3 research outputs found

    Needs assessment to strengthen capacity in water and sanitation research in Africa:experiences of the African SNOWS consortium

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    Despite its contribution to global disease burden, diarrhoeal disease is still a relatively neglected area for research funding, especially in low-income country settings. The SNOWS consortium (Scientists Networked for Outcomes from Water and Sanitation) is funded by the Wellcome Trust under an initiative to build the necessary research skills in Africa. This paper focuses on the research training needs of the consortium as identified during the first three years of the project

    Impact of insecticide-treated bed nets on malaria transmission indices on the south coast of Kenya

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    <p>Abstract</p> <p>Background</p> <p>Besides significantly reducing malaria vector densities, prolonged usage of bed nets has been linked to decline of <it>Anopheles gambiae </it>s.s. relative to <it>Anopheles arabiensis</it>, changes in host feeding preference of malaria vectors, and behavioural shifts to exophagy (outdoor biting) for the two important malaria vectors in Africa, <it>An. gambiae </it>s.l. and <it>Anopheles funestus</it>. In southern coastal Kenya, bed net use was negligible in 1997-1998 when <it>Anopheles funestus </it>and <it>An. gambiae </it>s.s. were the primary malaria vectors, with <it>An. arabiensis </it>and <it>Anopheles merus </it>playing a secondary role. Since 2001, bed net use has increased progressively and reached high levels by 2009-2010 with corresponding decline in malaria transmission.</p> <p>Methods</p> <p>To evaluate the impact of the substantial increase in household bed net use within this area on vector density, vector composition, and human-vector contact, indoor and outdoor resting mosquitoes were collected in the same region during 2009-2010 using pyrethrum spray catches and clay pots for indoor and outdoor collections respectively. Information on bed net use per sleeping spaces and factors influencing mosquito density were determined in the same houses using Poisson regression analysis. Species distribution was determined, and number of mosquitoes per house, human-biting rates (HBR), and entomological inoculation rate (EIR) were compared to those reported for the same area during 1997-1998, when bed net coverage had been minimal.</p> <p>Results</p> <p>Compared to 1997-1998, a significant decline in the relative proportion of <it>An. gambiae </it>s.s. among collected mosquitoes was noted, coupled with a proportionate increase of <it>An. arabiensis</it>. Following > 5 years of 60-86% coverage with bed nets, the density, human biting rate and EIR of indoor resting mosquitoes were reduced by more than 92% for <it>An. funestus </it>and by 75% for <it>An. gambiae </it>s.l. In addition, the host feeding choice of both vectors shifted more toward non-human vertebrates. Besides bed net use, malaria vector abundance was also influenced by type of house construction and according to whether one sleeps on a bed or a mat (both of these are associated with household wealth). Mosquito density was positively associated with presence of domestic animals.</p> <p>Conclusions</p> <p>These entomological indices indicate a much reduced human biting rate and a diminishing role of <it>An. gambiae </it>s.s. in malaria transmission following high bed net coverage. While increasing bed net coverage beyond the current levels may not significantly reduce the transmission potential of <it>An. arabiensis</it>, it is anticipated that increasing or at least sustaining high bed net coverage will result in a diminished role for <it>An. funestus </it>in malaria transmission.</p

    Worms: Identifying Impacts on Education and Health in the Presence of Treatment Externalities

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    Intestinal helminths-including hookworm, roundworm, whipworm, and schistosomiasis-infect more than one-quarter of the world's population. Studies in which medical treatment is randomized at the individual level potentially doubly underestimate the benefits of treatment, missing externality benefits to the comparison group from reduced disease transmission, and therefore also underestimating benefits for the treatment group. We evaluate a Kenyan project in which school-based mass treatment with deworming drugs was randomly phased into schools, rather than to individuals, allowing estimation of overall program effects. The program reduced school absenteeism in treatment schools by one-quarter, and was far cheaper than alternative ways of boosting school participation. Deworming substantially improved health and school participation among untreated children in both treatment schools and neighboring schools, and these externalities are large enough to justify fully subsidizing treatment. Yet we do not find evidence that deworming improved academic test scores. Copyright Econometric Society 2004.
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