Long term chemoradiotherapy-related dental and skeletal complications in a young female with nasopharyngeal carcinoma

We describe the long-term complications six years after chemoradiotherapy in a 20-year old woman with nasopharyngeal carcinoma. We wanted to know whether the radiation dose was constant throughout the oral cavity, and thus uniformly affecting the corresponding dental and skeletal structures. Clinical and radiologic findings are described six years after chemoradiotherapy based on a two-dimensional computerized treatment planning system. This revealed radiation caries limited only to posterior teeth, proximal caries in the anterior teeth, limited but continuous salivary flow, mild periodontal infection, mild xerostomia, and a regenerative capacity of bones and the developmental process. The quantitative assessment of radiation delivered to the mandible revealed a high radiation dose in the posterior area and a minimal dose in the anterior area. This explains the differences in caries manifestation between the anterior and posterior teeth. According to the present study, individualized radiation fields, using a two-dimensional treatment planning system, result in restriction of severe damage of the dental and skeletal structures, which usually follows chemoradiotherapy. Orthodontic treatment could be initiated according to individual patient needs

Ground-based aerosol optical depth trends at three high-altitude sites in Switzerland and Southern Germany from 1995–2010

Ground-based aerosol optical depth (AOD) climatologies at three high-altitude sites in Switzerland (Jungfraujoch and Davos) and Southern Germany (Hohenpeissenberg) are updated and re-calibrated for the period 1995 – 2010. In addition, AOD time-series are augmented with previously unreported data, and are homogenized for the first time. Trend analysis revealed weak AOD trends (λ = 500 nm) at Jungfraujoch (JFJ; +0.007 decade-1), Davos (DAV; +0.002 decade-1) and Hohenpeissenberg (HPB; -0.011 decade-1) where the JFJ and HPB trends were statistically significant at the 95% and 90% confidence levels. However, a linear trend for the JFJ 1995 – 2005 period was found to be more appropriate than for 1995 – 2010 due to the influence of stratospheric AOD which gave a trend -0.003 decade-1 (significant at 95% level). When correcting for a recently available stratospheric AOD time-series, accounting for Pinatubo (1991) and more recent volcanic eruptions, the 1995 – 2010 AOD trends decreased slightly at DAV and HPB but remained weak at +0.000 decade-1 and -0.013 decade-1 (significant at 95% level). The JFJ 1995 – 2005 AOD time-series similarly decreased to -0.003 decade-1 (significant at 95% level). We conclude that despite a more detailed re40 analysis of these three time-series, which have been extended by five years to the end of 2010, a significant decrease in AOD at these three high-altitude sites has still not been observed

CAST constraints on the axion-electron coupling

In non-hadronic axion models, which have a tree-level axion-electron interaction, the Sun produces a strong axion flux by bremsstrahlung, Compton scattering, and axiorecombination, the "BCA processes." Based on a new calculation of this flux, including for the first time axio-recombination, we derive limits on the axion-electron Yukawa coupling gae and axion-photon interaction strength ga using the CAST phase-I data (vacuum phase). For ma <~ 10 meV/c2 we find ga gae < 8.1 × 10−23 GeV−1 at 95% CL. We stress that a next-generation axion helioscope such as the proposed IAXO could push this sensitivity into a range beyond stellar energy-loss limits and test the hypothesis that white-dwarf cooling is dominated by axion emission

