ИНТЕНСИВНАЯ ТЕХНОЛОГИЯ ВЫРАЩИВАНИЯ КЛУБНИКИ В ЗАКРЫТОМ ГРУНТЕ

The intensive technology of growing strawberries under cover, the production of maximum yield in the greenhouses, the structure of strawberry beds, the preparation, composting and sterilization of the substrate, raising the seedlings of strawberry, comparative economic evaluation they are KEYWORDS reviewed in the article.The intensive technology of growing strawberries under cover, the production of maximum yield in the greenhouses, the structure of strawberry beds, the preparation, composting and sterilization of the substrate, raising the seedlings of strawberry, comparative economic evaluation they are KEYWORDS reviewed in the article

Increasing flexibility at labor market entry and in the early career: a new conceptual framework for the flexCAREER project

"Continuous full-time work is becoming less frequent in modern societies. Instead, flexible forms of employment such as part-time work, fixed-term contracts, and self-employment as well as phases of unemployment are gaining importance. These trends are supposed to be more pronounced at labor market entry, leading to a prolonged entry process and increasing difficulties in becoming established on the labor market. However, there are vast differences between countries with regard to forms of labor market flexibility and the degrees of uncertainty young people have to face. This working paper provides a theoretical framework for the empirical studies within the flexCAREER research program. The aim of flexCAREER is to study the consequences of employment flexibility strategies on labor market entries and early careers as well as their impact on structures of social inequality in a cross-country perspective. We explain the reasons behind the rise in employment flexibility and develop hypotheses with special regard to nation-based institutional differences. In particular, we describe which role institutional settings such as the educational system, production regimes, employment protection legislations, and labor market policies play in determining the consequences of employment flexibility strategies. We focus on the institutional contexts of Great Britain, the USA, Germany (East and West), France, the Netherlands, Italy, Spain, Denmark, Sweden, Estonia, and Hungary, which are the countries under study. The hypotheses in this working paper concern the following aspects: 1. the phase of labor market entry in terms of a) the duration of search for the first job and b) the quality of this first job (with regard to the flexibility of the employment contract and the 'adequacy' of the job with respect to the employee's educational qualification). 2. In view of the early career, we outline our expectations in terms of a) the risk of unemployment, b) the chances of reentering the labor force when unemployed (e.g., with regard to the duration of unemployment until finding a new job), c) upward and downward mobility, d) the chances of leaving precarious work at the beginning of the career, and e) the risk of making a transition into a precarious form of employment." (author's abstract

ENVIRONMENTAL POLLUTION WITH HEAVY METALS AND SELECTIVE SENSITIVITY OF SOME SPECIES OF MEDICINAL PLANTS

Heavy metals are especially dangerous in the registry of polluting agents of the environment, as the heavy metals are hazardous to human health and it is particularly dangerous because getting the heavy metals into the living organism is a provocative factor of the dangerous disease such as malignant tumors, diseases of cardiovascular system or nervous system.The problem of the environmental pollution with heavy metals is a priority and urgent problem. Therefore, we aimed to study the peculiarities of the accumulation and dynamics of heavy metals in the polluted and clean environment in different types of medicinal plants grown in Adjara region. The study of annual absorption of heavy metal in the medicinal plants, I think, will have a practical value, because since we often use medicinal plants to help prevent different diseases, it is possible to provoke another disease. Through the plants we used to study.Heavy metals are especially dangerous in the registry of polluting agents of the environment, as the heavy metals are hazardous to human health and it is particularly dangerous because getting the heavy metals into the living organism is a provocative factor of the dangerous disease such as malignant tumors, diseases of cardiovascular system or nervous system.The problem of the environmental pollution with heavy metals is a priority and urgent problem. Therefore, we aimed to study the peculiarities of the accumulation and dynamics of heavy metals in the polluted and clean environment in different types of medicinal plants grown in Adjara region. The study of annual absorption of heavy metal in the medicinal plants, I think, will have a practical value, because since we often use medicinal plants to help prevent different diseases, it is possible to provoke another disease. Through the plants we used to study

