Physicochemical Properties and Enzymes Activity Studies in a Refined Oil Contaminated Soil in Isiukwuato, Abia State, Nigeria

Soil Physicochemical properties and enzyme concentration were evaluated in soil from a refined-oil contaminated community in Isiukwuato, Abia State three years after the spill. The soil enzymes examined were urease, lipase, oxidase, alkaline and acid phosphatases. Results show a significant (P< 0.05) decrease in the activities of these enzymes in the contaminatedsoil relative to the control. Soil temperature, Organic Carbon(OC), Organic Matter (OM), Exchangeable Acidity (EA), Saturation Base (SB) and Effective Cation Exchangeable Capacity (ECEC) were significantly higher (

Dense Deposit Disease: A 29-Years Electron Microscopy Experience

Introduction: Dense Deposit Disease (DDD) is a devastating renal disease that leads to renal failure within 10 years of diagnosis in about half of affected patients. In this study, we evaluated the relative prevalence and pathological features of DDD diagnosed at our center over a 29 years period.Methods: We reviewed the clinical and pathological features of all cases of DDD diagnosed at the Electron Microscopy Unit of Ain Shams University (ASUSH) between January 1983 and December 2011.Results: From a total of 3283 renal biopsies, 33 (1%) were diagnosed with DDD (10 children and 23 adults). Nephrotic syndrome was the predominant clinical presentation of DDD (51.5%), and was commoner in children than adults (80% vs. 43%, p=0.03). Capillary wall thickening was seen in all cases (100%). Crescents were more commonly seen in children than adults (70% vs. 21.7%, p=0.008) while interstitial fibrosis was more commonly seen in adults (78.3% vs. 40%, p=0.03). The commonest histological pattern seen under light microscopy was membranoproliferative (27.3%), followed by crescentic (21.2%), membranous (21.2%), diffuse proliferative (18.2%), lobular (6.1%) and mesangial proliferative (6.1%) patterns. Immunohistochemistry was available for 25 cases and showed intense linear staining for C3 along capillary walls. Electron microscopic examination revealed glomerular basement membrane (GBM) thickening and intra-membranous and tubular basement membrane deposits in all cases (100%).Conclusion: DDD is a rare disease in Egypt, found in only 1% of renal biopsies. Pathological features of the disease differ between adults and children; children have predominantly glomerular damage whereas tubule-interstitial lesions are more often encountered in adults.Key words: Dense Deposit Disease; Electron Microscopy; Membranoproliferative Glomerulonephritis; Nephrotic Syndrom

Effect of upgraded emergency services on obstetric case fatality at a Tertiary Hospital in Cross River state, Nigeria

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Continuous belief functions and α-stable distributions

International audienceThe theory of belief functions has been formalized in continuous domain for pattern recognition. Some applications use assumption of Gaussian models. However, this assumption is reductive. Indeed, some data are not symmetric and present property of heavy tails. It is possible to solve these problems by using a class of distributions called α-stable distributions. Consequently, we present in this paper a way to calculate pignistic probabilities with plausibility functions where the knowledge of the sources of information is represented by symmetric α-stable distributions. To validate our approach, we compare our results in special case of Gaussian distributions with existing methods. To illustrate our work, we generate arbitrary distributions which represents speed of planes and take decisions. A comparison with a Bayesian approach is made to show the interest of the theory of belief functions

Impact of Stratospheric Aerosol Geoengineering on Extreme Precipitation and Temperature indices in West Africa using GLENS simulations

This study assesses changes in extremes precipitation and temperature in West Africa under a high greenhouse gas scenario, i.e. a representative concentration pathway 8.5 (RCP8.5), and under a scenario of stratospheric aerosol geoengineering (SAG) deployment using the NCAR Community Earth System Model version 1 (CESM1-WACCM). We use results from the Geoengineering Large Ensemble (GLENS) simulations, where SAG is deployed to keep global surface temperatures at present day values. This impact study evaluates changes in some of the extreme climate indices recommended by the Expert Team Monitoring on Climate Change Detection and Indices (ETCCDI). The results indicate that SAG would effectively keep surface temperatures at present day-conditions across a range of indices compared to the control period, including Cold days, Cold nights and Cold Spell Duration Indicator which show no significant increase compared to the control period. Regarding the extremes precipitation, GLENS shows mostly a statistically significant increase in annual precipitation and statistically significant decrease in the number of heavy and very heavy precipitation events relative to the control period in some regions of Gulf of Guinea. In the Sahel, we notice a mix of statistically significant increase and decrease in Max 1-day and Max 5-days precipitation amount relative to the control period at the end of the 21st century when large amounts of SAG has been applied. The changes in extreme precipitation indices are linked to changes in Atlantic Multidecadal Oscillation (AMO), NINO3.4 and Indian Ocean Dipole (IOD) and these changes in extreme precipitation are driven by change in near surface specific humidty and atmospheric circulation

Pattern of Respiratory Viruses among Pilgrims during 2019 Hajj Season Who Sought Healthcare Due to Severe Respiratory Symptoms

