20 research outputs found

    EXAMINING THE RELATIONSHIP BETWEEN EMOTIONAL COMPETENCE AND THE CHOSEN PSYCHOLOGICAL CHARACTERISTICS OF TEACHERS IN NORMAL SCHOOLS AND SPECIAL SCHOOLS

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    The present study aimed at unraveling the relationship between the trait emotional competence of teachers in normal schools and in special schools and their psychological characteristics mental health, sociability, and emotional wellbeing. The researcher adopted descriptive survey method which enabled her to design her own data collecting instrument for studying emotional competence of teachers and also to make use of suitable sampling technique for identifying the relationship between the dependent and independent variables in a scientific manner. The study has shown that mental health and sociability are the significant correlates of emotional competence of both the categories of teachers. The further analysis revealed that both the psychological correlates have emerged as the significant predictors of the trait emotional competence. The researcher has discussed the implications of the findings at length

    Phytochemical screening and antimicrobial activity of leaf extracts of Crossandra infundibuliformis (L.) nees on common bacterial and fungal pathogens

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    Abstract The medicinally active substances were isolated from leaves of Crossandra infundibuliformis by Soxhlet extractor and identified by phytochemical tests. The soxhlet extraction in powdered form was performed using aqueou

    Preclinical safety evaluation of ā€œVasanthakusumakara Mathiraiā€

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    The test drug Vasanthakusumakara Mathirai was taken from the text ā€œSiddha VaithiyaThirattuā€ for evaluation of safety.The Literature review reveals that there was no safety related research has been done in VKM. An initial Step in this study is a part of Standardization and preclinical safety evaluation of this drug was done. The test drug is prepared as per Siddha literature which is indicated for various respiratory disorders, Aiyairumal (cough due to kabadiseas), Siruneernoi (Renal disorders), Thagam(Excessive thirst), Eppam (Belching), Mookkadaippu (Nasal polyp). ā– Aim of this dissertation is to study the safety of test drug by acute, Sub acute study in animal model. The toxicity of the test drug VKM is done by universal accepted scientific methods. The study drug VKMwas obtained from IMPCOPS pharmacy, kalki Krishnamurthy salai, Thiruvanmiyur , Chennai-600041, Tamil Nadu. The preparation of trial drug was standardized primarily by physicochemical, biochemical analysis and Heavy metal analysis then evaluated safety of the drug by Acute and Sub- acute toxicity study. ā– Organoleptic Character of VKM showed it has solid state, brick red in colour, mild aromatic and soft in nature. Initially the trial drug VKM was subjected to physio - chemical analysis. The loss on drying of VKM stipulates higher stability of drug. Uniformity of weight shows average weight of VR (0.102gm) within prescribed limit. Disintegration time of VKM is within 20 minutes. It indicates tablet was easily disintegrated and its absorption would be good. Hardness of VKM revealed the tablets are withstands up to 2.3 kg of compression. Total Ash value (43.52%) indicates purity of VKM. Water soluble and alcohol soluble extractive test of VR shows 10.75% and 9.35%, it reveals quality as well as purity of drug. PH of VKM was 5.35% in 10% of solution, so the drug was weakly acidic in nature. The bio chemical analysis of VKM indicates the presence of Sulphate, silicate, carbonate, sodium, chloride, borate, lead, mercury, zinc, Aluminium, Iron and Calcium. ā– Heavy metal analysis was carried out in VKM by ICP-OES to ensure the absence of Arsenic, Mercury, Cadmium and Lead. ICP-OES result showed that the presence of 0.39 Ī¼g/g of Arsenic, BDL of Cadmium, 73.54 Ī¼g/g of Copper, 73.64 Ī¼g/g of Lead, 54 Ī¼g/g of Manganese, 1.17 (% w/w) of Mercury, and 24.16 Ī¼g/g of Zinc in VKM. Results showed heavy metals in the test drug are present in allowed level. ā– The acute toxicity study shows that VKM does not produce any toxic effect at the dose up to 2000 mg/kg within 24 hours in Wistar albino rats. Body weight, feed intake and water intake is normal during the treatment period. No mortality and pathological changes have been noted in the internal organs of both control and treated group on the 15th day of the study. ā– In Repeated dose 28 days oral toxicity study, totally 5 groups of Wistar albino rats of both sexes were used. Each group contains 5 males and 5 females. Group I which was set as control received RO water and Group II, III, IV, and V received 36, 180, 360, 360 mg/Kg b.wt of test drug respectively by oral administration. All the test animals were observed throughout the study period of 28 days and the satellite group for further 14 days. VKM did not produce any behavioural changes in all group of animals. ā– There was no significant changes in feed intake, water intake, and body weight. On 29th day animals were sacrificed and blood samples was collected and investigated.The results reveals that there were no significant changes in biochemical parameter,hematological parameter and lipid profile and Histopathological examination revealed normal architecture in comparison with control and treated animal.There is no abnormality was detected in organs of both control and test drug treated groups.These results have demonstrated that there is no toxic effects in all organs treated with VKM. Hence, VKM is safe when administered orallyin Wistar albino rats. ā– These 28 days repeated oral toxicity study results suggest the No Observed Adverse Effect Level (NOAEL) of Vasanthakusumakara Mathirai was found to be 360mg /Kgb.wt.so the drug is safe for human consumption. CONCLUSION: Vasanthakusumakara mathirai is one of the Siddha medicine which are widely used by the siddha system. It has specific indication to kaba diseases (Disease due to vitiated kabam),and also widely used for Respiratory disease.So the VKM was selected for preclinical study. ā– Vasanthakusumakara mathirai was taken as test drug, the quality parameters and safety profile of the drug were analyzed as per standard protocol. The qualitative and quantitative analysis of Vasanthakusumakara mathirai proved the quality and purity of thed rug. The quality assessment results will be used as standard for future research on Vasanthakusumakara mathirai. ā– The Acute toxicity study results did not show any mortality, behavioral changes and drug related toxicity. From the Acute toxicity study, it is revealed Vasanthakusumakara mathirai that is not toxic at maximum oral dose level of 2000mg/kg in Wistar rats, So, the median lethal dose MTD of is Vasanthakusumakara mathirai Less than 2000mg/Kgb.wt. ā– In Repeated Dose 28 Day oral toxicity study, There was no significant changes in hematological and biochemical parameters in vasanthakusumakara mathirai (360mg/kg b.wt) and histopathological parameters showed no significant changes in internal organs compared with control group. So, the No Observed Adverse Effect Level (NOAEL) of vasanthakusumakara mathirai was found to be 360mg/kg.b.wt.so the drug safe for human consumption. ā– Hence, the safety of vasanthakusumakara mathirai is proved through this study. From the study results, it is concluded that the therapeutic dose of 200mg (1-2 Mathirai) vasanthakusumakara mathirai is safe for human consumption. ā– Further clinical trials, Pharmacological studies and efficacy studies will be carried out on vasanthakusumakara mathirai to prove the efficacy of drug