CURING OF DIGLYCIDAL ESTERS OF BISPHENOLS WITH AMINE HARDENERS

The effect of hardeners on the properties of cured epoxy polymers is studied. For the purpose of synthesis of polymers with increased thermal properties. Theglycide esters of polycyclic bisphenols synthesized by us were used as a diol component. Since the thermal and heat resistance of polymers, in addition to the chemical structure of bisphenols, also depend on the structure of the hardener used, amine hardeners of different chemical structure are used to improve the thermal parameters of polymers, both heat resistance and heat resistance. The influence of the chemical structure of these hardeners on the properties of epoxy polymers is studied. Cured epoxy polymers are characterized by high heat resistance. High heat resistance results are obtained by 4,4′-diaminodiphenylsulfone, benzidine, 4,4′-diaminodiphenyloxide and other aromatic diamines. Polymers obtained by curing with these hardeners are deformed in the temperature range of 220-245°C. The use of the above hardeners gives high results in terms of heat resistance. In all cases, the polymers obtained on the basis of these hardeners decrease in weight by 10% in the temperature range of 340-400°C.The effect of hardeners on the properties of cured epoxy polymers is studied. For the purpose of synthesis of polymers with increased thermal properties. Theglycide esters of polycyclic bisphenols synthesized by us were used as a diol component. Since the thermal and heat resistance of polymers, in addition to the chemical structure of bisphenols, also depend on the structure of the hardener used, amine hardeners of different chemical structure are used to improve the thermal parameters of polymers, both heat resistance and heat resistance. The influence of the chemical structure of these hardeners on the properties of epoxy polymers is studied. Cured epoxy polymers are characterized by high heat resistance. High heat resistance results are obtained by 4,4′-diaminodiphenylsulfone, benzidine, 4,4′-diaminodiphenyloxide and other aromatic diamines. Polymers obtained by curing with these hardeners are deformed in the temperature range of 220-245°C. The use of the above hardeners gives high results in terms of heat resistance. In all cases, the polymers obtained on the basis of these hardeners decrease in weight by 10% in the temperature range of 340-400°C

Flexibility processes and social inequalities at labor market entry and in the early career: a conceptual paper for the flexCAREER project

"Continuous full-time work is becoming less frequent in modern societies. Instead, flexible forms of employment such as part-time work, fixed-term contracts, and self-employment as well as phases of unemployment are gaining importance. These trends are supposed to be more pronounced at labor market entry, leading to a longer entry process and increasing difficulties in becoming established in the labor market. However, there are vast differences between countries with regard to forms of labor market flexibility and the degree of uncertainty faced by young people. This working paper provides a theoretical framework for the empirical studies within the flexCAREER research program. The aim of flexCAREER is to study the consequences of employment flexibility strategies on labor market entries and early careers as well as their impact on structures of social inequality in a cross-country perspective. We explain the reasons behind the rise in employment flexibility and develop hypotheses with special regard to nation-based institutional differences. In particular, we describe what role institutions such as the education system, employment relations, and welfare regimes play in determining the consequences of employment flexibility strategies. We focus on the institutional contexts of Great Britain, the USA, Germany (East and West), the Netherlands, Italy, Spain, Denmark, Sweden, Estonia, and Hungary; these are the countries under study within the project. The hypotheses in this working paper concern the following aspects: 1. the phase of labor market entry in terms of a) the duration of search for the first job and b) the quality of this first job (with regard to the flexibility of the employment contract and the 'adequacy' of the job with respect to the employee's educational qualification). 2. In view of the early career we outline our expectations in terms of a) the risk of unemployment, b) the chances of re-entering the labor force when unemployed (e.g., with regard to the duration of unemployment until finding a new job), c) upward and downward mobility, d) the chances of leaving precarious work at the beginning of the career, and e) the risk of making a transition into a precarious form of employment." (author's abstract

DNMT1-interacting RNAs block gene specific DNA methylation

Summary DNA methylation was described almost a century ago. However, the rules governing its establishment and maintenance remain elusive. Here, we present data demonstrating that active transcription regulates levels of genomic methylation. We identified a novel RNA arising from the CEBPA gene locus critical in regulating the local DNA methylation profile. This RNA binds to DNMT1 and prevents CEBPA gene locus methylation. Deep sequencing of transcripts associated with DNMT1 combined with genome-scale methylation and expression profiling extended the generality of this finding to numerous gene loci. Collectively, these results delineate the nature of DNMT1-RNA interactions and suggest strategies for gene selective demethylation of therapeutic targets in disease

