The Intermediate Luminosity Optical Transient SN 2010da: The Progenitor, Eruption and Aftermath of a Peculiar Supergiant High-mass X-ray Binary

We present optical spectroscopy, ultraviolet to infrared imaging and X-ray observations of the intermediate luminosity optical transient (ILOT) SN 2010da in NGC 300 (d=1.86 Mpc) spanning from -6 to +6 years relative to the time of outburst in 2010. Based on the light curve and multi-epoch SEDs of SN 2010da, we conclude that the progenitor of SN 2010da is a ~10-12 Msol yellow supergiant possibly transitioning into a blue loop phase. During outburst, SN 2010da had a peak absolute magnitude of M<-10.4 mag, dimmer than other ILOTs and supernova impostors. We detect multi-component hydrogen Balmer, Paschen, and Ca II emission lines in our high-resolution spectra, which indicate a dusty and complex circumstellar environment. Since the 2010 eruption, the star has brightened by a factor of ~5 and remains highly variable in the optical. Furthermore, we detect SN 2010da in archival Swift and Chandra observations as an ultraluminous X-ray source (L~6x10^{39} erg/s). We additionally attribute He II 4686 Angstrom and coronal Fe emission lines in addition to a steady X-ray luminosity of ~10^{37} erg/s to the presence of a compact companion.Comment: published; updated citations and other minor edit

Penggunaan Blok Persegi Termodifikasi Dan Trapesium Dalam Perencanaan Beton Mutu Tinggi Dan Sangat Tinggi

Tujuan dari penelitian ini adalah untuk mendapatkan tatacara perencanaan beton mutu tinggi dan sangat tinggi dengan menggunakan blok pendekatan persegi yang termodifikasi dan blok trapesium. Penelitian dimulai dengan studi literatur dan perhitungan luasan diagram interaksi tegangan regangan beton. Setelah itu dilakukan ekuivalensi antara luasan diagram interaksi tegangan regangan dan luasan blok pendekatan, kemudian diperoleh koefisien-koefisien penyesuaian. Langkah selanjutnya adalah menurunkan rumus yang mengandung koefisien penyesuaian untuk mendapatkan rasio tulangan perlu dan langkah yang terakhir adalah menyusun tata cara perencanaan beton bertulang mutu tinggi dan sangat tinggi. Mutu beton yang ditinjau dalam penelitian ini adalah beton dengan mutu 15 – 120 MPa. Untuk pendekatan persegi termodifikasi diperoleh koefisien penyesuaian β1 berkisar antara 0.68 sampai 0.98, dengan 0.68 merupakan nilai β1 untuk beton 120 MPa sedangkan 0.98 untuk beton 15 MPa. Nilai β1 tersebut adalah nilai yang aman karena telah sesuai dengan syarat nilai β1 menurut SNI 03-2847-2002 yaitu β1 ≥ 0.65.Untuk pendekatan trapesium diperoleh nilai koefisien α untuk penyesuaian luasan berkisar antara 0.16 sampai 0.63, sedangkan untuk koefisien penyesuaian titik berat (γ) berkisar antara 0.0061 sampai 0.0222. The purpose of the research is to obtained a design procedure for flexure design of high strength and ultra high strength concrete; using modified rectangular block and trapezoidal block approaches. Analytical and design equations were formulated for each of the approaches, then by equating area of the block with that of actual stress-strain diagram, and internal moment of the force of the block to that of the actual stress-strain diagram, characeristic coefficients of each aproach were determined and adjusted. The procedure was done on high and ultra-high strength concrete (fc' in the range of 15 to 120 MPa. The value of β1 ¬–coefficient for modified rectangular block approach was found to be in the range of 0.68 to 0.98, where 0.68 is β1 for 120 MPa and 0.98 for 15 MPa. These values are safe as it complies with the value required for it by SNI 03-2847-2002 namely that β1 ¬¬must be greater than 0.65. For the trapezoidal block approach there are two coefficients. They are α, coefficient for the area adjustment and γ, coefficient for the adjustment of center of mass. The research yielded that α is in the range of 0.16 to 0.63 and γ is in the range of 0.0061 to 0.0222. Design procedure was then prepared using each of the approach based on their respective characteristic coefficients

Peran Kepala Sekolah Dalam Meningkatkan Nilaikelulusan Siswa/i Di SMP Negeri 1 Percut Sei Tuan Kabupaten Deli Serdang

