35 research outputs found

    Ferulic acid and derivatives: molecules with potential application in the pharmaceutical field

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    Les antioxydants dans la tourmente

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    George Ryga and Slawomir Mrozhek: General and Different

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    Статтю присвячено вивченню принципів побудови п’єс у добу постмодернізму. Увагу зосереджено на творчості канадського митця Джорджа Риги та польського драматурга Славоміра Мрожека. Розглянуто особливості художньої інтерпретації тексту та образів у п’єсах «Лист до мого сина» і «Танго»./ General and Different. The article is devoted to the study of principles of construction of plays in the time of postmodernism. The attention is paid to the creations of the Canadian writer George Ryga and Polish playwright Slawomir Mrozhek. The features of artistic interpretation of text and appearances are established in plays “A Letter to My Son” and “Tango”. It’s investigated the general problems of George Ryga and Slavomir Mrozhek plays.Комінярський І. Джордж Рига та Славомір Мрожек: спільне і відмінне / Ілля Камінярський // Науковий вісник Східноєвропейського національного університету. Сер. «Філологічні науки. Літературознавство». – 2014. – № 9 (286). – С. 70-73

    In vivo visualization and quantification of mitochondrial morphology in C. elegans

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    Caenorhabditis elegans is a highly malleable model system, intensively used for functional, genetic, cytometric, and integrative studies. Due to its simplicity and large muscle cell number, C. elegans has frequently been used to study mitochondrial deficiencies caused by disease or drug toxicity. Here, we describe a robust and efficient method to visualize and quantify mitochondrial morphology in vivo. This method has many practical and technical advantages above traditional (manual) methods and provides a comprehensive analysis of mitochondrial morphology

    Supplementary Material for: Microbiota Quality and Mitochondrial Activity Link with Occurrence of Muscle Cramps in Hemodialysis Patients using Citrate Dialysate: A Pilot Study

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    <b><i>Background/Aims:</i></b> Hemodialysis-associated muscle cramp (HAMC) is a common complication under citrate dialysate (CD) occurring in 30% of cases. Our objectives were to assess the gut microbiota quality, mitochondrial activity, and to investigate their possible relationship with HAMC. <b><i>Methods:</i></b> Ten end-stage renal disease patients (78.9 ± 2.1 years) treated by hemodialysis (HD) with CD were enrolled and then classified according to the frequency of HAMCs: “frequent HAMCs group” (<i>n</i> = 5) and “absence of HAMCs group” (<i>n</i> = 5). Gut microbiota quality, mitochondrial activity, and some markers of oxidative stress (OS) were investigated. <b><i>Results:</i></b> In patients with cramps, gut microbiota diversity seemed lower and some genera including Helicobacter, Lachnospira, Roseburia, and Haemophilus seemed over-expressed, a significant increase of citratemia and significant lowering mitochondrial function were observed. No difference was observed on the OS markers. <b><i>Conclusion:</i></b> This first clinical study revealed a possible dysbiosis of microbiota and a mitochondrial dysfunction into HD patients with cramps under CD compared to patients without cramp
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