9,490 research outputs found

    Teaching Digital Humanities through a Community-Centered, Team-Based Pedagogy

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    Through a focus on the Digital Humanities Practicum course at the University of Nebraska-Lincoln (UNL), this paper explores two areas of current--and recurrent--interest in digital humanities teaching and learning: DH pedagogy in the undergraduate classroom and DH and skills training. While the presentation emphasizes particulars of the course, including its design, what has worked well, and what we are still learning, we also want to think beyond the single course and prompt further discussion around several themes, including team-based problem-solving and connecting digital humanities with community-engaged learning. Ultimately, we argue that a team-based, community-engaged approach can be an effective strategy for teaching digital humanities practice to students. Furthermore, we believe that this approach can powerfully illustrate the societal benefit of humanities-centered approaches to problem-solving. Students in the Digital Humanities Practicum course get an opportunity to work together creatively, analyze a problem and conceive a solution, build something, and have a positive impact on their community

    Teaching Digital Humanities through a Community-Centered, Team-Based Pedagogy

    Get PDF
    Through a focus on the Digital Humanities Practicum course at the University of Nebraska-Lincoln (UNL), this paper explores two areas of current--and recurrent--interest in digital humanities teaching and learning: DH pedagogy in the undergraduate classroom and DH and skills training. While the presentation emphasizes particulars of the course, including its design, what has worked well, and what we are still learning, we also want to think beyond the single course and prompt further discussion around several themes, including team-based problem-solving and connecting digital humanities with community-engaged learning. Ultimately, we argue that a team-based, community-engaged approach can be an effective strategy for teaching digital humanities practice to students. Furthermore, we believe that this approach can powerfully illustrate the societal benefit of humanities-centered approaches to problem-solving. Students in the Digital Humanities Practicum course get an opportunity to work together creatively, analyze a problem and conceive a solution, build something, and have a positive impact on their community

    Self-interacting Dark Matter and Invisibly Decaying Higgs

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    Self-interacting dark matter has been suggested in order to overcome the difficulties of the Cold Dark Matter model on galactic scales. We argue that a scalar gauge singlet coupled to the Higgs boson, which could lead to an invisibly decaying Higgs, is an interesting candidate for this self-interacting dark matter particle. We also present estimates on the abundance of these particles today as well as consequences to non-Newtonian forces.Comment: 4 pages, Revte

    Genome sequence of canine herpesvirus

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    Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United Kingdom between 1985 and 2000. The sequences are very closely related to each other. The canine herpesvirus genome is estimated to be 125 kbp in size and consists of a unique long sequence (97.5 kbp) and a unique short sequence (7.7 kbp) that are each flanked by terminal and internal inverted repeats (38 bp and 10.0 kbp, respectively). The overall nucleotide composition is 31.6% G+C, which is the lowest among the completely sequenced alphaherpesviruses. The genome contains 76 open reading frames predicted to encode functional proteins, all of which have counterparts in other alphaherpesviruses. The availability of the sequences will facilitate future research on the diagnosis and treatment of canine herpesvirus-associated disease

    Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris

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    The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive to the disinfectant chlorhexidine in vitro

    Evaluation of In-Hospital Management for Febrile Illness\ud in Northern Tanzania before and after 2010 World Health\ud Organization Guidelines for the Treatment of Malaria

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    In 2010, the World Health Organization (WHO) published updated guidelines emphasizing and expanding recommendations for a parasitological confirmation of malaria before treating with antimalarials. This study aimed to assess differences in historic (2007–2008) (cohort 1) and recent (2011–2012) (cohort 2) hospital cohorts in the diagnosis and treatment of febrile illness in a low malaria prevalence area of northern Tanzania. We analyzed data from two prospective cohort studies that enrolled febrile adolescents and adults aged $13 years. All patients received quality-controlled aerobic blood cultures and malaria smears. We compared patients’ discharge diagnoses, treatments, and outcomes to assess changes in the treatment of malaria and bacterial infections. In total, 595 febrile inpatients were enrolled from two referral hospitals in Moshi, Tanzania. Laboratory-confirmed malaria was detected in 13 (3.2%) of 402 patients in cohort 1 and 1 (0.5%) of 193 patients in cohort 2 (p = 0.041). Antimalarials were prescribed to 201 (51.7%) of 389 smear-negative patients in cohort 1 and 97 (50.5%) of 192 smearnegative patients in cohort 2 (p = 0.794). Bacteremia was diagnosed from standard blood culture in 58 (14.5%) of 401 patients in cohort 1 compared to 18 (9.5%) of 190 patients in cohort 2 (p = 0.091). In cohort 1, 40 (69.0%) of 58 patients with a positive blood culture received antibacterials compared to 16 (88.9%) of 18 patients in cohort 2 (p = 0.094). In cohort 1, 43 (10.8%) of the 399 patients with known outcomes died during hospitalization compared with 12 (6.2%) deaths among 193 patients in cohort 2 (p = 0.073). In a setting of low malaria transmission, a high proportion of smear-negative patients were diagnosed with malaria and treated with antimalarials despite updated WHO guidelines on malaria treatment. Improved laboratory diagnostics for non-malaria febrile illness might help to curb this practice.\u
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