The problem in this study is to examine the principal's task in increasing student graduation scores at SMP Negeri 1 Percut Sei Tuan, Deli Serdang Regency, which finally succeeded in increasing good student graduation scores, as seen from the 2017-2019 students' graduation scores which continued to increase with 100% percentage, students get a decent grade point average, and students are admitted to college, in a consistently evolving world of business and industry. To make it easier to follow and develop all that is obtained, the principalis constantly looking for solutions on the most appropriate way to maintain the quality of alumni. Then the principal is used as a motivation to increase the passing grade. This research is a descriptive study with qualitative analysis and takes place in SMP Negeri 1 Percut Sei Tuan, Deli Serdang Regency. Subjects in this study were principals and vice principals for student affairs. The data collection techniques used were observation, interviews, and documentation and the data analysis technique used was the Spradley model. To check the validity of the data, the researcher used triangulation. The results of the study indicate that the principal plays an important role in Improving the Graduation Value of Students /I in SMP Negeri 1 Percut Sei Tuan Deli Serdang Regency

Coupling emission from single localized defects in 2D semiconductor to surface plasmon polaritons

Coupling of an atom-like emitter to surface plasmons provides a path toward significant optical nonlinearity, which is essential in quantum information processing and quantum networks. A large coupling strength requires nanometer-scale positioning accuracy of the emitter near the surface of the plasmonic structure, which is challenging. We demonstrate the coupling of single localized defects in a tungsten diselenide (WSe2) monolayer self-aligned to the surface plasmon mode of a silver nanowire. The silver nanowire induces a strain gradient on the monolayer at the overlapping area, leading to the formation of localized defect emission sites that are intrinsically close to the surface plasmon. We measure a coupling efficiency with a lower bound of 39% from the emitter into the plasmonic mode of the silver nanowire. This technique offers a way to achieve efficient coupling between plasmonic structures and localized defects of 2D semiconductors

Corticomotor responses to attentionally demanding motor performance: a mini-review

Increased attentional demand has been shown to reduce motor performance, leading to increases in accidents, particularly in elderly populations. While these deficits have been well documented behaviorally, their cortical correlates are less well known. Increased attention has been shown to affect activity in prefrontal regions of the cortex. However there have been varying results within past research investigating corticomotor regions, mediating motor performance. This mini-review initially discusses past behavioral research, before moving to studies investigating corticomotor areas in response to changes in attention. Recent dual task studies have revealed a possible decline in the ability of older, but not younger, adults to activate inhibitory processes within the motor cortex, which may be correlated with poor motor performance, and thus accidents. A reduction in cortical inhibition may be caused by neurodegeneration within prefrontal regions of the cortex with age, rendering older adults less able to allocate attention to corticomotor regions

Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

BACKGROUND: Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in normal and leukemic hematopoiesis. However, the manner in which STAT5 responds to early-acting and lineage-restricted cytokines, particularly in leukemic stem/progenitor cells, is largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: We optimized a multiparametric flow cytometry protocol to analyze STAT5 phosphorylation upon cytokine stimulation in stem and progenitor cell compartments at a single-cell level. In normal cord blood (CB) cells, STAT5 phosphorylation was efficiently induced by TPO, IL-3 and GM-CSF within CD34(+)CD38(-) hematopoietic stem cells (HSCs). EPO- and SCF-induced STAT5 phosphorylation was largely restricted to the megakaryocyte-erythroid progenitor (MEP) compartment, while G-CSF as well IL-3 and GM-CSF were most efficient in inducing STAT5 phosphorylation in the myeloid progenitor compartments. Strikingly, mobilized adult peripheral blood (PB) CD34(+) cells responded much less efficiently to cytokine-induced STAT5 activation, with the exception of TPO. In leukemic stem and progenitor cells, highly distinct cytokine responses were observed, differing significantly from their normal counterparts. These responses could not be predicted by the expression level of cytokine receptors. Also, heterogeneity existed in cytokine requirements for long-term expansion of AML CD34(+) cells on stroma. CONCLUSIONS/SIGNIFICANCE: In conclusion, our optimized multiparametric flow cytometry protocols allow the analysis of signal transduction at the single cell level in normal and leukemic stem and progenitor cells. Our study demonstrates highly distinctive cytokine responses in STAT5 phosphorylation in both normal and leukemic stem/progenitor cells