The aim of our study was to define the spectrum of viral infections in pilgrims with acute respiratory tract illnesses presenting to healthcare facilities around the holy places in Makkah, Saudi Arabia during the 2019 Hajj pilgrimage. During the five days of Hajj, a total of 185 pilgrims were enrolled in the study. Nasopharyngeal swabs (NPSs) of 126/185 patients (68.11%) tested positive for one or more respiratory viruses by PCR. Among the 126 pilgrims whose NPS were PCR positive: (a) there were 93/126 (74%) with a single virus infection, (b) 33/126 (26%) with coinfection with more than one virus (up to four viruses): of these, 25/33 cases had coinfection with two viruses; 6/33 were infected with three viruses, while the remaining 2/33 patients had infection with four viruses. Human rhinovirus (HRV) was the most common detected viruses with 53 cases (42.06%), followed by 27 (21.43%) cases of influenza A (H1N1), and 23 (18.25%) cases of influenza A other than H1N1. Twenty-five cases of CoV-229E (19.84%) were detected more than other coronavirus members (5 CoV-OC43 (3.97%), 4 CoV-HKU1 (3.17%), and 1 CoV-NL63 (0.79%)). PIV-3 was detected in 8 cases (6.35%). A single case (0.79%) of PIV-1 and PIV-4 were found. HMPV represented 5 (3.97%), RSV and influenza B 4 (3.17%) for each, and Parechovirus 1 (0.79%). Enterovirus, Bocavirus, and M. pneumoniae were not detected. Whether identification of viral nucleic acid represents nasopharyngeal carriage or specific causal etiology of RTI remains to be defined. Large controlled cohort studies (pre-Hajj, during Hajj, and post-Hajj) are required to define the carriage rates and the specific etiology and causal roles of specific individual viruses or combination of viruses in the pathogenesis of respiratory tract infections in pilgrims participating in the annual Hajj. Studies of the specific microbial etiology of respiratory track infections (RTIs) at mass gathering religious events remain a priority, especially in light of the novel SARS-CoV-2 pandemic

Dermatological Toxicity of Hydroxycarbamide

Hydroxycarbamide is an antitumor agent mainly used for treatment of Ph-negative myeloproliferative disorders and sickle cell disease. The development of skin ulcers is a rare but serious adverse event in long-term antitumor therapy. Hydroxycarbamide-induced ulcers are often multiple and bilateral, and usually occur in the lower legs, although they can occur in other regions of the body. The ulcers are small-sized and shallow with sharp margins and yellow fibrine-covered base. They cause constant severe, difficult to treat pain which is a characteristic sign. The drug withdrawal usually leads to spontaneous healing of ulcers. Regular dermatologic screening must be obligatory for all the patients receiving hydroxycarbamide. The present paper provides a literature review on dermatological toxicity of hydroxycarbamide and a clinical case description

Electrical control over single hole spins in nanowire quantum dots

Single electron spins in semiconductor quantum dots (QDs) are a versatile platform for quantum information processing, however controlling decoherence remains a considerable challenge. Recently, hole spins have emerged as a promising alternative. Holes in III-V semiconductors have unique properties, such as strong spin-orbit interaction and weak coupling to nuclear spins, and therefore have potential for enhanced spin control and longer coherence times. Weaker hyperfine interaction has already been reported in self-assembled quantum dots using quantum optics techniques. However, challenging fabrication has so far kept the promise of hole-spin-based electronic devices out of reach in conventional III-V heterostructures. Here, we report gate-tuneable hole quantum dots formed in InSb nanowires. Using these devices we demonstrate Pauli spin blockade and electrical control of single hole spins. The devices are fully tuneable between hole and electron QDs, enabling direct comparison between the hyperfine interaction strengths, g-factors and spin blockade anisotropies in the two regimes

Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery

<p>Abstract</p> <p>Background</p> <p>To compare the clinical efficacy of lidocaine 2% with tetracaine 0.5% for cataract surgery.</p> <p>Methods</p> <p>In a randomized, multi-surgeon, controlled clinical trial,122 consecutive cataract cases eligible for topical anesthesia, were randomly assigned to receive lidocaine 2% gel (1 ml) or tetracaine solution 0.5% (TetraVisc, 0.5 ml) before clear corneal phacoemulsification. Main outcome measure was visual analog scale (0 to 10), which was used to measure intra-operative pain. Secondary outcome measures included patients' discomfort due to tissue manipulation and surgeon graded patients' cooperation. Duration of surgery and intra-operative complications were also recorded.</p> <p>Results</p> <p>The mean age in TetraVisc (TV) group was 70.4 years and in the lidocaine gel group (LG) it was 70.6 years (p = 0.89). Patient reported mean intra-operative pain scores by visual analog scale were 0.70 ± 0.31 in TV group and 1.8 ± 0.4 in LG group (<it>P </it>< 0.001). Mean patient cooperation was also marginally better in the TV group (8.3 ± 0.3) compared to LG group (8.4 ± 0.6) (P = 0.25). 96% of patients in TV group showed intra-operative corneal clarity compared to 91% in LG group. TV group had less (1 out of 61 patients, 1.6%) intra-operative complications than LG group (3 out of 61 patients, 4.8%). No anesthesia related complications were noted in either group</p> <p>Conclusion</p> <p>Topical TetraVisc solution was superior to lidocaine 2% gel for pain control in patients undergoing clear corneal phacoemulsification. Lidocaine 2% gel is similar to TetraVisc in patient comfort and surgeon satisfaction.</p> <p>Trial Registration</p> <p><b>Clinical trials number</b>: ISRCTN78374774</p