology in response to inflammatory conditions in Asian and African elephants (Elephas maximus and Loxodonta africana).

Although the hematology of healthy elephants has been well-described, published information on hematological changes during disease is limited. The objective of this study was to describe qualitative morphological changes in the leukocytes of Asian and African elephants (Elephas maximus and Loxodonta africana) diagnosed with a variety of inflammatory conditions. Twenty-five of 27 elephants had morphological changes in their leukocytes, although only 16 of these had a concurrent inflammatory leukogram. Morphological changes included heterophil left-shifting with or without concurrent dysgranulopoiesis, toxicity, or hypersegmentation, reactive lymphocytes, plasma cells, and/or vacuolated monocytes. Although the observed leukocyte morphological changes are non-specific, their early recognition upon blood film evaluation may provide important, clinically-relevant information, particularly if the leukogram is normal. This case series is the first description of qualitative morphological changes in the leukocytes of elephants in association with inflammation

Reference intervals for acute phase protein and serum protein electrophoresis values in captive Asian elephants ( Elephas maximus

Acute phase protein (APP) immunoassays and serum protein electrophoresis (SPEP) are assays for evaluating the inflammatory response and have use as diagnostic tools in a variety of species. Acute phase proteins are markers of inflammation that are highly conserved across different species while SPEP separates and quantifies serum protein fractions based on their physical properties. In the current study, serum samples from 35 clinically healthy Asian elephants (Elephas maximus) were analyzed using automated assays for C-reactive protein, serum amyloid A, and haptoglobin and SPEP. Robust methods were used to generate reference intervals for the APPs: C-reactive protein (1.3-12.8 mg/l), serum amyloid A (0-47.5 mg/l), and haptoglobin (0-1.10 mg/ml). In addition, SPEP was performed on these samples to establish reference intervals for each protein fraction. A combination of APPs and SPEP measurements are valuable adjunctive diagnostic tools in elephant health care

Heterophil left-shifting and variably toxicity in an Asian elephant with gastrointestinal disease for demonstration of the size variation from concurrent secondary dysgranulopoiesis (giant cells).

<p>X100 objective. Wright Giemsa stain.</p

Heterophil left-shifting and variable toxicity in elephant blood films.

<p>1–6: Mature heterophils, 7–12: band heterophils, 13–20: heterophilic metamyelocytes, 21–25: heterophilic myelocytes. Grading of toxicity on a scale of 1+ (Doehle bodies, slight basophilia), 2+ (Doehle bodies, moderate basophilia), and 3+ (cytoplasmic foaminess (dark blue cytoplasm, Doehle bodies may or may not be visible) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0185277#pone.0185277.ref004" target="_blank">4</a>]. 1+ toxicity is present in 1, 7; 2+ toxicity is present in 2, 3, 8, 10, 13–15, 17–19, 22–24; 3+ toxicity is present in 4–6, 9, 11–12, 16, 20–21, 25. X100 objective. Wright Giemsa stain.</p

Abnormal morphology of elephant leukocytes.

<p>Legend: 1–2: Band heterophils, 3: heterophilic myelocyte, 4–6: hypersegmented heterophils, 7–16: reactive lymphocytes, 17: plasma cell, 18–25: activated monocytes with variable vacuolation. X100 objective. Wright Giemsa stain.</p

Normal morphology of elephant leukocytes.

<p>1: Mature heterophil, 2: Mature heterophil with Barr body in a female elephant (sex chromatin lobe), 3–4: eosinophils, 5–6: basophils, 7–8: small lymphocytes, 9: monocyte, 10–20: unique monocyte type of elephants with various stages of segmentation; note that less segmented monocytes may be misidentified as lymphocytes. 21–25: degenerative changes in leukocytes in blood films prepared 24 hr after collection, including 21: heterophil with nuclear and cytoplasmic swelling, 22: monocyte with swollen nucleus, 23–25: karyorrhexis and pyknosis in leukocytes. X100 objective. Wright Giemsa stain.</p

Overview of qualitative leukocyte morphological changes observed in blood films at initial sampling from 27 elephants with inflammatory conditions.

<p>Overview of qualitative leukocyte morphological changes observed in blood films at initial sampling from 27 elephants with inflammatory conditions.</p