Management of complex skin defects on the feline distal tibia by using myocutaneous flaps

The study included 24 purpose-bred DSH cats, which were randomly allocated into two groups (A, B). In each cat two identical wounds were created on both tibial areas so as wounds of the one hindlimb were covered by myocutaneous ST flaps, whereas wounds of the contralateral hindlimb were left to heal by second intention (controls). In group A (n=12), the semitendinosus muscle as whole was used to create the myocutaneous flaps, depending on the distal vascular pedicle, whereas in group B (n=12), the split-semitendinosus muscle, after longitudinal separation of the muscle fibers, was used. In both groups clinical assessment scoring, planimetry, CTA and histological examination of the semitendinosus muscle were performed for the postoperative monitoring of the flaps.Σε 2 ομάδες (Α και Β) των 12 ζώων (γάτες φυλής Κοινής Ευρωπαϊκής) δημιουργήθηκαν στα οπίσθια άκρα των ζώων σύνθετα ελλείμματα στην εσωτερική επιφάνεια της κνήμης. Για την κάλυψη των ελλειμάτων αυτών, στην ομάδα Α, χρησιμοποιήθηκε ολόκληρος ο ημιτενοντώδης μυς ως μυοδερματικός κρημνός, ενώ, στην ομάδα Β ο μυς χρησιμοποιήθηκε μετά από επιμήκη διαχωρισμό των μυϊκών ινών του . Στα ετερόπλευρα άκρα των ζώων τα σύνθετα ελλείμματα που δημιουργήθηκαν (τραύματα μάρτυρες), επουλώθηκαν κατά δεύτερο σκοπό. Η μετεγχειρητική αξιολόγηση των κρημνών και των τραυμάτων μαρτύρων γινόταν με κλινική βαθμολογία, πλανιμετρία, υπολογιστική τομογραφική αγγειογραφία και ιστοπαθολογική εξέταση των μυών

First-Intention Incisional Wound Healing in Dogs and Cats: A Controlled Trial of Dermapliq and Manuka Honey

This study aimed to compare incisional wound healing in cats and dogs after the topical application of Μanuka honey and a new medical device, Dermapliq. Comparisons were made between each treatment and control, between the two treatments, and between dogs and cats. Twelve cats and twelve dogs were included in this study, and the impact of the two substances was examined through cosmetic, clinical, ultrasonographical, and histological evaluation. The use of Dermapliq in first-intention wound healing achieved a significantly better cosmetic evaluation score and better total clinical score at days 20–41, compared to the control, in both dogs and cats. The ultrasonographically estimated wound area was smaller with Dermapliq compared to the control. Wounds treated with Dermapliq showed histologically less inflammation compared to the control. The use of Manuka honey did not show a significantly better cosmetic score compared to the control. Skin thickening was significantly higher after using Manuka honey compared to the control and so was the total clinical score. However, the median wound area, as was evaluated ultrasonographically, was significantly smaller when wounds were treated with Manuka honey, the difference being more apparent in dogs. Dermapliq was proven to be a better choice in achieving favorable wound healing than Manuka honey in dogs and cats in first-intention healing. In our study, cats had a statistically better cosmetic score and less skin thickening and scar width compared to dogs. Histologically, cats showed significantly less edema, higher inflammation and angiogenesis scores, and lower fibroblast and epidermis thickening scores when compared to dogs

Magnetic and radio-labeled bio-hybrid scaffolds to promote and track in vivo the progress of bone regeneration

This work describes the preparation, characterization and functionalization with magnetic nanoparticles of a bone tissue-mimetic scaffold composed of collagen and hydroxyapatite obtained through a biomineralization process