Investigation of the fracture behavior of woven fiber glass-reinforced low-density polyethylene composite

WOS:000283423400005The fracture behavior of woven fiber glass-reinforced low-density polyethylene thermoplastic composite having a middle tension specimen with inclined through-thickness cracks under static loading is studied in this article. Through the experiments, the topics crack growth, crack opening displacement (COD), stress intensity factors, and fracture toughness are studied. Crack growth amount and COD values are used as a damage parameter factor for crack geometry calculations. The consequent results of the experiments are inspected with J-integral method and stress intensity factor. Load-elongation and load-crack mouth opening displacement, the strain energy release rate-crack growth amount, stress intensity factor-crack growth amount graphics were drawn as the material properties under consideration

The Effect of Anthracycline Chemotherapy on Arterial Stiffness

Objective Anthracycline-derived chemotherapy for cancer treatment may cause dose-dependent irreversible heart failure. Arterial stifness is a predictor of cardiovascular events. Weaimed to investigate the relationship between chemotherapy and arterial stiffness.Materialsand MethodsPatients diagnosed non-Hodgkin's lymphoma, agreed to recieve anthracycline chemotherapy, were included in the study. Arterial stiffness was evaluated with applanationtonometer before, first and sixth cycles of chemotherapy.Results There was a tendency to increase first and sixth cycles pulse wave velocity values before anthracycline chemotherapy [9.08 (8.12-9.76), 10.31 (8.22-12.62), 9.64 (8.22-12.62)m/s, p = 0.053] but those changes were not reach statistically significance. Augmentation index change did not significantly change between anthracycline chemotherapycycles (p = 0.810). There was also a tendency to decrease first and sixth cycle subendocardial viabilty ratio values before151.60 (122.20-188.70) and after 124.30 (94.50-154.10), p = 0.058 chemotherapy.Conclusion Anthracycline chemotherapy tends to impaire arterial stiffness parameters

Ciddi Koroner Arter Hastalığı Olmayan Akut Koroner Sendrom Hastalarında Mortalite Değerlendirmesi

Amaç: Bu çalışmada, akut koroner sendromla başvuran fakat ciddi koroner arter hastalığı olmayan hastalarda bir yıllık sağkalım ve iliş‐ kili faktörlerin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Akut koroner sendrom tanısıyla koroner anjiyografi yapılan 150 hasta retrospektif olarak değerlendirildi. Hastane ve‐ ri tabanından demografik veriler, kardiyak risk faktörleri ve anjiyografik veriler kaydedildi. Bir yıllık sağkalım ve bununla ilişkili faktörler incelendi. Bulgular: Hastaların ortalama yaşı 62±13 yıldı ve %57'si (n=86) erkekti. Hastaların çoğu kararsız angına (%62) tanısı ile başvurmuştu. Sadece 11 hasta (%7,3) ST‐segment yükselmeli miyokard enfarktüsü tanısıyla hastaneye yatırıldı. Bir yıllık takip süresi boyunca tüm ça‐ lışma grubununda %5,3 (n=8) hastada ölüm meydana geldi. Mortalite, koroner ektazi grubunda ve troponin seviyesi yüksek olan has‐ talarda diğer gruplara göre istatistiksel olarak anlamlıydı (p=0,035). Sonuç: Akut koroner sendromla başvuran fakat ciddi koroner arter hastalığı olmayan hastalarda bir yıllık sağkalım yüksek troponin se‐ viyeleri ve ektazi‐yavaş akım varlığı ile ilişkili bulundu. Bu hastaların risk faktörleri kontrol altında tutulmalı ve hastalar daha yakın ta‐ kip edilmelidir.Objjective: This study aims to evaluate one year survey and related factors of patients with acute coronary syndrome but without sig‐ nificant coronary artery disease. Material and Method: One hundred and fifty patients who had coronary angiography with the diagnosis of acute coronary syndrome were evaluated retrospectively. Demographic data, cardiac risk factors, and angiographic data were recorded from the hospital database. The one year survey and associated factors were examined. Results: The mean age of the patients was 62 ± 13 years and 57% (n=86) were male. Most of the patients were diagnosed with unsta‐ ble angına (62%). Only 11 patients (7.3%) hospitalized with the diagnosis of ST‐segment elevation myocardial infarction. The death oc‐ curred in 5.3% of the whole study group during one year follow‐up period (n=8). Mortality was statistically significant in the coronary ectasia group and patients with high troponin levels when compared to other groups (p=0.035). Conclusion: One‐year survival in patients presenting with acute coronary syndrome but without severe coronary artery disease was found to be associated with high Troponin levels and the presence of ectasia‐slow flow. The risk factors of these patients should be kept under control and patients should be followed up more close

The prognostic value of T-peak T-end among patients with implantable cardiac defibrillator for secondary prevention