Spinocerebellar mossy fiber terminal topography in the NR2C/PKC3/ double mutant cerebellum

Abstract The spatiotemporal expression patterns of the NR2C subunit of the NMDA receptor and PKCT isoform during cerebellar development suggests that both proteins are involved in the molecular mechanisms of synaptogenesis. However, the topographic distribution of WGA-HRP labeled spinocerebellar mossy fiber terminals in NR2C/PKCT double mutants (n = 4) appears similar to controls (n = 3). While the results do not rule out a role for NR2C receptor subunits and the PKCy isoform in cerebellar synaptogenesis, they indicate that neither is necessary for the formation or maintenance of normal spinocerebellar mossy fiber afferent maps. Mossy fibers project to the cerebellar cortex in distinctive topographic projection patterns. Although mossy fibers ultimately synapse on granule cell dendrites, the available evidence suggests that the topography of mossy fiber projections is initially organized by Purkinje cells To analyze the role of activity-dependent mechanisms for synapse stabilization in the formation and maintenance of mossy fiber topographic projections, we have analyzed the distribution of spinocerebellar mossy fiber terminals in mutant mice with genetic knockouts of the NR2C subunit of the NMDA receptor [11] and the T subtype of calciumphospholipid-dependent protein kinase (PKCT) We have chosen to focus our analysis on deletions of NR2C and PKCT isoforms because their spatiotemporal expression patterns in the cerebellum suggest that they may be involved in cerebellar synaptogenesi

Vocational Education and Training and Transitions into the Labor Market

Stage 6 of the German National Educational Panel Study (NEPS) 6 is devoted to the transition of young people from school to work. Stage 6 focuses in particular on the transition from school to vocational education and training and then to work (for tertiary education, see Chap. 16). In all Western societies, vocational education and training (VET) systems face a number of challenges, including the need to adapt to increasing skill requirements across the economy and to handle the danger of producing an "underclass" of low-skilled youth. This chapter presents the life-course approach for investigating school-leavers' pathways from school into the labor market within NEPS. Several factors shape young people’s school-to-work transitions: their motivation and competence endowment, their decisions to apply for specific educational programs, the constraints they face regarding the opportunities for VET programs and the gatekeepers’ recruitment behavior, the information and support youths may or may not receive from social networks, and the learning environments they encounter in firms and schools. We outline the basic theories that guide our research concerning these influences and discuss how we take them into account within NEPS Stage 6. Thus, we provide an overview of the study’s research potential in the area of VET. For now, it is mainly the Scientific Use Files of Starting Cohort 4 (SC4) that provide ample opportunities for innovative interdisciplinary analyses - including analyses of students from special education schools. As the starting cohorts age, Starting Cohort 3 (SC3) has now also entered NEPS Stage 6 and its data on VET transitions will soon be available as well

Nvestıgatıon of morphologıcal and bıologıcal aspects of old and young mandarın orchards ın acara regıon of georgıa

Mandalina yetiştiriciliği Acara Özerk Cumhuriyetinin önemli gelir kaynaklarından birdir. Bu çalışmada yaşlı mandalina alanlarının gençleştirilmesinde uygulanabilecek farklı yöntemler karşılaştırılmıştır.Mandarin farming is an important income for the farmers in Acara Region of Georgia. In this study, the methods of converting old infertile mandarin orchards into young fertile orchards were discussed

Acetylation of C/EBP alpha inhibits its granulopoietic function

CCAAT/enhancer-binding protein alpha (C/EBP alpha) is an essential transcription factor for myeloid lineage commitment. Here we demonstrate that acetylation of C/EBP alpha at lysine residues K298 and K302, mediated at least in part by general control non-derepressible 5 (GCN5), impairs C/EBP alpha DNA-binding ability and modulates C/EBP alpha transcriptional activity. Acetylated C/EBP alpha is enriched in human myeloid leukaemia cell lines and acute myeloid leukaemia (AML) samples, and downregulated upon granulocyte-colony stimulating factor (G-CSF)-mediated granulocytic differentiation of 32Dcl3 cells. C/EBP alpha mutants that mimic acetylation failed to induce granulocytic differentiation in C/EBP alpha-dependent assays, in both cell lines and in primary hematopoietic cells. Our data uncover GCN5 as a negative regulator of C/EBP alpha and demonstrate the importance of C/EBP alpha acetylation in myeloid differentiation