Assessment of 8-hydroxydeoxyguanosine levels in patients with preeclampsia: A prospective study

WOS: 000396801700013PubMed ID: 29746027Purpose of investigation: To determine the levels of 8-hydroxydeoxyguanosine (8-OHdG) in preeclampsia (PE) using (enzyme linked immunosorbent assay (ELISA) method. Materials and Methods: Twenty-two pregnant women with severe PE, 18 pregnant women with mild PE, and 40 healthy pregnant women, all between 25 and 41 weeks of gestation, were enrolled in this prospective controlled study. 8-OHdG levels in maternal serum were measured using ELISA method. Results: The authors observed no statistically significant difference in 8-OHdG levels between the mild-severe PE and control groups (p = 0.208). Conclusion: The present results do not support the concept that 8-OHdG has a role in the etiopathogenesis of PE.Gaziantep University [TF. 13. 25]This study was granted by the project research unit of Gaziantep University (project number TF. 13. 25)

Attachment, infidelity, and loneliness in college students involved in a romantic relationship: the role of relationship satisfaction, morbidity and prayer for partner

This study examined the mediating effects of relationship satisfaction, prayer for a partner, and morbidity in the relationship between attachment and loneliness, infidelity and loneliness, and psychological morbidity and loneliness, in college students involved in a romantic relationship. Participants were students in an introductory course on family development. This study examined only students (n = 345) who were involved in a romantic relationship. The average age of participants was 19.46 (SD = 1.92) and 25 % were males. Short-form UCLA Loneliness Scale (ULS-8), (Hays and DiMatteo in J Pers Assess 51:69–81, doi:10.1207/s15327752jpa5101_6, 1987); Relationship Satisfaction Scale (Funk and Rogge in J Fam Psychol 21:572–583, doi:10.1037/0893-3200.21.4.572, 2007); Rotterdam Symptom Checklist (De Haes et al. in Measuring the quality of life of cancer patients with the Rotterdam Symptom Checklist (RSCL): a manual, Northern Centre for Healthcare Research, Groningen, 1996); Prayer for Partner Scale, (Fincham et al. in J Pers Soc Psychol 99:649–659, doi:10.1037/a0019628, 2010); Infidelity Scale, (Drigotas et al. in J Pers Soc Psychol 77:509–524, doi:10.1037/0022-3514.77.3.509, 1999); and the Experiences in Close Relationship Scale-short form (Wei et al. in J Couns Psychol 52(4):602–614, doi:10.1037/0022-0167.52.4.602, 2005). Results showed that relationship satisfaction mediated the relationship between avoidance attachment and loneliness and between infidelity and loneliness. Physical morbidity mediated the relationship between anxious attachment and psychological morbidity. Psychological morbidity mediated the relationship between anxious attachment and physical morbidity. The present results expand the literature on attachment by presenting evidence that anxious and avoidant partners experience loneliness differently. Implications for couple’s therapy are addressed. Future research should replicate these results with older samples and married couples.Acknowledgments This research was supported by Grant Number 90FE0022 from the United States Department of Health and Human Services awarded to the last author

Forgiveness Education for Fourth Grade Students in Turkey

WOS: 000388717500013Research has indicated that living in an environment involving poverty and violence can have negative effects on young children. Forgiveness may be an important predictor of well-being among these children. Forgiveness education programs aim to heal these by increasing forgiveness, hope, and by being prosocial while decreasing anger and depression, which appear after deep hurt. The main aim of the study was to assess and evaluate the effectiveness of a forgiveness education program in classroom settings with fourth-grade Turkish students living in an impoverished environment. Two studies were conducted to evaluate the forgiveness education program, based on Enright's process model of forgiveness. In the first study, students from impoverished backgrounds were found to exhibit significantly greater anger and depression than students representing an average socioeconomic status. In the second study, with 122 fourth-grade students (N = 74 experimental, 48 control) in five primary schools, the forgiveness education program was implemented by school teachers with support from psychologists. Analysis reveals a significant increase in forgiveness and hope and a decrease in anger in the first posttest for the experimental group compared with the control group, although follow-up results indicate no significant differences between the two groups. Significant findings and the forgiveness education program are discussed.Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110K429]This research was supported by grant number 110K429 from the Scientific and Technological Research Council of Turkey, awarded to the first author

