1,846 research outputs found
Science Leadership: Impact of the New Science Coordinators Academy
This article discusses the impact of the New Science Coordinators Academy (NSCA) on two cohorts of participants. The NSCA is one of four components of the Virginia Initiative for Science Teaching and Achievement (VISTA), a United States Department of Education (USED) science education reform grant. The NSCA is designed to support new school district science coordinators (with less than five years of experience) and to continue building the state science education infrastructure. Research in education leadership traditionally focuses on teacher leaders, principals, and district office personnel. Interestingly, research on district office personnel rarely distinguishes between the different roles of district personnel. This article seeks to inform the field by sharing the impact of an academy designed for new science coordinators on their learning, and to begin to understand their role and impact in their district. The five-day Academy engaged participants in a variety of experiences designed to facilitate the following: 1) build leadership skills; 2) build a common understanding and vision for hands-on science, inquiry, problem-based learning, and nature of science in the science classroom; 3) investigate data to improve student learning goals; 4) and, develop a science strategic plan. The data indicate that the NSCA was successful at meeting its goals to support the participants and to build a common language among these new coordinators. Initial data also support the variety of responsibilities of these participants and the positive impact of the Academy on their district work
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The association of short sleep after acute coronary syndrome with recurrent cardiac events and mortality
Although most patients survive an acute coronary syndrome (ACS; myocardial infarction [MI] or unstable angina [UA]), within 5â
years 22% will be re-hospitalized and more than 1 in 3 will die [1]. Thus, identifying modifiable risk factors for ACS recurrence and mortality is critical
Fingerprints of biocomplexity: Taxonâspecific growth of phytoplankton in relation to environmental factors
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110012/1/lno2004494part21446.pd
Meta-Analysis of Perceived Stress and Its Association With Incident Coronary Heart Disease
Most studies examining potential associations between psychological factors and cardiovascular outcomes have focused on depression or anxiety. The effect of perceived stress on incident coronary heart disease (CHD) has yet to be reviewed systematically. We conducted a systematic review and meta-analysis of the association between perceived stress and incident CHD. Ovid, MEDLINE, and PsycINFO were searched as data sources. Prospective observational cohort studies were selected that measured self-reported perceived stress and assessed incident CHD at â„6 months. We extracted study characteristics and estimates of the risk of incident CHD associated with high perceived stress versus low perceived stress. We identified 23 potentially relevant articles, of which 6 met our criteria (n = 118,696). Included studies measured perceived stress with validated measurements and nonvalidated simple self-report surveys. Incident CHD was defined as new diagnosis of, hospitalization for, or mortality secondary to CHD. Meta-analysis yielded an aggregate risk ratio of 1.27 (95% confidence interval 1.12 to 1.45) for the magnitude of the relation between high perceived stress and incident CHD. In conclusion, this meta-analysis suggests that high perceived stress is associated with a moderately increased risk of incident CHD
Cladoceran birth and death rates estimates
I. Birth and death rates of natural cladoceran populations cannot be measured directly. Estimates of these population parameters must be calculated using methods that make assumptions about the form of population growth. These methods generally assume that the population has a stable age distribution.
2. To assess the effect of variable age distributions, we tested six egg ratio methods for estimating birth and death rates with data from thirty-seven laboratory populations of Daphnia pulicaria. The populations were grown under constant conditions, but the initial age distributions and egg ratios of the populations varied. Actual death rates were virtually zero, so the difference between the estimated and actual death rates measured the error in both birth and death rate estimates.
3. The results demonstrate that unstable population structures may produce large errors in the birth and death rates estimated by any of these methods. Among the methods tested, Taylor and Slatkin's formula and Paloheimo's formula were most reliable for the experimental data.
4. Further analyses of three of the methods were made using computer simulations of growth of age-structured populations with initially unstable age distributions. These analyses show that the time interval between sampling strongly influences the reliability of birth and death rate estimates. At a sampling interval of 2.5 days (equal to the duration of the egg stage), Paloheimo's formula was most accurate. At longer intervals (7.5â10 days), Taylor and Slatkin's formula which includes information on population structure was most accurate
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Vitamin D Supplementation for Depressive Symptoms: A Systematic Review and Meta-analysis of Randomized Controlled Trials
OBJECTIVE:
The aim of this study was to review the effects of vitamin D supplementation on depressive symptoms in randomized controlled trials. Although low vitamin D levels have been observationally associated with depressive symptoms, the effect of vitamin D supplementation as an antidepressant remains uncertain.
METHODS:
MEDLINE, CINAHL, AMED, PsycINFO, Scopus, The Cochrane Library, and references of included reports (through May 2013) were searched. Two independent reviewers identified and extracted data from randomized trials that compared the effect of vitamin D supplementation on depressive symptoms to a control condition. Two additional reviewers assessed study quality using The Cochrane Risk of Bias Tool. Seven trials (3191 participants) were included.
RESULTS:
Vitamin D supplementation had no overall effect on depressive symptoms (standardized mean difference [SMD], 0.14; 95% confidence interval [CI], -0.33 to 0.05, p = .16), although considerable heterogeneity was observed. Subgroup analysis showed that vitamin D supplementation for participants with clinically significant depressive symptoms or depressive disorder had a moderate, statistically significant effect (2 studies: SMD, -0.60; 95% CI, -1.19 to -0.01; p = .046), but a small, nonsignificant effect for those without clinically significant depression (5 studies: SMD, -0.04; 95% CI, -0.20 to 0.12; p = .61). Most trials had unclear or high risk of bias. Studies varied in the amount, frequency, duration, and mode of delivery of vitamin D supplementation.