Aim: Cardiac death due to ventricular arrhyhtmias can occur in patients with ICD (implantable cardioverter defibrillator) for secondaryprevention. The aim of this study is to assess the prognostic value of electrocardiographic ventricular repolarization parameters inpatients with secondary prevention.Materials and Methods: Sixty five patients with ICD for secondary prevention after sustained ventricular tachycardia, ventricularfibrillation or sudden cardiac death were enrolled to the study retrospectively. Patients were divided into groups according tomortality during a follow up period of 4,5 years (48 patients alive and 17 dead). Heart rate, QT, QTc and T peak T end (Tp-e) durationwere measured from 12 derivations ECG electronically.Results: Mean age of the study population was 70.6±11.9 years. Ventricular repolarization parameters such as QT, QTc, Tp-e durationand Tp-e index values were found to be similar between deaths and live patient groups. Patients who died during the follow-up hadadvanced age (68.7±12.5 vs 76.8±10.3 years, p=0.009), lower left ventricular ejection fraction percentage (LVEF %) (37.6±13.3 vs26.9±9.2, p=0.003) and lower estimated glomerular filtration rate (81.2±22.5 vs 61±34.3 ml/min/m2, p=0.03). Arrhythmic deathpatients only had lower LVEF % than non-arrhythmic death patient’s group.Conclusions: In patients with ICD for secondary prevention QT, QTc, Tp-e duration and Tp-e index were not related to mortalit

Koroner Arter Kronik Total Oklüzyon Varlığının İmplanteEdilebilir Kardiyoverter Defibrilatörü Olan Hastaların UzunDönem Prognozu Üzerine Etkisi

Amaç: Kalp yetersizliği olan hastalarda kronik total oklüzyon varlığının mortalite artışı ile ilişkisi gösterilmiştir. Bu çalışmadaki amaç, intra kardiyak defibrilatörü bulunan iskemik kardiyomiyopatili hastalarda kronik total oklüzyon varlığının uzun dönem prognoz üzerine etkisini değerlendirmektir. Gereç ve Yötem: Birincil veya ikincil koruma amaçlı kardiyoverter defibrilatörü implante edilmiş 218 hastadan, iskemik kardiyomiyopatisi bulunan toplam 74 hasta çalışmaya alındı. Hastalar herhangi bir veya daha fazla koroner arterinde kronik total oklüzyon bulunanlar (n=32) ve bulunmayanlar (n=42) olmak üzere iki ana gruba, kronik total oklüzyon bulunan hastalar da miyokardiyal canlılığı olanlar (n=12) ve olmayanlar (n=20) olmak üzere alt gruplara ayrıldılar. Bulgular: 74 intrakardiyak defibrilatörü olan iskemik kardiyomiyopatili hastanın 32’sinde (%43,2) kronik total oklüzyon tespit edildi. Ortalama takip süresi olan 3,6 yılda tüm sebeplere bağlı 19 (%25,7) ölüm görüldü. Mortalite izlenen hastalarda ortalama yaş (p<0,001), ikincil koruma amaçlı intrakardiyak defibrilatörü bulunuşu (p=0,03) ve kronik obstrüktif akciğer hastalığı oranı (p=0,045) daha fazlaydı. Tüm sebeplerden ölüm için bağımsız prediktörler, ileri yaş (≥75) ve ikincil koruma amaçlı intrakardiyak defibrilatör varlığı idi. İntrakardiyak defibrilatörü olan iskemik kardiyomiyopatili hastalarda kronik total oklüzyon bulunuşunun uzun dönem prognoza etkisi yoktu (p=0,338). Sonuç: İntrakardiyak defibrilatörü olan iskemik kardiyomiyopati hastalarının herhangi bir koroner arterinde kronik total oklüzyon varlığı uzun dönem prognoza, intrakardiyak defibrilatörü şok ve akut dekompanse kalp yetersizliği sebepli hastaneye yatış oranları üzerine etkisi yoktur.Objective: It’s shown that the presence of chronic total occlusion was associated with increased mortality in patients with systolic heartfailure. The aim of this study was to evaluate the effect of chronic total occlusion on long term prognosis in patients with ischemic cardiomyopathy with intracardiac defibrillators.Material and Method: Of 218 patients implanted intracardiac defibrillator with primary or secondary prevention a total of 74 patientswith ischemic cardiomyopathy from 218 patients were included in the study. The patients were divided into two main groups; those withchronic total occlusion (n=32) in one or more coronary arteries and those without chronic total occlusion (n=42).Results: We detected 32 (%43.2) ischemic cardiomyopathy patients with intracardiac defibrillator had chronic total occlusion. The meanfollow up period was 3.6 years and 19 (25.7%) deaths were occurred within this period. Mean age (p<0.001), presence of intracardiacdefibrillator for secondary prevention (p=0.03) and chronic obstructive pulmonary disease (p=0.045) were found to be higher in patientswith mortality. Independent predictors of mortality were advanced age (≥75) and presence of intracardiac defibrillator for secondaryprevention not the presence of chronic total occlusion.Conclusion: The presence of chronic total occlusion in any coronary artery in patients with ischemic cardiomyopathy with intracardiacdefibrillator was not found to effect long term prognosis and hospitalization rates due intracardiac defibrillator shock or acute decompansated heart failure