Final Cultural Resources Report For The Salt Creek Midstream, LLC Proposed Waha II Pipeline Project On State Of Texas Lands In Reeves County, Texas

Enercon Services, Inc. (ENERCON), in support of Salt Creek Midstream, LLC, conducted an intensive archeological survey for the proposed Waha II Pipeline Project. The proposed pipeline is approximately 27.33 miles in length, located near Pecos, Texas in Reeves County. This report encompasses only the two State of Texas Lands, administered by the Texas General Land Office (TGLO), segments of the proposed Waha II Pipeline Project which is approximately 0.69-miles (3,666 feet) in length in Reeves County. The State of Texas Lands portion of the project area is mapped on the United States Geological Survey (USGS) Toyah Lake, Tex. (1963), and Old X Ranch, Tex. (1963, Photorevised 1981), 7.5 Minute Quadrangles. The construction corridor consists of a 50-foot-wide permanent pipeline right-of-way (ROW) and a 50-footwide temporary workspace corridor. The cultural resources survey corridor was 100 feet wide for the entire 0.69-mile length of the pipeline segment through the State of Texas Lands. The total area inspected during the cultural resources survey of the State of Texas Lands was 8.43 acres (3.41 hectares). The survey of the State of Texas property was completed under Texas Antiquities Permit No. 9017. The cultural resources field investigation on State of Texas Lands occurred on August 2 and 3, 2018 by J. Matthew Oliver and Gary D. Edington and consisted of an intensive pedestrian survey utilizing transects not spaced greater than 15 meters apart with shovel tests. The field investigation was conducted in accordance with the Texas Historical Commission (THC) Archeological Survey Standards for Texas. The entire project was supervised by Gary D. Edington, an ENERCON archeologist who meets the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. The cultural resources survey resulted in the observation of two isolated finds (IF). IF#8 is a single lithic flake of brown chert observed on the surface in the east tract of State of Texas Lands. IF#9 is a small bulldozer push-pile of old wooden fence posts and barbed wire observed adjacent to the east fence line of the east tract of Texas State lands. IF#8 and IF#9 lack information potential and are not eligible for the National Register of Historic Places (NRHP) or State Antiquities Landmarks (SAL). The cultural resources survey did not result in finding any additional historic or prehistoric artifacts, features, cultural lenses, or sites over 50 years of age on State of Texas Lands. No archeological sites were encountered, and no artifacts were collected. Therefore, it is recommended that the project will have no effect on any cultural resources that may qualify for inclusion to the NRHP on State of Texas Lands. No further cultural resources investigations are recommended prior to construction of the proposed Waha II Pipeline project on State of Texas Lands. If cultural material, including sites, features, or artifacts that are 50 years old or older are encountered within the ROW during construction of this project, work in the area must cease and the regional THC Archeologist must be immediately be notified

Cultural Resources Report For The Salt Creek Midstream, LLC Proposed Halcon Pipeline On Texas General Land Office Lands In Reeves County, Texas

