62 research outputs found
Integrative Genomics Identifies Gene Signature Associated with Melanoma Ulceration
Abstract Background: Despite the extensive research approaches applied to characterise malignant melanoma, no specific molecular markers are available that are clearly related to the progression of this disease. In this study, our aims were to define a gene expression signature associated with the clinical outcome of melanoma patients and to provide an integrative interpretation of the gene expression -, copy number alterations -, and promoter methylation patterns that contribute to clinically relevant molecular functional alterations
Los Montes Submarinos de la Plataforma Marginal de Motril, Mar de Alborán: Interacción con las Masas de Agua Profunda
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