Ambivalent Sexism as a Mediator for Sex Role Orientation and Gender Stereotypes in Romantic Relationships: A Study in Turkey

The present study examined the mediating effects of ambivalent sexism (hostile and benevolent) in the relationship between sex role orientation (masculinity and femininity) and gender stereotypes (dominance and assertiveness) in college students. The variables were measured using the Bem Sex Role Inventory (BSRI), the Ambivalent Sexism Inventory (ASI), and the Attitudes toward Gender Stereotypes in Romantic Relationships Scale (AGSRRS). These inventories were administered to 250 undergraduate students at Istanbul University in Istanbul and Suleyman Demirel University in Isparta, Turkey. Results indicate that benevolent sexism mediates the relationship between hostile sexism and male dominance. Benevolent sexism also mediates femininity and male dominance, as well as femininity and male assertiveness. Hostile sexism was mediated only between the masculine personality trait and benevolent sexism. The present findings expand the literature on sex role orientation by revealing evidence that masculine and feminine individuals experience ambivalent sexism distinctively. The results are discussed in terms of the assumptions of sex role orientation, ambivalent sexism, and gender stereotypes

Communication, forgiveness and morbidity in young adults involved in a romantic relationship

This study examined the direct and indirect effects of communication patterns and forgiveness on physical and psychological morbidity, among young adults involved in a romantic relationship. Participants were 298 students, currently involved in a heterosexual romantic relationship, from a large university in the United States, who completed the Tendency to Forgive Scale, the Communication Patterns Questionnaire, and the Rotterdam Symptom Checklist. Physical morbidity was directly predicted by mutuality communication. Destructive communication had an indirect effect on physical and psychological morbidity, via forgiveness. However, the indirect connection between destructive communication and psychological morbidity was only significant for female partners. Teaching constructive communication skills may be a key factor for interventions addressed to young adults in romantic relationships, in order to promote forgiveness, due to its potential positive influence in physical and psychological well-being.info:eu-repo/semantics/publishedVersio

Assessment of total sialic acid levels in patients with hyperemesis gravidarum: a preliminary study

To determine the levels of serum total sialic acid (TSA) in patients with hyperemesis gravidarum (HG) and their gestational age-matched controls. Thirty pregnant women with HG, and 30 healthy pregnant women at up to 14 weeks of gestation were enrolled in this preliminary study. Total sialic acid levels in maternal serum were measured using the quantitative sandwich ELISA method. We observed statistically significant difference in TSA levels between HG and the control groups (p = .003). The identification of the role of SA in the prediction, diagnosis and follow-up of HG warrants more comprehensive studies in the future.Impact Statement What is already known on this subject? The derivatives of neuraminic acid are collectively referred to as sialic acid (SA). Changes in SA levels are known to trigger various conditions and disorders, including inflammatory, cardiovascular, neurological and endocrine diseases. Although a sensitive test capable of identifying hyperemesis gravidarum (HG) would be useful for diagnosis purposes, such a test is currently not available. Studies focussing on identifying new potential indicators and biomarkers for HG – as well as identifying their relevance in establishing diagnosis and assessing disease severity – would not only assist in elucidating the underlying causes of this condition but would also contribute to the development of new diagnostic tests for HG. What the results of this study add? Total sialic acid levels are significantly higher in sera of the patients with HG. The present study is the first in the literature to assess total sialic acid levels in patients with HG and healthy pregnant women before 14 weeks of gestation. What the implications are of these findings for clinical practice and/or further research? Total sialic acid levels could give an idea to clinicians in the etiopathogenesis of HG. The identification of the role of sialic acid in the prediction, diagnosis and follow-up of HG warrants more comprehensive studies in the future