Enercon Services, Inc. (ENERCON), in support of Salt Creek Midstream, LLC, conducted an intensive cultural resources survey for the proposed Halcon Pipeline. The proposed pipeline is approximately 43.3 miles (69.7 km) in length and located near Pecos, Texas in Ward and Reeves counties. This report encompasses only the portion of the proposed Halcon Pipeline located on two tracts of Permanent School Fund land in Reeves County, Texas. The Permanent School Fund is administered by the Texas General Land Office (TGLO), a political subdivision of the State of Texas. The portion of the Halcon Pipeline on TGLO lands is approximately 1.8 miles (2.8 km) in length and depicted on the United States Geological Survey (USGS) Quito Draw, Tex. (1963, Photorevised 1981), Old X Ranch, Tex. (1963, Photorevised 1981), Toyah Lake, Tex. (1963) 7.5 Minute Quadrangle maps. The construction corridor consists of a 50 feet (15 m) wide permanent pipeline right-of-way (ROW) and an additional 50 feet (15 m) wide temporary workspace corridor. The cultural resources survey area of potential effect (APE) consists of the 1.8 mile (2.8 km) by 100 feet (30 m) corridor, totaling 21.3 acres (8.6 hectares). The cultural resources investigation is intended to assist in adhering to the 1969 Antiquities Code of Texas and the cultural resources survey on TGLO lands was completed under Texas Antiquities Permit No. 8275. The entire project was supervised by Michael M. Margolis, an ENERCON archeologist who meets the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. Prior to the survey, a search of the Texas Archeological Sites Atlas (the Atlas) was conducted by Michael M. Margolis to locate previously recorded archeological sites, archeological surveys, National Register of Historic Places (NRHP) properties, and State Antiquities Landmarks (SALs). Based on the Atlas, one site, 41RV60, has been previously recorded within 1-mile of the APE on TGLO lands. Site 41RV60 is an Early Archaic lithic scatter recorded by URS Corporation in March 2014 and was determined ineligible for listing on the NRHP by the State Historic Preservation Officer (SHPO) on April 8, 2014. Site 41RV60 is located approximately 4,500 feet (1,372 m) from the APE and will not be impacted by construction of the proposed Halcon Pipeline. Two archeological surveys or studies are mapped within 1-mile of the APE on TGLO lands. The cultural resources survey of the Halcon Pipeline APE on TGLO lands was conducted December 1-2, 2017 by Julie Wasinger and Gary D. Edington, ENERCON archeologists who meet the U.S. Secretary of the Interior’s Professional Qualification Standards for archeology as set forth in 36 CFR 61. Salt Creek Midstream, LLC procedures dictate that all standing structures be avoided during construction. Fieldwork was conducted in accordance with the Texas Historical Commission (THC) Archeological Survey Standards for Texas. The cultural resources survey of the Halcon Pipeline APE did not result in finding any historic or prehistoric artifacts, features, cultural lenses, or sites and no artifacts were collected on TGLO lands. Therefore, it is recommended that construction of the proposed Halcon Pipeline on TGLO lands will have no effect on any historic property that may qualify for inclusion on the NRHP or SAL listings. No further cultural resources investigations are recommended prior to construction of the proposed Halcon Pipeline on TGLO lands. If cultural material, including sites, features, or artifacts that are 50 years old or older are encountered within the APE during construction of the Halcon Pipeline on TGLO lands, work in the area must cease and the regional THC Archeologist (512-463-6096) must be notified immediately

Integration of systems biology with organs-on-chips to humanize therapeutic development

"Mice are not little people" - a refrain becoming louder as the gaps between animal models and human disease become more apparent. At the same time, three emerging approaches are headed toward integration: powerful systems biology analysis of cell-cell and intracellular signaling networks in patient-derived samples; 3D tissue engineered models of human organ systems, often made from stem cells; and micro-fluidic and meso-fluidic devices that enable living systems to be sustained, perturbed and analyzed for weeks in culture. Integration of these rapidly moving fields has the potential to revolutionize development of therapeutics for complex, chronic diseases, including those that have weak genetic bases and substantial contributions from gene-environment interactions. Technical challenges in modeling complex diseases with "organs on chips" approaches include the need for relatively large tissue masses and organ-organ cross talk to capture systemic effects, such that current microfluidic formats often fail to capture the required scale and complexity for interconnected systems. These constraints drive development of new strategies for designing in vitro models, including perfusing organ models, as well as "mesofluidic" pumping and circulation in platforms connecting several organ systems, to achieve the appropriate physiological relevance. Keywords: organs-on-chips; 3D liver culture; perfusion; drug development; inflammation; organ crosstalk; tissue chip; intestineUnited States. Defense Advanced Research Projects Agency (Award W911NF-12-2- 0039))National Institutes of Health (U.S.) (Grant UH3TR000496

Assessment of possible impact of a health promotion program in Korea from health risk trends in a longitudinally observed cohort

BACKGROUND: Longitudinally observed cohort data can be utilized to assess the potential for health promotion and healthcare planning by comparing the estimated risk factor trends of non-intervened with that of intervened. The paper seeks (1) to estimate a natural transition (patterns of movement between states) of health risk state from a Korean cohort data using a Markov model, (2) to derive an effective and necessary health promotion strategy for the population, and (3) to project a possible impact of an intervention program on health status. METHODS: The observed transition of health risk states in a Korean employee cohort was utilized to estimate the natural flow of aggregated health risk states from eight health risk measures using Markov chain models. In addition, a reinforced transition was simulated, given that a health promotion program was implemented for the cohort, to project a possible impact on improvement of health status. An intervened risk transition was obtained based on age, gender, and baseline risk state, adjusted to match with the Korean cohort, from a simulated random sample of a US employee population, where a health intervention was in place. RESULTS: The estimated natural flow (non-intervened), following Markov chain order 2, showed a decrease in low risk state by 3.1 percentage points in the Korean population while the simulated reinforced transition (intervened) projected an increase in low risk state by 7.5 percentage points. Estimated transitions of risk states demonstrated the necessity of not only the risk reduction but also low risk maintenance. CONCLUSIONS: The frame work of Markov chain efficiently estimated the trend, and captured the tendency in the natural flow. Given only a minimally intense health promotion program, potential risk reduction and low risk maintenance was projected