POSITRON ANNIHILATION STUDIES IN IONIC CRYSTALS

POSITRON ANNIHILATION IN IONIC CRYSTALS IS STUDIED. POSITRON LIFETIME, DOPPLER BROADENING AND 3-Γ ANNIHILATION TECHNIQUES WERE USED. THE THEORETICAL BACKGROUND THE STATE OF THE ART OF THE TECHNIQUES USED AND SOME IMPORTANT POINTS ON POSITRON ANNIHILATION RESEARCH IN IONIC CRYSTALS ARE GIVEN. THE PURPOSE OF THIS THESIS WAS TO SHED MORE LIGHT TO THE COMPLICATED ANNIHILATION MECHANISMS IN IONIC CRYSTALS. A STRONG TEMPERATURE ANNIHILATION MECHANISMS IN IONIC CRYSTALS. A STRONG TEMPERATURE WAS REVEALED IN BAF2 IN THE RANGE BETWEEN 12K AND 292K. A RELATION WAS FOUND BETWEEN THE FRACTIONS OF POSITRONIUM AS THEY ARE GIVEN BY LIFETIME MEASUREMENTS, ANGULAR CORRELATION MEASUREMENTS AND 3-Γ ANNIHILATION MEASUREMENTS.Η ΠΕΡΙ ΗΣ Ο ΛΟΓΟΣ ΔΙΑΤΡΙΒΗ ΕΙΝΑΙ ΜΕΛΕΤΗ ΤΗΣ ΕΞΑΥΛΩΣΗΣ ΤΟΥ ΠΟΖΙΤΡΟΝΙΟΥ ΣΕ ΙΟΝΤΙΚΑ ΥΛΙΚΑ, ΜΕ ΧΡΗΣΗ ΤΩΝ ΤΕΧΝΙΚΩΝ ΧΡΟΝΙΣΜΟΥ, ΔΙΑΠΛΑΤΥΝΣΗΣ DOPPLER ΚΑΙ 3-Γ ΕΞΑΥΛΩΣΗΣ. ΣΤΗΝ ΔΙΑΤΡΙΒΗ ΠΑΡΟΥΣΙΑΖΟΝΤΑΙ, ΕΝ ΠΡΩΤΟΙΣ, ΤΟ ΘΕΩΡΗΤΙΚΟ ΥΠΟΒΑΘΡΟ ΚΑΙ Η ΤΕΧΝΙΚΗ ΠΟΥ ΧΡΗΣΙΜΟΠΟΙΕΙΤΑΙ ΣΤΗ ΜΕΛΕΤΗ ΤΗΣ ΕΞΑΥΛΩΣΗΣ ΠΟΖΙΤΡΟΝΙΟΥ ΣΤΗΝ ΥΛΗ ΚΑΙ ΤΟ ΜΕΧΡΙ ΣΤΙΓΜΗΣ ΙΣΤΟΡΙΚΟ ΤΗΣ ΕΞΑΥΛΩΣΗΣ ΠΟΖΙΤΡΟΝΙΩΝ ΣΤΟΥΣ ΙΟΝΤΙΚΟΥΣ ΚΡΥΣΤΑΛΛΟΥΣ. ΣΤΟΧΟΣ ΤΗΣ ΔΙΑΤΡΙΒΗΣ ΗΤΑΝ Η ΣΥΜΒΟΛΗ ΣΤΗΝ ΔΙΑΛΕΥΚΑΝΣΗ ΤΩΝ ΕΝ ΓΕΝΕΙ ΙΔΙΑΙΤΕΡΑ ΠΟΛΥΠΛΟΚΩΝ ΜΗΧΑΝΙΣΜΩΝ ΕΞΑΥΛΩΣΗΣ ΣΕ ΙΟΝΤΙΚΑ ΥΛΙΚΑ. ΑΝΑΔΕΙΧΘΗΚΕ ΙΣΧΥΡΗ ΘΕΡΜΟΚΡΑΣΙΑΚΗ ΕΞΑΡΤΗΣΗ ΤΩΝ ΧΡΟΝΙΚΩΝ ΠΑΡΑΜΕΤΡΩΝ ΕΞΑΥΛΩΣΗΣ ΣΤΟ BAF2 ΣΤΗΝ ΠΕΡΙΟΧΗ ΑΠΟ 12Κ ΩΣ 292Κ. ΣΥΣΧΕΤΙΣΘΗΚΑΝ ΤΑ ΠΟΣΟΣΤΑ ΔΗΜΙΟΥΡΓΙΑΣ ΠΟΖΙΤΡΟΝΙΟΥΜ ΠΟΥ ΔΙΝΟΝΤΑΙ ΑΠΟ ΧΡΟΝΙΚΕΣ ΜΕΤΡΗΣΕΙΣ, ΜΕΤΡΗΣΕΙΣ ΓΩΝΙΑΚΗΣ ΚΑΤΑΝΟΜΗΣ ΚΑΙ 3-Γ ΕΞΑΥΛΩΣΗΣ