Statistical characterization of roughness uncertainty and impact on wind resource estimation

In this work we relate uncertainty in background roughness length (z0) to uncertainty in wind speeds, where the latter are predicted at a wind farm location based on wind statistics observed at a different site. Sensitivity of predicted winds to roughness is derived analytically for the industry-standard European Wind Atlas method, which is based on the geostrophic drag law. We statistically consider roughness and its corresponding uncertainty, in terms of both z0 derived from measured wind speeds as well as that chosen in practice by wind engineers. We show the combined effect of roughness uncertainty arising from differing wind-observation and turbine-prediction sites; this is done for the case of roughness bias as well as for the general case. For estimation of uncertainty in annual energy production (AEP), we also develop a generalized analytical turbine power curve, from which we derive a relation between mean wind speed and AEP. Following our developments, we provide guidance on approximate roughness uncertainty magnitudes to be expected in industry practice, and we also find that sites with larger background roughness incur relatively larger uncertainties

Frequency response in surface-potential driven electro-hydrodynamics

Using a Fourier approach we offer a general solution to calculations of slip velocity within the circuit description of the electro-hydrodynamics in a binary electrolyte confined by a plane surface with a modulated surface potential. We consider the case with a spatially constant intrinsic surface capacitance where the net flow rate is in general zero while harmonic rolls as well as time-averaged vortex-like components may exist depending on the spatial symmetry and extension of the surface potential. In general the system displays a resonance behavior at a frequency corresponding to the inverse RC time of the system. Different surface potentials share the common feature that the resonance frequency is inversely proportional to the characteristic length scale of the surface potential. For the asymptotic frequency dependence above resonance we find a 1/omega^2 power law for surface potentials with either an even or an odd symmetry. Below resonance we also find a power law omega^alpha with alpha being positive and dependent of the properties of the surface potential. Comparing a tanh potential and a sech potential we qualitatively find the same slip velocity, but for the below-resonance frequency response the two potentials display different power law asymptotics with alpha=1 and alpha~2, respectively.Comment: 4 pages including 1 figure. Accepted for PR

Exogenous Ether Lipids Predominantly Target Mitochondria

Ether lipids are ubiquitous constituents of cellular membranes with no discrete cell biological function assigned yet. Using fluorescent polyene-ether lipids we analyzed their intracellular distribution in living cells by microscopy. Mitochondria and the endoplasmic reticulum accumulated high amounts of ether-phosphatidylcholine and ether-phosphatidylethanolamine. Both lipids were specifically labeled using the corresponding lyso-ether lipids, which we established as supreme precursors for lipid tagging. Polyfosine, a fluorescent analogue of the anti-neoplastic ether lipid edelfosine, accumulated to mitochondria and induced morphological changes and cellular apoptosis. These data indicate that edelfosine could exert its pro-apoptotic power by targeting and damaging mitochondria and thereby inducing cellular apoptosis. In general, this study implies an important role of mitochondria in ether lipid metabolism and intracellular ether lipid trafficking