The influence of transition metal solutes on dislocation core structure and values of Peierls stress and barrier in tungsten

Several transition metals were examined to evaluate their potential for improving the ductility of tungsten. The dislocation core structure and Peierls stress and barrier of $1/2$ screw dislocations in binary tungsten-transition metal alloys (W$_{1-x}$TM$_{x}$) were investigated using first principles electronic structure calculations. The periodic quadrupole approach was applied to model the structure of $1/2$ dislocation. Alloying with transition metals was modeled using the virtual crystal approximation and the applicability of this approach was assessed by calculating the equilibrium lattice parameter and elastic constants of the tungsten alloys. Reasonable agreement was obtained with experimental data and with results obtained from the conventional supercell approach. Increasing the concentration of a transition metal from the VIIIA group, i.e. the elements in columns headed by Fe, Co and Ni, leads to reduction of the $C^\prime$ elastic constant and increase of elastic anisotropy A=$C_{44}/C^\prime$. Alloying W with a group VIIIA transition metal changes the structure of the dislocation core from symmetric to asymmetric, similar to results obtained for W$_{1-x}$Re$_{x}$ alloys in the earlier work of Romaner {\it et al} (Phys. Rev. Lett. 104, 195503 (2010))\comments{\cite{WRECORE}}. In addition to a change in the core symmetry, the values of the Peierls stress and barrier are reduced. The latter effect could lead to increased ductility in a tungsten-based alloy\comments{\cite{WRECORE}}. Our results demonstrate that alloying with any of the transition metals from the VIIIA group should have similar effect as alloying with Re.Comment: 12 pages, 8 figures, 3 table

Skin Cancers Among Albinos at a University Teaching Hospital in Northwestern Tanzania: A Retrospective Review of 64 Cases.

Skin cancers are a major risk associated with albinism and are thought to be a major cause of death in African albinos. The challenges associated with the care of these patients are numerous and need to be addressed. The aim of this study was to outline the pattern and treatment outcome of skin cancers among albinos treated at our centre and to highlight challenges associated with the care of these patients and proffer solutions for improved outcome. This was a retrospective study of all albinos with a histopathological diagnosis of skin cancer seen at Bugando Medical Centre from March 2001 to February 2010. Data collected were analyzed using descriptive statistics. A total of 64 patients were studied. The male to female ratio was 1.5:1. The median age of patients was 30 years. The median duration of illness at presentation was 24 months. The commonest reason for late presentation was financial problem. Head and the neck was the most frequent site afflicted in 46(71.8%) patients. Squamous cell carcinoma was the most common histopathological type in 75% of cases. Surgical operation was the commonest modality of treatment in 60 (93.8%) patients. Radiotherapy was given in 24(37.5%) patients. Twenty-seven (42.2%) of the patients did not complete their treatment due to lack of funds. Local recurrence following surgical treatment was recorded in 6 (30.0%) patients. Only thirty-seven (61.7%) patients were available for follow-up at 6-12 months and the remaining patients were lost to follow-up. Skin cancers are the most common cancers among albinos in our environment. Albinism and exposure to ultraviolet light appears to be the most important risk factor in the development of these cancers. Late presentation and failure to complete treatment due to financial difficulties and lack of radiotherapy services at our centre are major challenges in the care of these patients. Early institution of preventive measures, early presentation and treatment, and follow-up should be encouraged in this population for better outcome

Photochemistry Of Monochloro Complexes Of Copper(ii) In Methanol Probed By Ultrafast Transient Absorption Spectroscopy

