1,620 research outputs found
Yaws and syphilis in contrast comparison and combination: based on short course mass treatment in East Africa, with 2300 case records, 24 photographs and 50 references to the literature
"A somewhat paradoxical title" might well be the
remark from the theoretical point of view. "t.hy; the
diseases are so contrasted as to admit of no comparison and their combination even is denied by some."Granted; when you have, on the one hand, a truth_
ful intelligent European, with the presence or histor
of a Hunterian Chancre, _ Glands, _ Secondary rashes
or tertiary manifestations, and on the other, a native
of the Tropics with an Extragenital mother Yaw, and
the pathegnomonic or, (to employ an expressive
Scottish word) 'Kenspeckle' Eruption of Secondary
Yaws. "Ca saute aux Yeux ".With these classical features of the two disease
I am not concerned, since they admit of no discussion
when so portrayed, but,let us plunge into Central
Africa among a people recently more primitive than
those of Old Testament narrative, and we can readily
understand if opinion is still divided as to the
identity of the widely differing diseases mentioned
in the Bible, what chance the /African native had in
the past of differentiating Yaws and Syphilis for
himself. Further, _ what chance has the skilled
observer even now of obtaining a satisfactory history
of one or other or perhaps of both diseases.When he comes to examine the lesions he may be
even more at sea. He is at once 'up against' the
black skin; he finds the lesions perhaps obscured by
dirt or native medicines, and, if not superimposed
on tissues already attacked by other diseases, e.g.
Filarasis, Leprosy or Tubercle, he may find them so
profoundly altered by deficiency disease, tropical
anaemias, secondary infection, or all three that he
cannot even say with any certainty that they are
Spirochaetal in origin, let alone, differentiate the
particular species concerned. Little wonder then,
that many have considered them one and the same.Such an observer is of necessity denied the
crucial tests of microscopical, histological and
serological diagnosis, and he must therefore fall
back on other and more unorthodox means; he must
familiarise himself with the combinations and one
might even say the permutations of his two diseases
with each other and with the other local conditions
already mentioned, and he must know something of the
history of the diseases he is treating and the people
he is working among.It is then along these lines and with these
reservations that I wish to discuss the subject.
Fortunate it is that the mass diagnosis of these
diseases, so liable to be confused and so profoundly
altered by concomitant conditions, is merely of
statistical interest, and that the mass treatment of
both is only a matter of intensity
Higgs Boson Search Sensitivity in the Dilepton Decay Mode at and 10 TeV
Prospects for discovery of the standard model Higgs boson are examined at
center of mass energies of and TeV at the CERN Large Hadron Collider.
We perform a simulation of the signal and principal backgrounds for Higgs boson
production and decay in the dilepton mode, finding good agreement
with the ATLAS and CMS collaboration estimates of signal significance at 14 TeV
for Higgs boson masses near ~GeV. At the lower energy of ~TeV,
using the same analysis cuts as these collaborations, we compute expected
signal sensitivities of about standard deviations ('s) at ~GeV in the ATLAS case, and about 3.6~ in the CMS case for
~fb of integrated luminosity. Integrated luminosities of
8~ and 3~ are needed in the ATLAS case at and
~TeV, respectively, for level discovery. In the CMS case, the
numbers are 2~ and 1~ at and ~TeV. Our
different stated expectations for the two experiments arise from the more
restrictive analysis cuts in the CMS case. Recast as exclusion limits, our
results show that with of integrated luminosity at 7~TeV, the
LHC may be able to exclude values in the range 160 to 180~GeV provided no
signal is seen.Comment: 29 pages, 8 figures. New results on estimated discovery reach for
both CMS and ATLAS, as well as exclusion limits, along with comparisons with
Tevatron possibilities. References added
Measuring overlaps in mesoscopic spin glasses via conductance fluctuations
We consider the electonic transport in a mesoscopic metallic spin glasses. We
show that the distribution of overlaps between spin configurations can be
inferred from the reduction of the conductance fluctuations by the magnetic
impurities. Using this property, we propose new experimental protocols to probe
spin glasses directly through their overlaps
Design of automatic milking system for use in pasture-based systems
End of Project ReportA commercial vision system was successful in identifying target artificial teats in various and demanding scenarios, but the system is very prone to making false identifications.
A robotic manipulator capable of the simultaneous handling of four milking cups has been designed.
The end-effector profile is sufficiently compact to allow access between the rear legs of the cow while enabling full access to all four teats for application of milking cups.
The positioning response of the end-effecter is satisfactory for accommodating small changes in teat position during milking cup application
Superconducting instability in 3 band metallic nanotubes
Motivated by recent experiments on small radius nanotubes, we study the
superconducting instabilities of cylindrical (5,0) nanotubes. According to band
structure calculations, thesenanotubes possess three bands at the Fermi energy.
Using a fermionic renormalization group approach and a careful bosonization
treatment,we consider the effect of different attractive interactions, mediated
by phonons, within the Luttinger Liquid framework. We particularly focus on a
superconducting instability specific to the three bands model we consider for
the description of these
(5,0) cylindrical nanotubes.Comment: RevTeX 4, 17 pages, 10 EPS figure
Modeling Adaptation with Klaim
In recent years, it has been argued that systems and applications, in order to deal with their increasing complexity, should be able to adapt their behavior according to new requirements or environment conditions. In this paper, we present an investigation aiming at studying how coordination languages and formal methods can contribute to a better understanding, implementation and use of the mechanisms and techniques for adaptation currently proposed in the literature. Our study relies on the formal coordination language Klaim as a common framework for modeling some well-known adaptation techniques: the IBM MAPE-K loop, the Accord component-based framework for architectural adaptation, and the aspect- and context-oriented programming paradigms. We illustrate our approach through a simple example concerning a data repository equipped with an automated cache mechanism
A fluid-walled microfluidic platform for human neuron microcircuits and directed axotomy â€
In our brains, different neurons make appropriate connections; however, there remain few in vitro models of such circuits. We use an open microfluidic approach to build and study neuronal circuits in vitro in ways that fit easily into existing bio-medical workflows. Dumbbell-shaped circuits are built in minutes in standard Petri dishes; the aqueous phase is confined by fluid walls – interfaces between cell-growth medium and an immiscible fluorocarbon, FC40. Conditions are established that ensure post-mitotic neurons derived from human induced pluripotent stem cells (iPSCs) plated in one chamber of a dumbbell remain where deposited. After seeding cortical neurons on one side, axons grow through the connecting conduit to ramify amongst striatal neurons on the other – an arrangement mimicking unidirectional cortico-striatal connectivity. We also develop a moderate-throughput non-contact axotomy assay. Cortical axons in conduits are severed by a media jet; then, brain-derived neurotrophic factor and striatal neurons in distal chambers promote axon regeneration. As additional conduits and chambers are easily added, this opens up the possibility of mimicking complex neuronal networks, and screening drugs for their effects on connectivity
Non-Abelian Excitations of the Quark-Gluon Plasma
We present new, non-abelian, solutions to the equations of motion which
describe the collective excitations of a quark-gluon plasma at high
temperature. These solutions correspond to spatially uniform color
oscillations.Comment: 8 pages LaTex, 1 figure (not included; available upon request),
Saclay preprint T94/0
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