    Preparation and evaluation of ionomeric membranes based on sulfonated-poly (styrene_isobutylene_styrene) membranes for proton exchange membrane fuel cells (PEMFC)

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    Sulfonated polystyrene-block-poly-(ethylene-ranbutylene)- block-polystyrene membranes with different sulfonated levels have been prepared and evaluated as proton exchange membrane for polymer electrolyte membrane fuel cell. The polymer was sulfonated by chlorosulfonic acid. Homogeneous membranes were prepared by solvent casting method. Ion exchange capacity, degree of sulfonation, absorption, and solubility of the membranes were studied. The membranes were characterized by Fourier transform infrared, thermogravimetric analyzer, differential scanning calorimetry, and impedance spectroscopy

    Studies on polymer modifiedmetal oxide anode for oxygen evolution reaction in saline water

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    Since most of the water source onthe earth surface issaline innature,hydrogen generation from saline water is ofgreat importance.Inthis paper,wehave developed amembrane protected anode,using anionic backbone ofsulfonated polystyrene-block-(ethylene-ran-butylene)-block-polystyrene polymer (S-PSEBS) over the anode (IrO2/Ti) which iscapable ofelectrostatically repelling the chloride ions (Cl) from the electrode surface and thereby enhancing the oxygen evolution rather than the chlorine evolu- tion. The electroche mical behavior ofboth polymer modifiedand bare IrO 2/Ti electrodes were characterized by electroche mical polarization studies and the gas evolution efficiencieswere calculated.The surface morpholog yofthe electrodes was investigated usi ngscanning electron microscope (SEM).The results suggest that nearly 95%oxygen evolutio nefficiencycould beachieved when the surface of IrO2/Ti electrode was modifiedwith apermselective membran
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