CONCLUSIONS:
Vitamin D supplementation may be effective for reducing depressive symptoms in patients with clinically significant depression; however, further high-quality research is needed
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Concurrent Stress and Depressive Symptoms Increase Risk of Myocardial Infarction or Death
BACKGROUND: Depression and stress have each been found to be associated with poor prognosis in patients with coronary heart disease. A recently offered psychosocial perfect storm conceptual model hypothesizes amplified risk will occur in those with concurrent stress and depressive symptoms. We tested this hypothesis in a large sample of US adults with coronary heart disease. METHODS AND RESULTS: Participants included 4487 adults with coronary heart disease from the Reasons for Geographic and Racial Differences in Stroke study, a prospective cohort study of 30,239 black and white adults. We conducted Cox proportional hazards regression with the composite outcome of myocardial infarction or death and adjustment for demographic, clinical, and behavioral factors. Overall, 6.1% reported concurrent high stress and high depressive symptoms at baseline. During a median 5.95 years of follow-up, 1337 events occurred. In the first 2.5 years of follow-up, participants with concurrent high stress and high depressive symptoms had increased risk for myocardial infarction or death (adjusted hazard ratio, 1.48 [95% confidence interval, 1.08-2.02]) relative to those with low stress and low depressive symptoms. Those with low stress and high depressive symptoms (hazard ratio, 0.92 [95% confidence interval, 0.66-1.28]) or high stress and low depressive symptoms (hazard ratio, 0.86 [95% confidence interval, 0.57-1.29]) were not at increased risk. The association on myocardial infarction or death was not significant after the initial 2.5 years of follow-up (hazard ratio, 0.89 [95% confidence interval, 0.65-1.22]). CONCLUSIONS: Our results provide initial support for a psychosocial perfect storm conceptual model; the confluence of depressive symptoms and stress on medical prognosis in adults with coronary heart disease may be particularly destructive in the shorter term
An inexpensive device for monitoring patients' weights via automated hovering
Daily weight monitoring is integral to the management of heart failure (HF) [1]. Indeed, weight gain is a marker of HF decompensation, and daily weight monitoring has been associated with favorable prognosis [2]. Until now, assessment of weight has required patients to attend an in-person visit, which provides only an infrequent snapshot of their weight. Remote hovering practices have gained considerable traction during the past several years [3â7], but their use outside of research settings has been limited
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Effects of Concurrent Depressive Symptoms and Perceived Stress on Cardiovascular Risk in Lowâ and HighâIncome Participants: ...
Background: Psychosocial risk for cardiovascular disease (CVD) may be especially deleterious in persons with low socioeconomic status. Most work has focused on psychosocial factors individually, but emerging research suggests that the confluence of psychosocial risk may be particularly harmful. Using data from the Reasons for Geographical and Racial Differences in Stroke (REGARDS) study, we examined associations among depressive symptoms and stress, alone and in combination, and incident CVD and allâcause mortality as a function of socioeconomic status.
Methods and Results At baseline, 22 658 participants without a history of CVD (58.8% female, 41.7% black, mean age 63.9±9.3 years) reported on depressive symptoms, stress, annual household income, and education. Participants were classified into 1 of 3 psychosocial risk groups at baseline: (1) neither depressive symptoms nor stress, (2) either depressive symptoms or stress, or (3) both depressive symptoms and stress. Cox proportional hazards models were used to predict physicianâadjudicated incident total CVD events (nonfatal myocardial infarction, nonfatal stroke, and cardiovascular death) and allâcause mortality over a median of 7.0 years (interquartile range 5.4â8.3 years) of followâup. In fully adjusted models, participants with both depressive symptoms and stress had the greatest elevation in risk of developing total CVD (hazard ratio 1.48, 95% CI 1.21â1.81) and allâcause mortality (hazard ratio 1.33, 95% CI 1.13â1.56) but only for those with low income (< 35 000) income. This pattern of results was not observed in models stratified by education.
Conclusions Findings suggest that screening for a combination of elevated depressive symptoms and stress in lowâincome persons may help identify those at increased risk of incident CVD and mortality
Preliminary assessment of the irradiation behaviour of the FeCrMnNi High-Entropy Alloy for nuclear applications
In the search for new nuclear materials with improved radiation tolerance and behavior, the high-entropy
alloys (HEAs) have arisen as new candidates for structural components in nuclear reactors due to their
suspected superior stability under irradiation. The metallurgical definition of HEAs is any alloy with
multiple elements, five or more all in equiatomic compositions. The basic principle is the high mixing
entropy of its solid solution lowers the Gibbs free energy giving a strong enhancement of the
microstructural stability at low and high temperatures.
The objective of this project is to assess the irradiation behaviour of the FeCrMnNi HEA system in order
to investigate whether the high entropy effect is responsible for a microstructure with better radiation
resistance compared to conventional alloys. In this work transmission electron microscopy (TEM) with
in-situ ion irradiation has been used at the MIAMI-1 facility at the University of Huddersfield, UK: a 100
kV ion accelerator coupled with a JEOL JEM-2000FX TEM. This methodology allows the evolution of
the HEA microstructure to be studied on the nanoscale during the ion irradiation
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