Ultrafast transient absorption spectra in the deep to near UV range (212-384 nm) were measured for the [Cu-II(MeOH)(5)Cl](+) complexes in methanol following 255-nm excitation of the complex into the ligand-to-metal charge-transfer excited state. The electronically excited complex undergoes sub-200 fs radiationless decay, predominantly via back electron transfer, to the hot electronic ground state followed by fast vibrational relaxation on a 0.4-4 Ps time scale. A minor photochemical channel is Cu-Cl bond dissociation, leading to the reduction of copper(H) to copper(I) and the formation of MeOH center dot Cl charge-transfer complexes. The depletion of ground-state [Cu-II(MeOH)(5)Cl](+) perturbs the equilibrium between several forms of copper(II) complexes present in solution. Complete re-equilibration between [Cu-II(MeOH)(5)Cl](+) and [Cu-II(MeOH)(4)Cl-2] is established on a 10-500 ps time scale, slower than methanol diffusion, suggesting that the involved ligand exchange mechanism is dissociative

Body composition in older acute stroke patients after treatment with individualized, nutritional supplementation while in hospital

<p>Abstract</p> <p>Background</p> <p>Individualized, nutritional support reduced undernutrition among older stroke patients and improved quality of life in our recent randomized, controlled trial. Weight control thus seems to be important after stroke, and methods for monitoring nutritional status need to be simple and non-invasive. Here we aimed to assess if the nutritional intervention altered body composition in men and women in this study cohort, and also to examine the correlation between the methods for assessing body-, fat- and fat-free mass.</p> <p>Methods</p> <p>Acute stroke patients > 65 years at nutritional risk were randomized to either individualized, nutritional treatment with energy- and protein rich supplementation (intervention, n = 58) or routine, nutritional care (control, n = 66) while in hospital. Body composition was assessed with anthropometry and bioelectrical impedance. The follow-up period was three months.</p> <p>Results</p> <p>During the first week while in hospital, weight loss was smaller in the intervention group compared with the controls (P = 0.013). After three months weight- and fat loss were significant in both men and women. Whereas no significant differences were found in changes in body composition between the male study groups, in the women both weight loss (P = 0.022) and fat loss (P = 0.005) was smaller in the intervention group compared with the controls. A high correlation (r = 0.87) between mid upper arm circumference (MUAC) and body mass index (BMI) was found.</p> <p>Conclusions</p> <p>Individualized nutritional support to older stroke patients in hospital was beneficial for maintaining an adequate body mass and body composition the first week and seemed to have a preventive effect on fat loss among women, but not among men after three months. Measurement of MUAC may be used in the assessment of nutritional status when BMI cannot be obtained.</p> <p>Trial registration</p> <p>This trial is registered with ClinicalTrials.gov, number NCT00163007.</p

Characteristics of undernourished older medical patients and the identification of predictors for undernutrition status

<p>Abstract</p> <p>Background</p> <p>Undernutrition among older people is a continuing source of concern, particularly among acutely hospitalized patients. The purpose of the current study is to compare malnourished elderly patients with those at nutritional risk and identify factors contributing to the variability between the groups.</p> <p>Methods</p> <p>The study was carried out at the Soroka University Medical Center in the south of Israel. From September 2003 through December 2004, all patients 65 years-of-age or older admitted to any of the internal medicine departments, were screened within 72 hours of admission to determine nutritional status using the short version of the Mini Nutritional Assessment (MNA-SF). Patients at nutritional risk were entered the study and were divided into malnourished or 'at risk' based on the full version of the MNA. Data regarding medical, nutritional, functional, and emotional status were obtained by trained interviewers.</p> <p>Results</p> <p>Two hundred fifty-nine elderly patients, 43.6% men, participated in the study; 18.5% were identified as malnourished and 81.5% were at risk for malnutrition according to the MNA. The malnourished group was less educated, had a higher depression score and lower cognitive and physical functioning. Higher prevalence of chewing problems, nausea, and vomiting was detected among malnourished patients. There was no difference between the groups in health status indicators except for subjective health evaluation which was poorer among the malnourished group. Lower dietary score indicating lower intake of vegetables fruits and fluid, poor appetite and difficulties in eating distinguished between malnourished and at-risk populations with the highest sensitivity and specificity as compare with the anthropometric, global, and self-assessment of nutritional status parts of the MNA. In a multivariate analysis, lower cognitive function, education <12 years and chewing problems were all risk factors for malnutrition.</p> <p>Conclusion</p> <p>Our study indicates that low food consumption as well as poor appetite and chewing problems are associated with the development of malnutrition. Given the critical importance of nutritional status in the hospitalized elderly, further intervention trials are required to determine the best intervention strategies to overcome these problems.</p