131 research outputs found
Transaction Costs, Liquidity and Expected Returns at the Berlin Stock Exchange, 1892-1913
Tension stimulation drives tissue formation in scaffold-free systems
Scaffold-free systems have emerged as viable approaches for engineering load-bearing tissues. However, the tensile properties of engineered tissues have remained far below the values for native tissue. Here, by using self-assembled articular cartilage as a model to examine the effects of intermittent and continuous tension stimulation on tissue formation, we show that the application of tension alone, or in combination with matrix remodelling and synthesis agents, leads to neocartilage with tensile properties approaching those of native tissue. Implantation of tension-stimulated tissues results in neotissues that are morphologically reminiscent of native cartilage. We also show that tension stimulation can be translated to a human cell source to generate anisotropic human neocartilage with enhanced tensile properties. Tension stimulation, which results in nearly sixfold improvements in tensile properties over unstimulated controls, may allow the engineering of mechanically robust biological replacements of native tissue
International equity portfolio investment and enforcement of insider trading laws: a cross-country analysis
In this study, we examine the effects of stringent insider trading laws’ enforcement, institutions and stock market development on international equity portfolio allocation using data from 44 countries over the period 2001-2015. Our results suggest that stringent insider trading laws and their enforcement exert a positive and significant impact on international portfolio investment allocation. Further analysis indicates that the interaction between a country’s institutional quality, stock market development and enforcement of insider trading laws have a positive and significant effect on international equity portfolio allocation. The findings of this study have implications for the design of portfolio investment trading strategies and contribute to the literature on foreign equity investment decisions
177 Low T on Social Media: Using a Big Data Approach to Understand Patients' Anxieties about Hypogonadism and Testosterone Replacement Therapy
156 Intralesional Collagenase Clostridium Histolyticum Therapy for Peyronie's Disease is Safe in Patients Continuing Antiplatelet and Anticoagulant Therapy: A Single Center Experience
001 Taking Matters Into Their Own Hands: Men Seeking Pornography Addiction Advice From a Nontraditional Online Therapy Source
154 Continued Improvement After More than Eight Injections of Collagenase Clostridium Histolyticum for Peyronie's Disease
118 Rates of Completion and Reasons for Dropout from a Standard Eight-Injection Course of Collagenase Clostridium Histolyticum Therapy
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