Flowchart of the followed methodology.

<p>A. Health worker taking a photo of a radiograph. B. Opening JPEG files with GIMP software. C. Selection of the area. D. Pixel quantification. E. Selected “affected area.”</p

Intraclass correlation agreement between rater A and B.

<p>Intraclass correlation agreement between rater A and B.</p

Chest X-ray showing patchy infiltrates in both lungs.

<p>Chest X-ray showing patchy infiltrates in both lungs.</p

Flow diagram for study selection.

<p>Flow diagram for study selection.</p

Forest plots of prevalence of Chagas disease by country of origin of Latin American migrants.

<p>Forest plots of prevalence of Chagas disease by country of origin of Latin American migrants.</p

Signs and symptoms of esophagopathy and association with esophagogram findings.

<p><b>Abbreviations: LES:</b> lower esophageal sphincter; <b>L:</b> in relation to liquids; <b>S:</b> in relation to solids.</p>1<p>More than one symptom in some patients.</p

Colonopathy: Clinical findings and barium enema results.

<p>Colonopathy: Clinical findings and barium enema results.</p

Main characteristics of the studies included in the meta-analysis.

<p>Main characteristics of the studies included in the meta-analysis.</p

Forest plots of prevalence of Chagas disease by country of origin of Latin American migrants.

<p>Forest plots of prevalence of Chagas disease by country of origin of Latin American migrants.</p

Baseline characteristics of patients, including past gastrointestinal history.

1<p>Alcohol intake was reported as occasional in all cases.</p>2<p>Presence of symptoms considered as originating in the gastroduodenal region, in the absence of any organic, systemic, or metabolic disease that is likely to explain the symptoms (Roma III criteria).</p>3<p>One patient presented in her past history pyloric stenosis surgery, showing normal esophagogram and barium enema.</p>4<p>Five patients presented partial colectomy previously of being admitted in the international health centre. After the surgery, one of them presented megasigma, and another one dolichomegacolon. The other three presented dolichocolon. All of them did not showed alterations in esophagogram.</p